scholarly journals Looking for breed differentiating SNP loci and for a SNP set for parentage testing in Mangalica

2013 ◽  
Vol 56 (1) ◽  
pp. 200-207 ◽  
Author(s):  
A. Zsolnai ◽  
G. Tóth ◽  
J. Molnár ◽  
V. Stéger ◽  
F. Marincs ◽  
...  

Abstract. The whole genome of Mangalica animals has been screened on the Illumina porcine chip giving the possibility (1) to replace the previously applied ten microsatellite markers by nine SNP loci to classify the Blond, Swallow-Belly and Red Mangalica individuals into three different breed groups (P>0.95); (2) to propose 54 SNP loci for parentage testing in Mangalica pigs where the exclusion probability is 0.999115 if one parent is known and the probability of identity is 1.54×10-23.

2020 ◽  
Vol 42 (2) ◽  
pp. 240
Author(s):  
Peter B. S. Spencer ◽  
Serina McConnell ◽  
Diana Prada ◽  
J. A. (Tony) Friend

The numbat (Myrmecobius fasciatus) is an endangered and peculiar marsupial with a diet that consists almost exclusively of termites. This study developed a parentage-testing system for numbats using microsatellite markers. Nineteen loci detected 143 alleles, with 4–13 alleles/locus and average expected heterozygosity of 77% (range 0.665–0.855). The total parentage exclusion probability was >0.9999 (given only the genotype of the offspring), >0.9999 for excluding a candidate parent from the parentage of an arbitrary offspring (given the genotype of the offspring and parent) and the probability of identity for full-sibs was 4.6×10–9. Overall, these microsatellites offer a simple and highly informative marker-set for parentage identification in numbats.


1999 ◽  
Vol 8 (3) ◽  
pp. 233-237 ◽  
Author(s):  
P. BREDBACKA ◽  
M.T. KOSKINEN

Informativeness of eleven microsatellite markers suggested for parentage control in cattle by the International Society for Animal Genetics (ISAG) was studied in Finnish Ayrshire and Holstein-Friesian populations. Calculations were based on a sample of 100 non-sib artificial insemination bulls. Assuming one known parent the nine loci suggested for routine testing exhibited exclusion probabilities of 99.84% in the Ayrshires and 99.91% in the Holstein-Friesians. The addition of markers INRA23 and TGLA53, recommended for further investigations, increased the attained values to 99.94% in Ayrshires and to 99.98% in Holstein-Friesians. The recommended core set of six microsatellites provided a combined exclusion probability of 98.25% in Ayrshires and 99.32% in Holstein-Friesians. Although the combined values were high in general, a relatively low level of polymorphism was detected in some instances.;


2012 ◽  
Vol 11 (2) ◽  
pp. 1217-1229 ◽  
Author(s):  
C.A. Souza ◽  
S.R. Paiva ◽  
C.M. McManus ◽  
H.C. Azevedo ◽  
A.S. Mariante ◽  
...  

2010 ◽  
Vol 42 (2) ◽  
pp. 225-226 ◽  
Author(s):  
D. Monies ◽  
N. Abu Al Saud ◽  
N. Sahar ◽  
B. F. Meyer

2010 ◽  
Vol 28 (4) ◽  
pp. 585-596 ◽  
Author(s):  
Haitao Li ◽  
Xun Chen ◽  
Yuan Yang ◽  
Jinsong Xu ◽  
Jianxun Gu ◽  
...  

2018 ◽  
Vol 6 (6) ◽  
pp. 642-650
Author(s):  
Vasu Arora ◽  
Neera Kapoor ◽  
Samar Fatma ◽  
Sarika Jaiswal ◽  
Mir Asif Iquebal ◽  
...  

2003 ◽  
Vol 65 (9) ◽  
pp. 1003-1005 ◽  
Author(s):  
Shigehisa TSUMAGARI ◽  
Yasushi ICHIKAWA ◽  
Hiroshi TORIUMI ◽  
Kakashi ISHIHAMA ◽  
Mitsuo MORITA ◽  
...  

2001 ◽  
Vol 32 (1) ◽  
pp. 52-52 ◽  
Author(s):  
R. Achmann ◽  
T. Huber ◽  
B. Wallner ◽  
P. Dovc ◽  
M. Müller ◽  
...  

2008 ◽  
Vol 25 (3) ◽  
pp. 175-180 ◽  
Author(s):  
Kei Kitahara ◽  
Shigeyuki Kawa ◽  
Yoshihiko Katsuyama ◽  
Takeji Umemura ◽  
Yayoi Ozaki ◽  
...  

Alcohol abuse is one of the most common risk factor for chronic pancreatitis, but the underlying pathophysiological mechanisms remain unclear. The aim of this study was to identify genes that contribute to susceptibility or resistance for alcoholic chronic pancreatitis by screening the whole genome. Sixty-five patients with alcoholic chronic pancreatitis (63 men and 2 women, mean age 55.2 years) and 99 healthy Japanese controls were enrolled in this study. This was an association study using 400 polymorphic microsatellite markers with an average spacing of 10.8 cM distributed throughout the whole genome. This search revealed 10 candidate susceptibility regions and 5 candidate resistant regions throughout the genome. No specific microsatellite markers were detected in association with previously reported susceptibility genes for chronic pancreatitis, such asPRSS1, PRSS2, CTRC, SPINK1, CFTR, ALDH2, and CYP2E1. Among the statistically significant markers,D15S1007on chromosome 15q14 showed strong evidence for disease susceptibility (70.8% vs. 35.1%,Pc= 0.0001). Within 500 kb of D15S1007, several genes were candidate genes for susceptibility, includingFMN1, DKFZP686C2281, LOC440268, RYR3, and AVEN, This study identified 10 candidate susceptibility and 5 candidate resistant regions that may contain genes involved in ACP pathogenesis.


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