scholarly journals Adenomatoid Odontogenic Tumour Associated with Dentigerous Cyst: Case Report with Literature Review

Author(s):  
Pradipta Ramgonda Patil ◽  
Hirkani Attarde ◽  
Priyanka Prakash Kamble ◽  
Sangeeta Patankar ◽  
Gokul Sridharan

Adenomatoid Odontogenic Tumour (AOT) is a relatively uncommon benign odontogenic tumour composed of odontogenic epithelium in a variety of histoarchitectural patterns. Conventional AOT is predominantly seen in females in second decade of life exhibiting predilection for anterior region of maxilla. Very few cases of AOT associated with dentigerous cyst have been reported till date. The present case is unique associated with an impacted lower first premolar in the front region of the mandible of an 18-year-old female patient. The patient reported to the institute with gradually increasing swelling. The orthopantomogram revealed a unilocular radiolucency with displaced premolar. Histopathological examination confirmed 4×2.5×2 cm lesion in dimension, brownish black in colour, firm in consistency with a smooth surface grossly while cut surface revealed a cystic lumen with an impacted premolar embedded into the lining, cystic wall being nodular. Microscopic evaluation revealed a well encapsulated lesion with a thin 2-3 cell layered non keratinised stratified epithelial lining in patterns such as nests, rosette like structures and duct like structures. Thus the diagnosis of AOT arising from dentigerous cyst was confirmed. Patient's six month follow-up was uneventful. Literature search of similar cases with the review of hypothesised aetiopathogenesis is discussed in brief. The available data can help researchers resolve the uncertainty whether the AOT derived from dentigerous cyst could represent a distinct hybrid variety.

2021 ◽  
Vol 10 (11) ◽  
pp. 835-838
Author(s):  
Shreyas N. Shah ◽  
Falguni Patel ◽  
Vandana Shah

Adenomatoid odontogenic tumour, truly coined as one of the masters of disguise of orofacial pathologies, was first reported in the literature by Steen Lands.1 Philipson and Brin used the terminology adenomatoid odontogenic tumour for this pathology with its commonly accepted abbreviation AOT.2 Later on, adenomatoid odontogenic tumour (AOT) name was accepted by the World Health Organization (WHO) in 1971. In 2005, WHO revealed the histological variants of the adenomatoid odontogenic tumour and classified it as a tumour comprised of odontogenic epithelium showing various patterns in histopathologic view within a mature connective tissue stroma.3 It is seldom noticed neoplasm which comprises only 3 % of all the odontogenic tumours. It was commonly found in the maxilla with female predilection and mostly in association with impacted canines.4-6 Adenomatoid odontogenic tumour is an odontogenic epithelial tumour usually seen in females in their second decade of life. The tumour is slow growing in nature which eventually results in painless expansion of jaw. The maxilla is commonly affected than mandible. Being benign in nature, most of the AOT cases usually got treated with conservative surgical enucleation but the greater size of tumour can leave behind an oro-facial defect. To prevent such type of incident, it is important to diagnose them early and treat accordingly. Herewith, we are presenting a case report of adenomatoid odontogenic tumour of mandible in a male patient.


Author(s):  
Bose Surajit ◽  
Bhakta Ipsita ◽  
Karar Chandan Kumar ◽  
Singh Dharvind Kumar ◽  
Banerjee Abhishek

The separation of the follicle from around the crown of an unerupted tooth causes formation of dentigerous cyst. It may undergo metaplasia in several cases. In this case a 30 year old female patient reported with a history of dentigerous cyst with respect to impacted 48. The swelling started growing gradually causing facial asymmetry. On intraoral examination the swelling seem to extend from 48 to 46 region and cortical plates were expanded. The histopathological examination revealed the sample to be cystic ameloblastoma (mural variety). This paper sends a message that the potential of a cyst should never be understated, instead it must be kept in an observation or understanding the biological behavior over a course of time.


2019 ◽  
Vol 46 (3) ◽  
pp. 259-266
Author(s):  
Laura Han ◽  
Alison Downing ◽  
David Farr ◽  
Kaushik Dasgupta ◽  
Duncan Stewart

This case report aims to increase awareness of how an adenomatoid odontogenic tumour (AOT) can present in a similar fashion to a dentigerous cyst and the importance of accurate histopathological diagnosis. In this case, the AOT resulted in loss of the upper left permanent canine in a patient who already had a congenitally absent upper left second premolar, compromising the original orthodontic treatment plan.


2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Yi-Chun Lin ◽  
Hsiu-Ming Hsu ◽  
Chiang-Shin Liu ◽  
Kuo Yuan

Ameloblastic fibro-odontoma (AFO) predominantly occurs in the jaw bones of children and young adults. Extraosseous AFO is extremely rare. We describe a peripheral ameloblastic fibro-odontoma in the maxillary gingiva of a 3-year-old girl. The clinical appearance resembled fiery red reactive gingival lesions. The histopathological examination of the excised lesion showed small islands and cords of odontogenic epithelium with cellular myxoid stroma in the subepithelial tissue. The mass contained calcified material and an enamel-like deposit. Many small blood vessels appeared in the connective tissue surrounding the odontogenic epithelium. The immunohistochemical assays showed strong reactivity for amelogenin,β-catenin, CD44, and CD31 in the tissue sections. There was no recurrence after the 1-year follow-up. Because this lesion clinically resembles other nonneoplastic lesions and is very rare in gingiva, establishing a correct diagnosis is achieved only based on specific histological characteristics. Conservative excision of the tumor is the treatment of choice.


2015 ◽  
Vol 1 (2) ◽  
pp. 99
Author(s):  
Sayid Azhar ◽  
Maria Goereti ◽  
Soetji P Soetji P

Kista adalah penyebab pembengkakan kronis yang paling sering pada rahang dibandingkan tulang lain karena banyaknya sisa epitel odontogenik. Kista yang dibentuk dari epitel odontogenik merupakan yang terbanyak di rahang. Kista dentigerous merupakan kantung jaringan ikat yang berisi cairan dengan berbatas epitel skuamos berlapis yang terbentuk di sekitar mahkota gigi yang tidak erupsi atau dentikel. Kista ini sering disebut kista folikular karena hasil pembesaran folikel yang berasal dari akumulasi cairan antara epitel tereduksi dengan email gigi. Shear dan Spreight mengatakan bahwa etiologi terjadinya kista dentigerous bisa karena gigi impaksi. Seorang pasien laki – laki berusia 41 tahun dilaporkan datang ke klinik Bedah Mulut RSUP Dr. Sardjito dengan keluhan utama benjolan di bawah telinga kiri, tidak terasa sakit ukuran 4x3x3 cm muncul kurang lebih 8 bulan sebelumnya. Awalnya kecil kemudian membesar, pasien telah menjalani perawatan dari puskesmas dan tidak ada kemajuan. Penatalaksanaan kasus ini adalah enukleasi kista di bawah anestesi umum. Evaluasi dilakukan 4 bulan post operasi dan tidak ada tanda kambuh. Riwayat penyakit sistemik dan alergi obat tidak ada. ABSTRACT: Dentigerous Cyst Enucleation on Coronoid Mandibular Sinistra under General Anesthesia. Cyst is the most common caused of chronic swelling in the jaw compared to other bone as there are a lot of odontogenic epithelium. Cyst formed from odontogenic epithelium is the most encountered case found in dental practice. Dentigerous cyst is a sac formed of connective tissues filled with liquid and lined with stratified squamos epithelium border which was developed around un-erupted dental crown or denticle. This kind of cyst is also known follicular cyst on a reason that swelling follicle is derived from liquid accumulation between tooth enamel reductions with dental email. Shear and Spreight stated that impacted tooth is the ethiology of dentigerous cyst. We are reporting a case of41 year old man who came to Dr. Sardjito central hospital with chief complain of swelling under left ear, painless, 4x3x3 cm sized and increase within 8 months since its developed. The patient was treated in the Primary Health Care but no improvement reached. This case was managed with enucleated cyst under general anesthesia. No sign of recurrence after 3 months follow up and patient evaluation. No systemic disease and allergic symptom was found in this patient.


2007 ◽  
Vol 73 (1) ◽  
pp. 129-131 ◽  
Author(s):  
Cassiano Francisco Weege Nonaka ◽  
Lélia Batista de Souza ◽  
Lêda Bezerra Quinderé

Dental Update ◽  
2019 ◽  
Vol 46 (6) ◽  
pp. 561-564
Author(s):  
Nimit J Patel ◽  
Simon Toms ◽  
Fraser McDonald ◽  
Joanna Johnson ◽  
Louis McArdle

Unilocular radiolucent lesions of the dental hard tissues can present regularly, however they are impossible to diagnose definitively without appropriate imaging and histopathology. A case is reported that involves a 14-year-old that presented with a history of an unerupted maxillary first premolar. An initial Dental Panoramic Tomograph (DPT) did not identify any localized opacities and was diagnosed as a dentigerous cyst. A Cone Bean Computed Tomogram (CBCT) identified calcified opacities resulting in a re-evaluated radiological interpretation. With the help of a multidisciplinary approach, the removal of the benign lesion allowed orthodontic traction to extrude the tooth and for it to be brought into alignment. CPD/Clinical Relevance: This report highlights the importance of three-dimensional imaging as an adjunct to aid diagnosis and highlights the importance of multidisciplinary teams in the management of clinical challenges.


Author(s):  
Soorya Rao R. ◽  
Ravi K. S.

<p class="abstract"><span lang="EN-IN">We report a case of adenomatoid odontogenic tumor (AOT) in the maxilla in a boy aged 17 years. AOT is an odontogenic tumour arising from the enamel or dental lamina.  AOT is rare and it represents 3–7% of all odontogenic tumors. This lesion affects young girls and is associated with an impacted tooth, usually canine. This case is presented to highlight the presentation of the tumour in a male patient and in an uncommon site, the left upper 1st molar. Differentiating this benign tumor from other lesions is difficult before surgical management and histopathological examination is important in accurate diagnosis. </span><span lang="EN-IN"> </span></p>


Author(s):  
Leticia Gonçalves Ferreira

Resumo      O Ceratocisto Odontogênico (CO)é uma lesão intraóssea benigna de origem odontogênica, que surge a partir dos restos celulares da lâmina dental; apresenta predominância de acometimento em mandíbula, principalmente com envolvimento do corpo posterior e ramo de mandíbula. Os COs podem ser encontrados em pacientes desde a infância até a velhice, todavia, mais da metade dos casos são diagnosticados em pessoas entre 10 a 40 anos de idade, sendo sua prevalência em homens. Tal lesão cística exibe ao exame radiográfico uma área radio lúcida, com margens escleróticas frequentemente bem definidas. Histologicamente manifesta revestimento epitelial composto por uma camada uniforme de epitélio escamoso estratificado, geralmente com 6 ou 8 camadas de espessura, podem ser observados ainda pequenos cistos, cordões ou ilhas satélites de epitélio odontogênico na cápsula fibrosa, a qual é tipicamente delgada e friável. O objetivo do presente trabalho é relatar o caso clínico do paciente BSM,sexo masculino, feoderma, 22 anos de idade, ASA I, que compareceu ao ambulatório de Buco-Maxilo-Facial do Hospital Federal de Ipanema/RJapresentando uma lesão cística associada ao terceiro molar superior direito incluso. O tratamento consistiu na enucleação e curetagem da lesãoem ambiente hospitalar sob anestesia geral, sem presença de intercorrências. A peça cirúrgica foi encaminhada ao Laboratório de Biotecnologia Aplicada da Universidade Federal Fluminense (LABA-UFF) para exame anatomohistopatológico, sendo confirmado seu diagnóstico inicial de CO. O paciente recebeu alta no dia seguinte ao procedimento cirúrgico e segue em acompanhamento ambulatorial de 12 meses pela especialidade, sem presença clínica e imaginológica de recidiva da lesão. Palavras-chave: Ceratocisto Odontogênico; Enucleação; Maxila Abstract  The Odontogenic Keratocyst (CO) is a benign intraosseous lesion of odontogenic origin, which increases from the cellular remains of the dental membrane; it presents predominance of follow-up in the mandible, mainly with involvement of the posterior body and mandible branch. OCs can be found in patients from childhood to old age, however, more than half of the cases are diagnosed in people between 10 and 40 years of age, being its prevalence in men. Such a cystic lesion is detected in the radiographic examination of a radiolucent area, with sclerotic margins often quite reduced. Histologically, the epithelial lining composed of a uniform layer of stratified stratified epithelium, with 6 or 8 layers of thickness, can also be observed in small cysts, cords or satellite islands of odontogenic epithelium in the fibrous capsule, which is typically thin and friable. The objective of the present work is to relate the clinical case of BSM patient, male, feoderma, 22 years old, ASA I, who compared the cystic lesion associated with the included dental element to the buccomaxillofacial clinic of the Federal Hospital of Ipanema / RJ. Treatment consists of enucleation and curation of lesions in the hospital environment under general anesthesia, without the presence of complications. A surgical specimen was sent to the Laboratory of Applied Biotechnology by Universidade Federal Fluminense (LABA-UFF) for anatomo-histopathological examination, confirming its initial diagnosis of OC. The patient who was discharged the day after the medical procedure and is undergoing outpatient follow-up for 12 months, with no clinical and imaginative presence of injury recurrence. Keywords: Odontogenic Keratocyst; Enucleation; Maxilla


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