scholarly journals HIF-1 a and GLUT-1 Expression in Atypical Endometrial Hyperplasia, Type I and II Endometrial Carcinoma: A Potential Role in Pathogenesis

2016 ◽  
Author(s):  
Dalia Rifaat Al-Sharaky
Keyword(s):  
Endometrial Carcinoma ◽  
Endometrial Hyperplasia ◽  
Potential Role ◽  
Type I ◽  
Glut 1 ◽  
Atypical Endometrial Hyperplasia

Which surgical procedure for patients with atypical endometrial hyperplasia?

2005 ◽  
Vol 15 (1) ◽  
pp. 127-131 ◽  
Author(s):  
B. S. Karamursel ◽  
S. Guven ◽  
G. Tulunay ◽  
T. Kucukali ◽  
A. Ayhan
Keyword(s):  
Endometrial Carcinoma ◽  
Endometrial Hyperplasia ◽  
Menopausal Status ◽  
Endometrial Biopsy ◽  
Surgical Staging ◽  
Lymph Node Status ◽  
Atypical Endometrial Hyperplasia ◽  
Group I ◽  
Significant Difference ◽  
Group Ii

ObjectiveTo determine the occult coexistence of endometrial carcinoma in patients with atypical endometrial hyperplasia and to compare histological prognostic factors according to lymph node status in occult endometrial carcinoma.Materials and MethodsTwo hundred and four patients from two referral centers (during the period 1990–2003) who were operated on within 1 month of endometrial biopsy for symptomatic endometrial hyperplasia without receiving any medical treatment were included retrospectively. Patients having preoperative endometrial biopsy results of concomitant endometrial hyperplasia and carcinoma were excluded from the study. Fifty-six patients having atypia in preoperative biopsy (group I) were compared with 148 patients without atypia (group II). Chi-square and Mann–Whitney U-tests were used for statistical analyses.ResultsNo significant difference was observed between the two groups according to age or menopausal status. Patients in group II had significantly higher parity than patients in group I. In group I, 62.5% of the patients had endometrial carcinoma, 21.4% had endometrial hyperplasia, and 16.1% had normal endometrium in hysterectomy specimens. In group II, the percentages were 5.4, 38.5, and 56.1%, respectively. Complete surgical staging was performed in 20 patients. Four patients had metastatic lymph nodes. All of them had grade 2 tumors with lymphovascular space involvement. Three of them had nonendometrioid tumors.ConclusionCareful intraoperative and preoperative evaluation of the endometrium must be the sine qua non for patients with atypical endometrial hyperplasia. It is reasonable to do frozen section at the time of hysterectomy for atypical endometrial hyperplasia, and if grade 2/3 of nonendometriod cancer with lymphovascular space involvement is found, complete surgical staging should be performed.

Young Nulliparous Female with Continous Vaginal Bleeding: A Case of Atypical Endometrial Hyperplasia

2018 ◽  
Vol 3 (6) ◽  
Keyword(s):  
Endometrial Carcinoma ◽  
Vaginal Bleeding ◽  
Endometrial Hyperplasia ◽  
Definitive Treatment ◽  
Atypical Endometrial Hyperplasia ◽  
Dilatation And Curettage ◽  
One Year ◽  
Nulliparous Female ◽  
Secretory Endometrium ◽  
Continuous Bleeding

Mrs. XYZ 32 years of age, nulliparous presented in the OPD with complaint of continuous vaginal bleeding for 1 month. She had had Dx D & C twice previously for the same complaint one year ago. The two H/P reports showed Adenocarcinoma of the Uterus and repeat D & C one month later showed Secretory endometrium. Dilatation and curettage was done again on19. 03 2018 which showed Atypical Endometrial Hyperplasia (AEH). The couple was counseled and they opted for definitive treatment. TAH & BSO was done on 03.04 2018. Cut section showed thickened endometrium with no myometrium invasion. Conclusion: In patients with irregular or continuous bleeding P/V should be evaluated for AEH or Endometrial carcinoma.

scholarly journals PINCH Protein Expression in Normal Endometrium, Atypical Endometrial Hyperplasia and Endometrioid Endometrial Carcinoma

Chemotherapy ◽  
2010 ◽  
Vol 56 (4) ◽  
pp. 291-297 ◽  
Author(s):  
Hong-Zhen Zhang ◽  
Xue-Hui Li ◽  
Xia Zhang ◽  
Zhi-Yong Zhang ◽  
Ya-Li Meng ◽  
...  
Keyword(s):  
Protein Expression ◽  
Endometrial Carcinoma ◽  
Endometrial Hyperplasia ◽  
Normal Endometrium ◽  
Atypical Endometrial Hyperplasia ◽  
Endometrioid Endometrial Carcinoma

Concurrent endometrial carcinoma following hysterectomy for atypical endometrial hyperplasia

2010 ◽  
Vol 150 (1) ◽  
pp. 80-83 ◽  
Author(s):  
Ho-Suap Hahn ◽  
Yi-Kyeong Chun ◽  
Yong-Il Kwon ◽  
Tae-Jin Kim ◽  
Ki-Heon Lee ◽  
...  
Keyword(s):  
Endometrial Carcinoma ◽  
Endometrial Hyperplasia ◽  
Atypical Endometrial Hyperplasia
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