scholarly journals Analyzing the Effects of Demographic Differences on Patient Outcomes Following Non-pyogenic Intracranial Venous Thrombosis

Cureus ◽  
2021 ◽  
Author(s):  
Kevin F Labagnara ◽  
Jessie Birnbaum ◽  
Santiago R Unda ◽  
David J Altschul
2020 ◽  
pp. 000313482095485
Author(s):  
Joseph A. Lewcun ◽  
Rahima Khatun ◽  
Steven Allen ◽  
Joshua P. Hazelton ◽  
Amanda Cooper

Background Mesenteric venous thrombosis (MVT) is typically associated with poor prognosis. Although prophylactic antibiotics are sometimes given with the intent of limiting bacterial luminal load and translocation in patients with MVT, this approach has not been universally adopted. The aim of this study is to analyze whether utilizing antibiotics empirically in those with MVT improves patient outcomes and survival when compared to those who do not receive empiric antibiotics. Methods A retrospective review of patients admitted with MVT between 2002 and 2019 at a single academic institution was performed. Demographics and rates of mortality need for bowel resection, readmission, and Clostridium difficile ( C. diff) infection were compared between patients treated with empiric antibiotics and patients not treated with antibiotics. Results Eighty-three patients (mean age 64.5 years and 55.4% male) who were admitted for MVT were included. Empiric antibiotics were utilized in 53% (n = 44) of MVT patients while 47% (n = 39) received supportive treatment without empiric antibiotics. Death occurred in 4 patients treated with antibiotics and 6 patients treated without antibiotics (9.1% vs. 15.3%, P = .50). Readmissions occurred in 12 patients (27.3%) treated with antibiotics and 10 patients (25.6%) not treated with antibiotics (27.3% vs. 25.6%, P = .87). C. diff infection occurred in 6 patients treated with antibiotics and in no patients not treated with antibiotics (13.6% vs. 0%, P = .03). Conclusions Empiric antibiotic usage may not improve rates of mortality or hospital readmission in patients with MVT and may unnecessarily expose patients to an increased risk of C. diff infection.


2020 ◽  
Vol 158 (6) ◽  
pp. S-1556-S-1557
Author(s):  
Joseph A. Lewcun ◽  
Rahima Khatun ◽  
Steven Allen ◽  
Amanda Cooper

Medicina ◽  
2019 ◽  
Vol 55 (11) ◽  
pp. 715 ◽  
Author(s):  
Gavrilova ◽  
Bandere ◽  
Rutkovska ◽  
Šmits ◽  
Mauriņa ◽  
...  

Background and Objectives: A particular problem in cardiology is poor adherence to pharmacological treatment among patients with hypertension. It is known that approximately half of these patients do not use their medications as prescribed by their doctor. Patients may choose not to follow the doctor’s recommendations and regularly do not control their blood pressure, owing to many factors. A convenient method for measuring the level of adherence is the Morisky Medication Adherence Scale, which also provides insight into possible remedies for low adherence. We investigated their therapy, knowledge about the disease and its control, and demographic differences to assess the adherence of patients with hypertension. Materials and Methods: This was a cross-sectional observational study. Data were collected through a survey of 12 pharmacies in Latvia. The study involved 187 participants with hypertension. Results: The prevalence of non-adherence was 46.20% in Latvia. The oldest patients were the most adherent (p = 0.001, β = 0.27). The higher the self-rated extent from 0 to 10, to which the patient takes their antihypertensives exactly as instructed by their physician, the higher the level of adherence (p < 0.0001, β = 0.38), where at “0”, the patient does not follow physician instructions at all, and at “10”, the patient completely follows the physician’s instructions. Non-adherent patients tend to assess their medication-taking behavior more critically than adherent patients. The longer the patient is known to suffer from hypertension, the more adherent he or she is (p = 0.014, β = 0.19). Conclusions: Medication non-adherence among patients with hypertension is high in Latvia. Further investigations are needed to better understand the reasons for this and to establish interventions for improving patient outcomes.


2018 ◽  
Vol 154 (6) ◽  
pp. S-711
Author(s):  
Evangelos Kalaitzakis ◽  
Maria Baldursdottir ◽  
Berglind Magnusdottir ◽  
Margret Arnardottir ◽  
Arnar S Agustsson ◽  
...  

2020 ◽  
Vol 22 ◽  
pp. 100797
Author(s):  
Jessie A. Birnbaum ◽  
Kevin F. Labagnara ◽  
Santiago R. Unda ◽  
David J. Altschul

2016 ◽  
Vol 39 ◽  
Author(s):  
Till Bergmann ◽  
Rick Dale ◽  
Gary Lupyan

AbstractThe Now-or-Never bottleneck has important consequence for understanding why languages have the structures they do. However, not addressed by C&C is that the bottleneck may interact with who is doing the learning: While some languages are mostly learned by infants, others have a large share of adult learners. We argue that such socio-demographic differences extend and qualify C&C's thesis.


2020 ◽  
Vol 5 (2) ◽  
pp. 439-456
Author(s):  
Jenny L. Pierce

Purpose This review article provides an overview of autoimmune diseases and their effects on voice and laryngeal function. Method A literature review was conducted in PubMed. Combinations of the following keywords were used: “autoimmune disease and upper airway,” “larynx,” “cough,” “voice,” “dysphonia,” and “dyspnea.” Precedence was given to articles published in the past 10 years due to recent advances in this area and to review articles. Ultimately, 115 articles were included for review. Results Approximately 81 autoimmune diseases exist, with 18 of those highlighted in the literature as having laryngeal involvement. The general and laryngeal manifestations of these 18 are discussed in detail, in addition to the clinical implications for a laryngeal expert. Conclusions Voice, breathing, and cough symptoms may be an indication of underlying autoimmune disease. However, these symptoms are often similar to those in the general population. Appropriate differential diagnosis and timely referral practices maximize patient outcomes. Guidelines are provided to facilitate correct diagnosis when an autoimmune disease is suspected.


2001 ◽  
Vol 33 (1) ◽  
pp. 138-138
Author(s):  
Jane H. Barnsteiner
Keyword(s):  

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