Three-Dimensional Ultrasonographic Reslicing of the Fetal Brain to Assist Prenatal Diagnosis of Central Nervous System Anomalies

2006 ◽  
Vol 25 (4) ◽  
pp. 509-514 ◽  
Author(s):  
Karim D. Kalache ◽  
Katja Eder ◽  
Tilman Esser ◽  
Hans Proquitté ◽  
Gisela Stoltenburg-Didinger ◽  
...  
2010 ◽  
Vol 24 (3) ◽  
pp. 502-505 ◽  
Author(s):  
Zehra Sema Özkan ◽  
Hasan Çilgin ◽  
Hatice Banu Aygün ◽  
Derya Devecı ◽  
Mehmet Şımşek ◽  
...  

2010 ◽  
Vol 36 (S1) ◽  
pp. 267-267
Author(s):  
J. Bello-Muñoz ◽  
P. Oliveros ◽  
T. Higueras Sanz ◽  
I. Boada ◽  
E. Carreras Moratonas ◽  
...  

Author(s):  
Elsa Viora ◽  
Giulia Polarolo ◽  
Simona Bastonero ◽  
Elena Gullino ◽  
Silvia Stillavato ◽  
...  

ABSTRACT Prenatal diagnosis of central nervous system (CNS) congenital anomalies is possible in the second and third trimester. Earlier diagnosis is possible for some of these as the complex acranial/exencephaly/anencephaly and alobar holoprosencephaly (HPE). The knowledge of normal fetal brain development and its ultrasound images at the different weeks’ gestation, the expertise of operators, and high-resolution equipment are essential to obtain good results. The diagnosis in the first trimester of some major anomalies incompatible with extrauterine life or associated with severe handicap is useful to inform the couple, to perform additional examinations, and provide them with the option of earlier and safer pregnancy termination. For some other conditions, like agenesis of corpus callosum and hypoplasia or absence of cerebellar vermis, the diagnosis is possible only in the second trimester, so beware not to falsely reassure or scare expecting parents. In conclusion, first trimester ultrasound could be useful for early detection of some CNS anomalies, but caution could be used for others, particularly in counseling couples about prognostic significant of ultrasound findings. How to cite this article Viora E, Polarolo G, Bastonero S, Gullino E, Stillavato S, Sciarrone A. Central Nervous System Anomalies Detectable in the First Trimester. Donald School J Ultrasound Obstet Gynecol 2017;11(4):261-267.


1995 ◽  
Vol 7 (1) ◽  
pp. 47-60 ◽  
Author(s):  
Ruth B Goldstein

Among serious fetal anomalies currently detectable with ultrasound, defects of the central nervous system (CNS) are among the most common. These congenital anomalies are especially likely to burden not only affected children with severely limiting handicaps, but also their families with long-lasting anguish and financial responsibility. It is appropriate that interest in methods for improving prenatal detection of these abnormalities has intensified. Alphafetoprotein screening programmes are now widely available, and many papers have been written describing useful sonographic observations that enhance prenatal diagnosis. As a consequence, the majority of the most common serious neural axis defects including fetal hydrocephalus, anencephaly, myelomeningocele and encephalocele, previously detected almost exclusively at birth, today can be accurately detected prenatally. A few observations in the fetal brain and spine have proven to be especially useful in this task. This article presents a simplified and effective approach to the general sonographic survey of the neural axis in fetuses at average and increased risk for these anomalies. The aim is to improve not only accuracy of diagnosis of CNS malformations, but the efficiency and confidence of the examiner.


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