scholarly journals Adenomatoid Odontogenic Tumour - The Master of Disguise

2021 ◽  
Vol 10 (11) ◽  
pp. 835-838
Author(s):  
Shreyas N. Shah ◽  
Falguni Patel ◽  
Vandana Shah
Keyword(s):  
World Health ◽  
Odontogenic Tumour ◽  
Odontogenic Tumours ◽  
Facial Defect ◽  
Odontogenic Epithelium ◽  
Histological Variants ◽  
Epithelial Tumour ◽  
Adenomatoid Odontogenic Tumour ◽  
Health Organization ◽  
Slow Growing

Adenomatoid odontogenic tumour, truly coined as one of the masters of disguise of orofacial pathologies, was first reported in the literature by Steen Lands.1 Philipson and Brin used the terminology adenomatoid odontogenic tumour for this pathology with its commonly accepted abbreviation AOT.2 Later on, adenomatoid odontogenic tumour (AOT) name was accepted by the World Health Organization (WHO) in 1971. In 2005, WHO revealed the histological variants of the adenomatoid odontogenic tumour and classified it as a tumour comprised of odontogenic epithelium showing various patterns in histopathologic view within a mature connective tissue stroma.3 It is seldom noticed neoplasm which comprises only 3 % of all the odontogenic tumours. It was commonly found in the maxilla with female predilection and mostly in association with impacted canines.4-6 Adenomatoid odontogenic tumour is an odontogenic epithelial tumour usually seen in females in their second decade of life. The tumour is slow growing in nature which eventually results in painless expansion of jaw. The maxilla is commonly affected than mandible. Being benign in nature, most of the AOT cases usually got treated with conservative surgical enucleation but the greater size of tumour can leave behind an oro-facial defect. To prevent such type of incident, it is important to diagnose them early and treat accordingly. Herewith, we are presenting a case report of adenomatoid odontogenic tumour of mandible in a male patient.

scholarly journals A CLINICO-RADIOLOGICAL PRESENTATION OF ADENOMATOID ODONTOGENIC TUMOR OF MAXILA –A CASE REPORT

2020 ◽  
Author(s):  
Sadaksharam Jayachandran ◽  
Nivethitha N
Keyword(s):  
Case Report ◽  
Surgical Excision ◽  
Odontogenic Tumor ◽  
World Health ◽  
Adenomatoid Odontogenic Tumor ◽  
Odontogenic Tumour ◽  
Anterior Maxilla ◽  
Odontogenic Tumours ◽  
Epithelial Tumour ◽  
Adenomatoid Odontogenic Tumour

Adenomatoid Odontogenic Tumour (AOT) is odontogenic epithelial tumour, also known as pseudoadenoameloblastoma/adenoameloblastoma, which was described by Dreibaldt in 1907 [1]. The term “Adenomatoid odontogenic tumour” was proposed by Philipsen et al [2] indicating that it was not a variant of ameloblastoma. In the World Health Organization classification of odontogenic tumours established in 1971, AOT was mentioned as a mixed odontogenic neoplasm, an epithelial tumour with an inductive effect on the odontogenic mesenchyme [3].It represents 3–7% of all odontogenic tumours largely limited to younger patients and striking tendency to occur in anterior maxilla, and over 750 examples have been reported in the literature [4]. This case report presents a case of an Adenomatoid Odontogenic Tumour in the left maxillary anterior region which was diagnosed using radiographs and removed by surgical excision. KEYWORDS: Adenomatoid Odontogenic Tumor; Maxilla; Odontogenic tumor; Mixed radio opacity

scholarly journals Erupting Compound Odontome - A Case Report

2021 ◽  
Vol 10 (18) ◽  
pp. 1361-1364
Author(s):  
Shreyas N. Shah ◽  
Falguni Patel
Keyword(s):  
World Health Organization ◽  
World Health ◽  
Radiographic Evaluation ◽  
Dental Tissue ◽  
Odontogenic Tumours ◽  
Dental Tissues ◽  
Odontogenic Epithelium ◽  
Complex Odontoma ◽  
Health Organization ◽  
Compound Odontoma

Odontomas are asymptomatic, benign odontogenic tumours comprised of dental tissue. Most of the cases usually get detected on routine radiographic evaluation. Odontoma can be classified according to morphology in two different variants, compound odontoma showing anatomic similarity or miniature version of the tooth and complex odontoma having irregular masses with different type of dental tissues. Early detection of such type of silent lesion is mandatory to rule out certain silent but aggressive pathologies. Here, we present a case of erupting compound odontoma of maxillary area in 15-year-old male patient. Development of tooth is a result of complicated interaction between ectodermal and ecto mesenchymal tissue. Sometimes the remnants of such tissues are left behind in the jaw after development and eruption of tooth, which can become a source of development of odontogenic lesions later on.1 As revealed by World Health Organization (WHO), Odontogenic tumours can be classified in three different categories according to their histopathological form.2 1. Odontogenic tumours which develop from odontogenic epithelium without involvement of odontogenic ectomesenchyme, 2. Odontogenic tumours which develop from odontogenic epithelium with involvement of odontogenic ectomesenchyme, with or without formation of dental hard tissue and 3. Odontogenic tumours which develop from odontogenic ectomesenchyme with or without involvement of odontogenic epithelium.2 For such lesions “Odontoma” word was initially given by Paul Broca in 1866, who revealed the term as tumour occurred by the overgrowth of entire dental tissue. The growth of absolutely differentiated epithelial cells as functional ameloblast and mesenchymal cells as functional odontoblast can give rise to a different developmental anomaly coined as Odontomas.3 According to their behaviour and composition, odontomas can be considered as malformations or hamartomas rather than a true neoplasm. 4,5,6 In 2005, World Health Organization (WHO) classified two variants of odontomas, 1. Compound odontomas, which typically appears as unilocular lesions containing multiple radiopaque, tiny tooth like structures commonly known as denticles; and 2. Complex odontomas, which is comprised of an irregular mass of soft and hard dental tissues.

Meningiomas

2018 ◽  
Author(s):  
K. E. Hovinga ◽  
Y. Esquenazi ◽  
P. H. Gutin
Keyword(s):  
Treatment Strategies ◽  
Brain Structures ◽  
World Health ◽  
Spinal Tumors ◽  
Central Nervous System Tumors ◽  
Clinical Scenarios ◽  
The World ◽  
Specific Factors ◽  
Health Organization ◽  
Slow Growing

Meningiomas are the most common primary central nervous system tumors and account for about one third of all primary brain and spinal tumors. They are classified according to the World Health Organization into 3 groups (I–III). Treatment strategies range from observation, surgery, and/or a radiation therapy. Many meningiomas are slow growing and discovered incidentally. Symptoms can vary widely, depending on the location. Patient’s specific factors and the location of the meningioma in relation to critical brain structures are all important factors in determining the optimal treatment. This chapter presents common clinical scenarios of meningioma. Differential diagnosis, perioperative workup, surgical nuances, and postoperative complications are discussed.

Ameloblastic Fibroma: A Rare Entity of the Mandible

2019 ◽  
Vol 152 (Supplement_1) ◽  
pp. S48-S48
Author(s):  
Sakshi Sakshi ◽  
Riya Kuklani
Keyword(s):  
Cell Layer ◽  
World Health ◽  
Tissue Formation ◽  
Hard Tissue ◽  
Radiological Findings ◽  
Unerupted Tooth ◽  
Odontogenic Epithelium ◽  
Ameloblastic Fibroma ◽  
Ameloblastic Fibrosarcoma ◽  
Health Organization

Abstract Ameloblastic fibroma (AF) is an uncommon benign odontogenic true mixed tumor comprising neoplastic epithelial and mesenchymal tissues. It constitutes only approximately 2% of odontogenic tumors and is defined by the World Health Organization (WHO) as “neoplasm composed of proliferating odontogenic epithelium embedded in cellular ectomesenchymal tissue that resembles the dental papilla and epithelial strands and varying degrees of inductive changes and dental hard tissue formation.” The tumor is most common in the first and second decades of life with a slight male predilection. The most common site is the posterior mandible and 75% of the cases are associated with an unerupted tooth. Radiologically, it may present as a unilocular or multilocular lesion. The treatment of choice could range from aggressive curettage for a small unilocular lesion to wide local excision for a large multilocular lesion. The prognosis is usually good, with a recurrence rate of approximately 20%. Here we present a case of a 13-year-old male with a multilocular expansile cystic lesion associated with nonvital tooth 20 and tooth 21 since 2016. An incisional biopsy was performed and the microscopic examination revealed small masses of cellular fibrous and myxoid connective tissue containing long narrow cords of odontogenic epithelium. The odontogenic islands were basophilic with peripheral nuclear palisading of the basal cell layer, consistent with an ameloblastic fibroma. Complete curettage was performed and the patient is being followed up with no recurrence since 2 months. We reviewed the literature with regard to clinical, histopathological, and radiological findings and reached the conclusion that malignant transformation of ameloblastic fibroma into ameloblastic fibrosarcoma is uncommon but well documented. AF needs to be distinguished from ameloblastoma and ameloblastic fibrosarcoma, since these two tumors can be locally invasive and have greater potential for recurrence than ameloblastic fibroma.

scholarly journals Queratocisto odontogênico em mandíbula: relato de caso

2020 ◽  
Vol 9 (6) ◽  
pp. 665-669
Author(s):  
Thauany Vasconcelos ◽  
Lucas André Barros Ferreira ◽  
Sirius Dan Inaoka ◽  
Davi Felipe Neves Costa
Keyword(s):  
Rio De Janeiro ◽  
Benign Lesion ◽  
Odontogenic Tumor ◽  
World Health ◽  
Keratocystic Odontogenic Tumor ◽  
Imaging Features ◽  
Odontogenic Tumours ◽  
Health Organization ◽  
Head Neck

Introdução: O queratocisto odontogênico é por definição um cisto de desenvolvimento que apresenta caráter agressivo afetando o complexo bucomaxilofacial. Tendo em vista que muitas vezes são assintomáticos, o seu diagnóstico normalmente é obtido através de exames radiográficos de rotina. Objetivo: apresentar um caso clínico referente ao diagnóstico e tratamento de um queratocisto odontogênico em região posterior de mandíbula. Caso clínico: Paciente do sexo feminino, normosistemica, feoderma. Observou-se aumento de volume extraoral, lado direito da face em região de ângulo mandibular. Ao exame radiografico periapical, observou-se uma imagem radiolúcida, bem delimitada, unilocular, associada ao dente 47.  Ao exame físico intraoral, observou-se abaulamento ósseo na região do referido dente. Foi então solicitada uma tomografia computadorizada, na qual foi detectada extensa lesão óssea expansiva em ramo mandibular direito. Realizou-se uma punção aspirativa local, detectando presença de conteúdo líquido. Primeiramente foi realizada uma biópsia incisional com instalação de dispositivo descompressivo. O laudo histopatológico foi de cisto odontogênico inflamatório. O dispositivo de descompressão permaneceu por 9 meses, apresentando uma diminuição significativa da lesão. Foi realizada então, a enucleação da lesão remanescente, associado a exodontia dos dentes 47 e 48 e enviado material para histopatológico, que dessa vez, confirmou diagnóstico de queratocisto odontogênico. Ao exame de imagem pós-operatório de 6 meses, observou-se formação óssea completa sem sinais de recidiva. Conclusão: O tratamento proposto se mostrou eficaz no tratamento do queratocisto odontogênico, o acompanhamento com exames de imagem é de extrema importância, tendo em vista a possibilidade de recidiva. Descritores: Recidiva; Cistos Odontogênicos; Patologia Bucal. Referências Freitas DA, Veloso DA, Santos ALD, Freitas VA. Ceratocistoodontogênico maxilar: relato de caso clínico. RGO Rev Gauch Odontol. 2015;63(4):484-88. Antunes AA, Avelar RL, Santos TS, Andrade ESS, Dourado E. Tumor odontogênico ceratocístico: análise de 69 casos/ Keratocystic odontogenic tumor: analysisof 69 cases. Rev bras cir cabeça pescoço. 2007;36(2):80-2. Moura BS, Cavalcante MA, Hespanhol W. Tumor odontogênico ceratocístico. Rev Col Bras Cir. 2016;43(6):466-71. Wright JM, Vered M. Update from the 4th Edition of the World Health Organization Classification of Head and Neck Tumours: Odontogenic and Maxillofacial Bone Tumors. Head Neck Pathol. 2017;11(1):68-77. Neville BW, Allen CM, Damm DD, Chi A. oral and maxillofacial pathology, 4. ed. Rio de Janeiro: Elsevier; 2016. Aciole GTS, Santos MAM, Aciole JMS, Ribeiro Neto N, Pinheiro, ALB. Tumor odontogênicoqueratocistorecidivante: tratamento cirúrgico conservador ou radical? Relato de caso clínico. Rev cir traumatol buco-maxilo-fac. 2010;10(1):43-8. Hupp JR. Cirurgia oral e maxilofacial contemporânea. 6. ed. Rio de Janeiro: Elsevier, 2015. Marques JAF, Neves, JL, Alencar, DA, Lemos IM, Marques LC. Ceratocisto Odontogênico: relato de caso. Sitientibus. 2006;34(1):59-69. Conceição ACA, Santos AM, Santos GP, Almeida AJ, Dias AMN, Mainenti P. Tumor odontogênico queratocístico: atualidades. RIEE. 2012;4(1): 29-35. Pereira CCS, Carvalho ACG de S, Jardim ECG, Shinohara EH, Garcia Júnior IR. Tumor Odontogênico Queratocístico e considerações diagnósticas. RBCS. 2012;10(32):73-9. Balmick S, Hespanhol W, Cavalcante MAA, Gandelmann IHA. Recidiva do Tumor Odontogênico Ceratocístico: Análise retrospectiva de 10 anos. Rev cir traumatol buco-maxilo-fac. 2011;11(1):85-91. Borghesi A, Nardi C, Giannitto C, Tironi A, Maroldi R, Di Bartolomeo F, Preda L. Odontogenic keratocyst: imaging features of a benign lesion with an aggressive behaviour. Insights Imaging. 2018;9(5):883-97.  Johnson NR, Batstone MD, Savage NW. Management and recurrence of keratocystic odontogenic tumor: a systematic review. Oral Surg Oral Med Oral Pathol Oral Radiol. 2013;116(4):e271-76. Araújo S, Oliveira LKR, Pigatti FM, Mayrink G. Queratocisto odontogênico em região anterior da maxila: relato de caso. HU rev. 2019;45(1):82-6. Oliveira Júnior HCC, Chaves Netto HDM, Rodrigues MTV, Pinto JMV, Nóia CF. Descompressão cirúrgica no tratamento de lesões císticas da cavidade oral. Rev cir traumatol buco-maxilo-fac. 2014;14(1):15-20. Pazdera J, Kolar Z, Zboril V, Tvrdy P, Pink R. Odontogenic keratocysts/keratocystic odontogenic tumours: biological characteristics, clinical manifestation and treatment. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub. 2014;158(2):170-74.

scholarly journals A rare case of an intramedullary metastasis of a myxopapillary ependymoma

2019 ◽  
Vol 10 ◽  
pp. 83 ◽  
Author(s):  
Lino Fonseca ◽  
Marta Cicuendez ◽  
Francisco Martínez-Ricarte ◽  
Elena Martínez-Saez ◽  
Esteban Cordero ◽  
...  
Keyword(s):  
Cauda Equina ◽  
World Health ◽  
Subtotal Resection ◽  
Myxopapillary Ependymoma ◽  
World Health Organization Classification ◽  
History Of ◽  
Intradural Metastasis ◽  
Health Organization ◽  
Slow Growing

Background: Myxopapillary ependimoma (MPE) is a benign slow-growing tumor, and it has been designated histologically as a Grade I neoplasm according to the 2016 World Health Organization classification. Despite the benign character, dissemination and metastasis have occasionally been reported. The retrograde dissemination to other levels of the neuraxis is extremely rare, being more frequent to the intracranial compartment. Case Description: We hereby present a case of medullary metastasis of cauda equina MPE, with a history of having undergone a subtotal resection and postoperative adjuvant radiotherapy. The patient presents complaints of night dorsal pain attributable to intradural metastasis twenty-one years after the first surgical intervention. Conclusion: The case reported highlights the importance of long follow-up in patients with MPE, since the possibility of secondary seeding to distant craniospinal sites or local spinal sites after surgery, and radiotherapy should be considered in metastatic disease.

scholarly journals A path less travelled — Short review on ossifying fibroma and osseous dysplasia

2021 ◽  
Vol 11 (2) ◽  
pp. 90-95
Author(s):  
Deepali P Mohite ◽  
Devendra H Palve ◽  
Snehal R Udapure ◽  
Vinanti V Bodele ◽  
Mrunali D Jambhulkar ◽  
...  
Keyword(s):  
Fibrous Tissue ◽  
Short Review ◽  
World Health ◽  
Ossifying Fibroma ◽  
Osseous Lesion ◽  
Osseous Dysplasia ◽  
Cementifying Fibroma ◽  
Calcified Tissue ◽  
Health Organization ◽  
Slow Growing

Fibro-osseous lesions (FOL) are characterized by replacement of normal bone by fibrous tissue containing a newly formed mineralized product. The mineralized product may be ossification (sometimes cementum formation) or calcification of fibrous tissue by metaplasia. These lesions have similar radiographic and histopathologic features hence the term fibre- osseous lesion is not a diagnosis, rather a description of the presence of fibrous and calcified tissue. They may be developmental (fibrous dysplasia), reactive (cemento-osseous dysplasia) or neoplastic (ossifying/cementifying fibroma). This article presents the commonly used classification for fibro-osseous lesions and an insight into a few changes that have been introduced in the recent past with emphasis on Ossifying Fibroma and Osseous Dysplasia.Ossifying fibromas are considered as benign fibro-osseous neoplasms which are principally encountered within the jawbones. Cemento-osseous dysplasias are non-neoplastic fibro- osseous lesion. Since 1971, the World Health Organization classified cemental lesions into 4 distinct entities, as follows: Periapical Cemental Dysplasia, Benign Cementoblastoma (true cementoma), Cementifying Fibroma and Gigantiform Cementoma (GC). The term, gigantiform cementoma, may imply a solitary process but it is misleading because the condition typically presents as slow-growing, multifocal/multiquadrant and expansile lesions involving both jaws. WHO classified it in Osseous dysplasia and El-Mofty et al. under Ossifying fibroma.

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