A COMPARISON OF THE PLASMA IRON, IRON-BINDING CAPACITY, STERNAL MARROW IRON AND OTHER METHODS IN THE CLINICAL EVALUATION OF IRON STORES

1958 ◽  
Vol 48 (1) ◽  
pp. 60 ◽  
Keyword(s):  
Clinical Evaluation ◽  
Binding Capacity ◽  
Iron Binding ◽  
Iron Stores ◽  
Plasma Iron ◽  
Iron Iron ◽  
Iron Binding Capacity

Iron preparations for children

1966 ◽  
Vol 4 (3) ◽  
pp. 9-11
Keyword(s):  
Bone Marrow ◽  
Iron Deficiency ◽  
Blood Smear ◽  
Binding Capacity ◽  
Iron Binding ◽  
Iron Stores ◽  
Plasma Iron ◽  
Hypochromic Anaemia ◽  
Iron Binding Capacity

We have discussed iron preparations for adults in earlier articles;1 much of the information applies equally to children. Iron is not a ‘tonic’ and should be given only to prevent or correct iron deficiency. Estimation of the haemoglobin and inspection of a blood smear are the minimum investigations necessary before iron is prescribed in therapy. When deficiency is suspected in the absence of hypochromic anaemia, plasma iron and iron-binding capacity should be estimated and/or the bone marrow examined for haemosiderin crystals which disappear when iron stores are depleted.

PLASMA IRON AND IRON-BINDING CAPACITY

The Lancet ◽  
1975 ◽  
Vol 305 (7919) ◽  
pp. 1293
Author(s):  
Terry Hamblin
Keyword(s):  
Binding Capacity ◽  
Iron Binding ◽  
Plasma Iron ◽  
Iron Binding Capacity

Plasma iron and transferrin iron-binding capacity evaluated by colorimetric and immunoprecipitation methods.

1987 ◽  
Vol 33 (2) ◽  
pp. 273-277 ◽  
Author(s):  
H A Huebers ◽  
M J Eng ◽  
B M Josephson ◽  
N Ekpoom ◽  
R L Rettmer ◽  
...  
Keyword(s):  
Isotope Dilution ◽  
Binding Capacity ◽  
Colorimetric Method ◽  
Isotope Dilution Method ◽  
Dilution Method ◽  
Iron Binding ◽  
Plasma Iron ◽  
Excess Iron ◽  
Iron Deficient ◽  
Iron Binding Capacity

Abstract We evaluated plasma iron (PI) and total iron-binding capacity (TIBC) or transferrin in normal individuals and in patients with iron imbalance. The standard colorimetric measurements of PI and TIBC and the standard isotope-dilution measurement of TIBC were compared with an immunoprecipitation method and also with immunoelectrophoresis of transferrin. PI concentrations as measured by the standard and immunoprecipitation methods agreed closely for all individuals except those with saturated transferrin, where nontransferrin iron increased the results in the standard assay. This excess iron in saturated plasma may be derived from either free iron or iron-bearing ferritin. There were also differences in TIBC between the two methods. Iron-deficient sera gave higher values for transferrin when measured by immunoelectrophoresis. Unsaturated iron-binding capacity was increased in the isotope-dilution method in some iron-saturated plasma, compounding errors when added to erroneously high PI values to compute TIBC. Perhaps some exchange of iron occurred between added iron and transferrin iron in the isotope-dilution method. These measurements confirm the accuracy of the standard colorimetric method of measuring PI and TIBC except in iron-saturated plasma. However, the greater specificity of a polyclonal immunoprecipitation method of measuring PI and TIBC makes it particularly useful in differentiating transferrin-bound iron from nontransferrin iron.

Transferrin Types, Iron-Binding Capacity and Body Iron Stores

1993 ◽  
Vol 43 (6) ◽  
pp. 337-341 ◽  
Author(s):  
C. Sikström ◽  
L. Beckman ◽  
G. Hallmans ◽  
K. Asplund
Keyword(s):  
Binding Capacity ◽  
Iron Binding ◽  
Body Iron ◽  
Iron Stores ◽  
Iron Binding Capacity

PLASMA-IRON AND IRON-BINDING CAPACITY

The Lancet ◽  
1975 ◽  
Vol 305 (7917) ◽  
pp. 1191
Author(s):  
Adam Turnbull ◽  
JoanF Zilva
Keyword(s):  
Binding Capacity ◽  
Iron Binding ◽  
Plasma Iron ◽  
Iron Binding Capacity
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