scholarly journals Giant Malignant Phyllodes Tumour of Breast- A Clinical Dilemma and Surgical Challenge

2021 ◽  
Author(s):  
Raghav Yelamanchi ◽  
Nikhil Gupta ◽  
Dhruv Gupta ◽  
CK Durga
Keyword(s):  
Pectoralis Major Muscle ◽  
Left Breast ◽  
High Index ◽  
Image Guided ◽  
Phyllodes Tumour ◽  
Benign Tumours ◽  
Clinical Dilemma ◽  
Phyllodes Tumours ◽  
High Index Of Suspicion ◽  
Malignant Phyllodes Tumour

Phyllodes tumour is an uncommon tumour of the breast. It is fibroepithelial in origin and mostly benign. Giant phyllodes tumours are described as tumours with size more than 10 cm and are extremely rare. Differentiating malignant and benign tumours pathologically is difficult and needs clinical judgement and high index of suspicion. A 50-year-old female presented with complaint of swelling in the left breast. On further evaluation, it was diagnosed as phyllodes tumour on biopsy. She underwent left mastectomy and excision of pectoralis major muscle due to clinical and radiological suspicion of malignancy. Postoperative histopathology report revealed malignant phyllodes tumour. Cases of giant phyllodes tumour should undergo adequate imaging and image guided biopsy with high index for suspicion for malignancy. They should be operated as per the principles of oncosurgery as there is a high probability of such huge tumours harboring malignancy.

scholarly journals Fibroadenoma in an operated case of malignant phyllodes tumour: a rare case report

2017 ◽  
Vol 4 (2) ◽  
pp. 792
Author(s):  
Iresh Shetty ◽  
Tushar Jadhav ◽  
Aditya Lad ◽  
Gaurav Batra ◽  
Ishant Rege ◽  
...  
Keyword(s):  
Frozen Section ◽  
Left Breast ◽  
Low Grade ◽  
Previous Surgery ◽  
Rare Presentation ◽  
Phyllodes Tumour ◽  
Rare Case Report ◽  
Single Disease Entity ◽  
Phyllodes Tumours ◽  
Malignant Phyllodes Tumour

Phyllodes tumours are rare fibroepithelial lesions that account for less than 1% of breast neoplasms. Displaying a broad range of clinical and pathological behaviour, phyllodes tumours should be regarded as a spectrum of fibroepithelial neoplasms rather than a single disease entity. We would like to present a rare presentation of fibroadenoma over site of a previously operated case of malignant phyllodes tumour. A 36 year old female came to OPD with complaints of lump in both breasts since 4 months. She gave history of previous surgery, i.e., left breast lumpectomy for which HPE report was suggestive of malignant phyllodes tumour. On examination, 3x2 cm, solitary, firm to hard, non-tender lump was felt in the junction of the upper outer and inner quadrant just below the scar of previous surgery and was not freely mobile and appeared fixed to the scar. Patient underwent excision of the lump with frozen section and final HPE report turning out to be fibroadenoma. Though diagnosis of malignant phyllodes tumour is not difficult, diagnosis of low grade phyllodes tumour and distinction from fibroadenoma on FNA is difficult due to overlapping features between the two lesions. Surgery remains the mainstay of treatment for patients with cystosarcoma phyllodes, extent of surgery been controversial, and continues to evolve. Incidence of fibroadenoma occurring at the previous operated site of malignant phyllodes tumour is very rare with no known previous documentation of such a case.

scholarly journals Malignant Phyllodes Tumour with Rhabdomyosarcomatous Differentiation: A Rare Phenomenon

2021 ◽  
Author(s):  
Kusum Yadav ◽  
Jitendra Singh Nigam ◽  
Anshul Singh ◽  
Vatsala Misra
Keyword(s):  
Rare Tumour ◽  
Complete Excision ◽  
Eosinophilic Cytoplasm ◽  
Phyllodes Tumour ◽  
Abundant Eosinophilic Cytoplasm ◽  
One Year ◽  
Phyllodes Tumours ◽  
The Right ◽  
Pleomorphic Cells ◽  
Malignant Phyllodes Tumour

Phyllodes tumour is a rare tumour of the breast constituting less than 1% of all breast tumours. Malignant Phyllodes Tumour (MPT) accounts for only 10-30% of all phyllodes tumours. Heterologous sarcomatous differentiation in a MPT is an infrequent phenomenon, with the cases reported showing differentiation mostly towards liposarcoma, fibrosarcoma, angiosarcoma, osteosarcoma, or chondrosarcoma. MPTs with rhabdomyosarcomatous differentiation are scarcely seen with only three confirmed cases documented till date to the best of the knowledge after a thorough search of literature. Here, authors present a case of 45-year-old female who presented with a well-defined rapidly growing lump in the right breast for last one year. A core needle biopsy performed showed a sarcomatous picture on histology. Complete excision was subsequently done. On microscopy, most of the areas showed fibrosarcomatous changes with frequent mitoses. Some of the foci showed large pleomorphic cells in diffuse sheets that were polygonal with densely abundant eosinophilic cytoplasm and vesicular nucleus with prominent nucleoli (rhabdomyoblasts). Myogenin was diffusely positive on Immunohistochemistry (IHC). A diagnosis of MPT with rhabdomyosarcomatous differentiation was made. This case is reported here for its unusual presentation and to make pathologists aware of this rare heterologous differentiation of MPT.

Aggressive malignant phyllodes tumor of breast with omental metastases – A case report

2021 ◽  
Vol 40 (4) ◽  
pp. 287-291
Author(s):  
B. Rajkrishna ◽  
Rajesh Balakrishnan ◽  
Mithun Raam ◽  
A. Santhosh Raj ◽  
Patricia Sebastian ◽  
...  
Keyword(s):  
Radical Mastectomy ◽  
Phyllodes Tumor ◽  
Distant Metastases ◽  
Left Breast ◽  
Adjuvant Radiation ◽  
Left Chest ◽  
Dismal Prognosis ◽  
Phyllodes Tumour ◽  
Flap Cover ◽  
Malignant Phyllodes Tumour

Distant metastasis from malignant Phyllodes tumour (PT) is rare. They generally metastasize to the lung, bone, pleura, and liver. We present a very rare case of a 25-year-old woman with intraabdominal metastases from malignant phyllodes tumour of the breast. She presented with left breast lump and the biopsy was Phyllodes tumour. She underwent a two staged surgery; left modified radical mastectomy followed by left latissimus dorsi musculocutaneous flap cover. She received adjuvant radiation therapy to left chest wall. Following which she developed intrabdominal mass which was proven to be metastasis from Phyllodes tumour. She was then advised palliative chemotherapy. Malignant Phyllodes with distant metastases has a dismal prognosis. We propose it is preferable to have a CT Thorax and Abdomen as a staging workup for patients with malignant PT to identify those with poor prognosis.

scholarly journals Phyllodes tumour of the labia minora

2019 ◽  
Vol 12 (11) ◽  
pp. e229917 ◽  
Author(s):  
Dennis T Fujii ◽  
Coleen A Korzen ◽  
Tiffany C Levine ◽  
Ryan J Heitmann
Keyword(s):  
Differential Diagnosis ◽  
Operating Room ◽  
Pathological Examination ◽  
Operative Hysteroscopy ◽  
Labia Minora ◽  
Rare Tumours ◽  
Phyllodes Tumour ◽  
Benign Tumours ◽  
Phyllodes Tumours ◽  
Preoperative Examination

A 33-year-old woman presented for a preoperative examination prior to an upcoming operative hysteroscopy. During the examination, a firm 1 cm mass in her right labia minora was noted. The mass was excised in the operating room without difficulty. Pathological examination revealed a benign phyllodes tumour of the vulva. Phyllodes tumours are uncommon fibroepithelial tumours primarily found in the breast although rarely may present as a vulvar lesion. Phyllodes tumours of the vulva are rarely reported in the literature, with only 17 previously reported cases. This case represents the first reported case of a phyllodes tumour occurring in the labia minora. While most of these tumours are benign, it is important to keep these and other rare tumours in the differential diagnosis of vulvar masses. Even with benign tumours, continued surveillance for recurrence should be performed.

scholarly journals BORDERLINE PHYLLODES TUMOUR

2015 ◽  
Vol 1 (2) ◽  
Author(s):  
Saima Haider ◽  
Misbah Tasleem
Keyword(s):  
Multidisciplinary Approach ◽  
Breast Tumour ◽  
Left Breast ◽  
Breast Ultrasound ◽  
High Rate ◽  
Excision Biopsy ◽  
Breast Masses ◽  
Key Words Breast ◽  
Phyllodes Tumour ◽  
Phyllodes Tumours

We report a case of 40-year-old woman with a painful lump in the left breast. Mammography revealed a suspicious mass ACR BI-RADS category 4a. Excision biopsy revealed borderline phyllodes tumour. Our case highlights the signi cance of multidisciplinary approach in managing benign breast masses such as phyllodes tumours which have malignant potential and a high rate of recurrence. Key words: Breast ultrasound, mammography, phyllodes breast tumour 

scholarly journals Angiosarcoma of the Scalp Presenting in Association With Borderline Malignant Phyllodes Tumour of the Breast

Sarcoma ◽  
2003 ◽  
Vol 7 (3-4) ◽  
pp. 173-176 ◽  
Author(s):  
Susan V. Harden ◽  
Richard Y. Ball ◽  
Adrian N. Harnett
Keyword(s):  
Elderly Woman ◽  
Primary Tumour ◽  
Surgical Removal ◽  
P53 Mutations ◽  
Rare Tumour ◽  
Phyllodes Tumour ◽  
Scalp Lesion ◽  
Phyllodes Tumours ◽  
Mesenchymal Tumours ◽  
Malignant Phyllodes Tumour

Phyllodes tumours and angiosarcoma are both rare mesenchymal tumours. There are no reports of their coexistence in the literature except in families with germline p53 mutations. Here we report a case of an elderly woman who developed an extensive angiosarcoma of the scalp nearly 4 years after surgical removal of a borderline malignant phyllodes tumour of the breast. The scalp lesion was initially thought more likely to be a metastasis of her first rare tumour than a second equally rare primary tumour, but histologically this was not the case. The case and the literature are discussed.

REDUCTION MAMMOPLASTY FOR BENIGN PHYLLODES TUMOUR IN AN ADOLESCENT FEMALE

2021 ◽  
pp. 48-49
Author(s):  
B. Santhi ◽  
D. Arun ◽  
Subhashini. A
Keyword(s):  
Reduction Mammoplasty ◽  
Adolescent Female ◽  
Adolescent Women ◽  
Female Breast ◽  
Areola Complex ◽  
Phyllodes Tumour ◽  
Aesthetic Aspect ◽  
Benign Tumours ◽  
The Aesthetic ◽  
Phyllodes Tumours

Phyllodes tumours are rare neoplasm of female breast especially among adolescent women. We present a case of 17 year old female patient present with large benign phyllodes tumour. The patient was treated with one stage excision with reduction mammoplasty. Symmetry of the breast contour and nipple areola complex position could be restored. Standard plastic surgery techniques like reduction mammoplasty might be applied in treating large benign tumours not compromising the aesthetic aspect of the breast.

scholarly journals Giant Phyllodes Tumour in a Postmenopausal Woman: A Case Report

2020 ◽  
Author(s):  
Kalaivani Vinayagam ◽  
C Satish ◽  
Abhishek Chaturvedi
Keyword(s):  
Left Breast ◽  
Split Thickness Skin Graft ◽  
Provisional Diagnosis ◽  
Median Size ◽  
Thickness Skin ◽  
Phyllodes Tumour ◽  
Simple Mastectomy ◽  
Post Menopausal ◽  
Phyllodes Tumours

Phyllodes Tumours (PT) of the breast are uncommon fibroepithelial lesions accounting for less than 1% of breast tumours. These tumours commonly occur in females during the fourth and fifth decade of life. They have a morphological resemblance to the intra-canalicular fibroadenoma. Their median size is around 4 cm, however if the size is more than 10 cm it’s called a giant phyllodes tumour accounting to less than 10% of phyllodes tumours. Clinically and histologically, they are difficult to be differentiated from fibroadenoma and a wide local excision is the mainstay of treatment. Hereby, Authors are reporting a case of giant phyllodes tumour in a 56-year-old post-menopausal female patient. She presented with a lump of 27×20 cm of two years duration occupying the entire left breast. Since,the lump had rapidly increased in size in the last six months of presentation, a clinical diagnosis of giant phyllodes tumour with malignant transformation was the provisional diagnosis. She underwent simple mastectomy with split-thickness skin graft. The final histopathology was reported as borderline phyllodes tumour and the patient was on a regular follow-up since the last 10 months.

Neurobrucellosis associated with feral swine hunting in the southern United States

2020 ◽  
Vol 13 (12) ◽  
pp. e238216
Author(s):  
Harry Ross Powers ◽  
Jared R Nelson ◽  
Salvador Alvarez ◽  
Julio C Mendez
Keyword(s):  
United States ◽  
At Risk ◽  
High Index ◽  
Southern United States ◽  
Endemic Country ◽  
Feral Swine ◽  
Neurological Sequelae ◽  
Initial Symptoms ◽  
The Usa ◽  
High Index Of Suspicion

Although uncommon, Brucella infection can occur outside the areas of high endemicity, such as the USA. In the southern USA, hunters of wild swine are at risk for brucellosis. We present a case of a patient with fever, headache and constitutional symptoms that were ongoing for 11 months. He was diagnosed with neurobrucellosis. The patient was treated successfully with intravenous ceftriaxone, oral doxycycline and oral rifampin therapy. He had persistent neurological sequelae after completing treatment. This case illustrates the high index of suspicion needed to diagnose neurobrucellosis in a non-endemic country because initial symptoms can be subtle. The disease can be treated successfully, but long-lasting neurological sequelae are common.

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