scholarly journals Numerical Investigation of Interaction between Saccular Abdominal Aortic Aneurysms and Arterial Bifurcations

2021 ◽  
Vol 25 (3) ◽  
pp. 209-224
Author(s):  
Kadhum Audaa Jehhef ◽  
◽  
Ali Jalal Ali ◽  
Keyword(s):  
Flow Velocity ◽  
Vascular System ◽  
Abdominal Aortic Aneurysms ◽  
Rigid Wall ◽  
Aortic Aneurysms ◽  
Ansys Fluent ◽  
Steady State Condition ◽  
Numerical Predictions ◽  
Real Model ◽  
Abdominal Aortic

In order to fully understand the interaction between the Abdominal Aortic Aneurysms (AAAs) and the arterial bifurcations interface it is important to attain more detailed information on blood hemodynamics stresses by using an accurate and real model of the vascular system of the human. In this study, a computer simulation, which integrates dinically acquired of 73-year-old male patient with saccular AAA MR angiograms image is considered. The numerical predictions for 2D of two models (with and without saccular AAA) – axisymmetric, rigid wall Newtonian and non-Newtonian Carreau blood model are presented. The finite volume method performed by ANSYS-Fluent Package was used to model this problem. The blood hemodynamics is considered as steady state condition in two values of Reynolds numbers of laminar flow condition. Blood hemodynamics is calculated for an improved set of dimensionless values pointer parameters include the pressure dimensionless, dimensionless Wall Shear Stress (WSS) and flow velocity. The results show that at the turbulent flow, velocity is with highest fluctuation profile and generate some vortices near the inner wall of AAA. The highest WSS levels are obtained downstream of AAA and at bifurcation apex. The presence of AAA in flow path will increase blood velocity of the distal by 35% for laminar and about 42% for turbulent. Finally, the velocity profile was compared with previous literature and give good agreement at the same computational condition.

Abstract 306: Murine Abdominal Aortic Aneurysms Demonstrate Heterogeneous Growth and Remodelling by High-frequency Ultrasound

2016 ◽  
Vol 36 (suppl_1) ◽  
Author(s):  
Evan H Phillips ◽  
Paolo Di Achille ◽  
Matthew R Bersi ◽  
Jay D Humphrey ◽  
Craig J Goergen
Keyword(s):  
Blood Flow ◽  
Flow Velocity ◽  
Blood Flow Velocity ◽  
High Frequency ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
High Frequency Ultrasound ◽  
True Lumen ◽  
Abdominal Aortic ◽  
Frequency Ultrasound

In vivo imaging of vascular disease models has been largely underutilized, but it can greatly benefit cardiovascular research. An improved understanding of the development of the angiotensin II (AngII) apolipoprotein E knockout model of abdominal aortic aneurysms (AAAs) could help patients with this life-threatening disease. The objective of this study was to investigate the early hemodynamic, biomechanical, and volumetric changes in AngII AAAs using high-frequency ultrasound. Five male apolipoprotein E-deficient C57BL/6J mice were subcutaneously implanted with AngII-loaded miniosmotic pumps (1000 ng/kg/min) and screened for appearance of AAAs. We acquired imaging data of the morphology, pulsatility, and blood flow profiles in newly formed AAAs over 7 days. We found that biomechanical and hemodynamic changes occurred during initial AAA formation alongside an increase in AAA volume. Average AAA volume increased by 140±24% between baseline and AAA diagnosis, while true lumen volume decreased by 46±12% due to formation of a focal dissection. The resulting intramural thrombus evolved in shape and volume but with variability between animals. Regional differences in blood flow velocity were apparent down the length of the largest AAAs and mean blood flow velocity significantly increased by 150±42% upon initial aortic expansion and true lumen narrowing. Mean velocity decreased over 7 days as the total AAA volume increased. Circumferential cyclic strain also significantly decreased upon initial aortic expansion and remained reduced, indicating the AAAs had stiffened vessel walls with initial aortic expansion. We are also exploring the heterogeneity of this AAA development using computational pulsatile flow models built from these ultrasound datasets. These models can provide information on site-specific changes in wall shear stress and oscillatory shear index, which are potentially predictive metrics for intramural thrombus formation and AAA growth.

scholarly journals ACCESS SITES TO VASCULAR SYSTEM FOR ENDOVASCULAR ABDOMINAL AORTIC ANEURYSMS REPAIR

2006 ◽  
Vol 150 (1) ◽  
pp. 155-163 ◽  
Author(s):  
Petr Utikal ◽  
Martin Koecher ◽  
Petr Bachleda ◽  
Jirina Koutna ◽  
Petr Drac ◽  
...  
Keyword(s):  
Vascular System ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

Ruptured abdominal aortic aneurysms: Clinical presentation in Auckland 1993-1997

2001 ◽  
Vol 71 (6) ◽  
pp. 341-344
Author(s):  
Johanna Rose ◽  
Ian Civil ◽  
Timothy Koelmeyer ◽  
David Haydock ◽  
Dave Adams
Keyword(s):  
Clinical Presentation ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic ◽  
Ruptured Abdominal Aortic Aneurysms

Current evidence and prospects for medical treatment of abdominal aortic aneurysms

VASA ◽  
2005 ◽  
Vol 34 (4) ◽  
pp. 217-223 ◽  
Author(s):  
Diehm ◽  
Schmidli ◽  
Dai-Do ◽  
Baumgartner
Keyword(s):  
Abdominal Aortic Aneurysm ◽  
Aortic Aneurysm ◽  
Medical Treatment ◽  
Endovascular Treatment ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Current Evidence ◽  
Significant Morbidity ◽  
Abdominal Aortic ◽  
Risk Of Rupture

Abdominal aortic aneurysm (AAA) is a potentially fatal condition with risk of rupture increasing as maximum AAA diameter increases. It is agreed upon that open surgical or endovascular treatment is indicated if maximum AAA diameter exceeds 5 to 5.5cm. Continuing aneurysmal degeneration of aortoiliac arteries accounts for significant morbidity, especially in patients undergoing endovascular AAA repair. Purpose of this review is to give an overview of the current evidence of medical treatment of AAA and describe prospects of potential pharmacological approaches towards prevention of aneurysmal degeneration of small AAAs and to highlight possible adjunctive medical treatment approaches after open surgical or endovascular AAA therapy.

Statin therapy for patients with abdominal aortic aneurysms

VASA ◽  
2012 ◽  
Vol 41 (1) ◽  
pp. 3-4
Author(s):  
Diehm ◽  
Diehm ◽  
Dick
Keyword(s):  
Statin Therapy ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Abdominal Aortic

Endovascular management of ruptured abdominal aortic aneurysms and acute aortic dissections

VASA ◽  
2019 ◽  
Vol 48 (1) ◽  
pp. 35-46
Author(s):  
Stephen Hofmeister ◽  
Matthew B. Thomas ◽  
Joseph Paulisin ◽  
Nicolas J. Mouawad
Keyword(s):  
Abdominal Aortic Aneurysms ◽  
Rapid Identification ◽  
Aortic Aneurysms ◽  
Endovascular Interventions ◽  
Current State ◽  
Technological Advances ◽  
Abdominal Aortic ◽  
Ruptured Abdominal Aortic Aneurysms ◽  
Vascular Emergencies ◽  
Aortic Dissections

Abstract. The management of vascular emergencies is dependent on rapid identification and confirmation of the diagnosis with concurrent patient stabilization prior to immediate transfer to the operating suite. A variety of technological advances in diagnostic imaging as well as the advent of minimally invasive endovascular interventions have shifted the contemporary treatment algorithms of such pathologies. This review provides a comprehensive discussion on the current state and future trends in the management of ruptured abdominal aortic aneurysms as well as acute aortic dissections.

Stents for the Treatment of Aortic Aneurysms

1999 ◽  
Vol 82 (S 01) ◽  
pp. 171-175 ◽  
Author(s):  
D. Ebert ◽  
M. Langer ◽  
P. Uhrmeister
Keyword(s):  
Endovascular Treatment ◽  
Endovascular Repair ◽  
Abdominal Aortic Aneurysms ◽  
Aortic Aneurysms ◽  
Imaging Modalities ◽  
Exclusion Criteria ◽  
Multicenter Studies ◽  
Abdominal Aortic ◽  
First Results

SummaryThe endovascular treatment of abdominal aortic aneurysms has generated a great deal of interest since the early 1990s, and many different devices are currently available. The procedure of endovascular repair has been evaluated in many institutions and the different devices are compared. The first results were encouraging, but complications like endoleak, dislocation or thrombosis of the graft occurred. By the available devices the stent application is only promising, if the known exclusion criteria are strictly respected. Therefore a careful preinterventional assessment of the patient by different imaging modalities is necessary. As the available results up to now are preliminary and the durability of the devices has to be controlled, multicenter studies are required to improve the devices and observe their long- term success in the exclusion of abdominal aortic aneurysms.

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