Streptokinase Lysis of Intraventricular Thrombus and Pulmonary Emboli with Resolution of Acquired Intracardiac Shunt

Venous aneurysms are uncommon but they can have devastating consequences, including pulmonary embolism, other thromboembolic events and death. We report six cases of venous aneurysm of the extremities, in which the first sign of presence was acute pulmonary embolism. Surgical resection is recommended whenever possible. Our experience suggests that prophylactic surgery is cautiously recommended for low-risk patients with venous aneurysms of the abdomen and strongly recommended for extremity deep and superficial venous aneurysms for their potential risk of developing thromboembolic complications despite adequate anticoagulation. Other venous aneurysms should be excised only if they are symptomatic or enlarging.

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A Comparative Analysis of D-Dimer Assays in Patients with Clinically Suspected Pulmonary Embolism

Thrombosis and Haemostasis ◽

10.1055/s-0038-1649595 ◽

1993 ◽

Vol 70 (03) ◽

pp. 408-413 ◽

Cited By ~ 43

Author(s):

Edwin J R van Beek ◽

Bram van den Ende ◽

René J Berckmans ◽

Yvonne T van der Heide ◽

Dees P M Brandjes ◽

...

Keyword(s):

Pulmonary Embolism ◽

Comparative Analysis ◽

High Probability ◽

Pulmonary Emboli ◽

Plasma Samples ◽

Suspected Pulmonary Embolism ◽

Lung Scan ◽

D Dimer

SummaryTo avoid angiography in patients with clinically suspected pulmonary embolism and non-diagnostic lung scan results, the use of D-dimer has been advocated. We assessed plasma samples of 151 consecutive patients with clinically suspected pulmonary embolism. Lung scan results were: normal (43), high probability (48) and non-diagnostic (60; angiography performed in 43; 12 pulmonary emboli). Reproducibility, cut-off values, specificity, and percentage of patients in whom angiography could be avoided (with sensitivity 100%) were determined for two latex and four ELISA assays.The latex methods (cut-off 500 μg/1) agreed with corresponding ELISA tests in 83% (15% normal latex, abnormal ELISA) and 81% (7% normal latex, abnormal ELISA). ELISA methods showed considerable within- (2–17%) and between-assay Variation (12–26%). Cut-off values were 25 μg/l (Behring), 50 μg/l (Agen), 300 μg/l (Stago) and 550 μg/l (Organon). Specificity was 14–38%; in 4–15% of patients angiography could be avoided.We conclude that latex D-dimer assays appear not useful, whereas ELISA methods may be of limited value in the exclusion of pulmonary embolism.

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Prediction of Susceptibility to Acute Mountain Sickness Using Hypoxia-Induced Intrapulmonary Arteriovenous Shunt and Intracardiac Shunt Fractions

10.21236/ada612590 ◽

2012 ◽

Author(s):

Andrew T. Lovering

Keyword(s):

Acute Mountain Sickness ◽

Arteriovenous Shunt ◽

Intracardiac Shunt ◽

Mountain Sickness

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Do hemodynamics matter in the treatment of patients with submassive pulmonary emboli?

Catheterization and Cardiovascular Interventions ◽

10.1002/ccd.28691 ◽

2020 ◽

Vol 95 (5) ◽

Author(s):

Morton J. Kern ◽

Arnold H. Seto

Keyword(s):

Pulmonary Emboli

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Higher Incidence of Deep Venous Thrombosis and Pulmonary Emboli Among Coronavirus Disease 2019 (COVID-19) Positive Patients: A Multisite Healthcare System Experience

Journal of Vascular Surgery Venous and Lymphatic Disorders ◽

10.1016/j.jvsv.2020.12.013 ◽

2021 ◽

Vol 9 (2) ◽

pp. 539

Author(s):

Camila Franco Mesa ◽

Young Erben ◽

Michelle Lin ◽

Andrew Meltzer ◽

Melanie Greenway ◽

...

Keyword(s):

Venous Thrombosis ◽

Deep Venous Thrombosis ◽

Healthcare System ◽

Pulmonary Emboli

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Early appearance of echo-contrast simulating an intracardiac shunt in a patient with liver cirrhosis and intrapulmonary shunting

Journal of the American Society of Echocardiography ◽

10.1067/mje.2002.116827 ◽

2002 ◽

Vol 15 (4) ◽

pp. 379-381 ◽

Cited By ~ 14

Author(s):

Tasneem Z Naqvi ◽

Tomoo Nagai ◽

Shaul Atar ◽

Robert J Siegel

Keyword(s):

Liver Cirrhosis ◽

Intracardiac Shunt ◽

Early Appearance ◽

Intrapulmonary Shunting

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Familial thrombophilia associated with fibrinogen Paris V: Dusart syndrome

Blood ◽

10.1182/blood.v96.3.1191 ◽

2000 ◽

Vol 96 (3) ◽

pp. 1191-1193 ◽

Cited By ~ 15

Author(s):

Takashi Tarumi ◽

Danko Martincic ◽

Anne Thomas ◽

Robert Janco ◽

Mary Hudson ◽

...

Keyword(s):

Pulmonary Embolism ◽

Venous Thromboembolism ◽

Early Onset ◽

Family Members ◽

Initial Presentation ◽

Pulmonary Emboli ◽

Common Cause ◽

History Of ◽

Prophylactic Anticoagulation ◽

Fibrin Clots

Abstract We report on a family with a history of venous thromboembolism associated with fibrinogen Paris V (fibrinogen A-Arg554→Cys). Ten members experienced thrombotic events, including 4 with fatal pulmonary emboli. Pulmonary embolism was the presenting feature in 4. Those with the mutation and a history of thrombosis had somewhat higher fibrinogen concentrations than those with the mutation and no thrombosis (294 ± 70 mg/dL vs 217 ± 37 mg/dL, respectively). The Paris V mutation consistently caused a prolongation of the reptilase time, and fibrin clots containing the abnormal fibrinogen were more translucent than normal clots. Given the early onset of symptoms and the initial presentation with pulmonary embolism in some family members, it was justifiable to offer prophylactic anticoagulation with warfarin to carriers of the mutation. Fibrinogen Paris V has now been reported in 4 apparently unrelated families, indicating that it is a relatively common cause of dysfibrinogenemia-associated thrombosis.

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