Likelihood Ratio-Based Differentiation of Nodular Hashimoto Thyroiditis and Papillary Thyroid Carcinoma in Patients With Sonographically Evident Diffuse Hashimoto Thyroiditis

2012 ◽  
Vol 31 (11) ◽  
pp. 1767-1775 ◽  
Author(s):  
Liang Wang ◽  
Yu Xia ◽  
Yu-Xin Jiang ◽  
Qing Dai ◽  
Xiao-Yi Li
Medicine ◽  
2015 ◽  
Vol 94 (44) ◽  
pp. e1881 ◽  
Author(s):  
Ye-Feng Cai ◽  
Qing-Xuan Wang ◽  
Chun-Jue Ni ◽  
Gui-Long Guo ◽  
Quan Li ◽  
...  

Author(s):  
Rogério Aparecido Dedivitis ◽  
Leandro Luongo de Matos ◽  
Felipe Guilherme Silva Souza ◽  
Jose Luis Bogado Ortiz

Abstract Introduction Hashimoto thyroiditis (HT) shares many characteristics with papillary thyroid carcinoma (PTC), and some studies show that, when associated, PTC is diagnosed mostly with smaller lesions and multifocal pattern. Objective To evaluate the relationship between HT and PTC. Methods A retrospective study of 155 patients who underwent total thyroidectomy from 2009 to 2015. Demographical, clinical and ultrasonographical data, as well as anatomopathological findings were evaluated. Results There were signs of thyroidits in 35 patients, and 114 patients had a unifocal disease. There was no statistical significance between the variables studied and thyroiditis. However, when compared with the occurrence of unifocal or multifocal lesions, there was statistical significance regarding age (p = 0.038) and mass (p = 0.031). There was no direct relationship between thyroiditis and multifocality (p = 0.325) nor between thyroiditis and cervical extension of the disease (p = 0.300 e p = 0.434). Conclusion There was no relationship between thyroiditis and multifocality in cases of PTC.


2014 ◽  
Vol 20 (3) ◽  
pp. 463-473 ◽  
Author(s):  
Hee Yong Kwak ◽  
Byung Joo Chae ◽  
Yong Hwa Eom ◽  
Young Ran Hong ◽  
Jae Beom Seo ◽  
...  

PLoS ONE ◽  
2021 ◽  
Vol 16 (5) ◽  
pp. e0251676
Author(s):  
Yan liu ◽  
Houfa Geng ◽  
Xuekui Liu ◽  
Mingfeng Cao ◽  
Xinhuan Zhang

Background Aim of this meta-analysis was to evaluate the overall diagnostic value of circulating mini miRNAs for papillary thyroid carcinoma (PTC) and to find the possible molecular marker with higher diagnostic value for PTC. Methods We searched the Pubmed, Cochrane and Embase database until June 2020. We selected relevant literatures associated with the diagnosis of PTC with circulating miRNAs. The number of cases in experimental group and the control group, sensitivity and specificity could be extracted from the literatures. Results We got 9 literatures including 2114 cases of PTC. Comprehensive sensitivity was 0.79, comprehensive specificity was 0.82, positive likelihood ratio was 4.3, negative likelihood ratio was 0.26, diagnostic advantage ratio was 16. The summary receiver operating characteristic curve was drawn and the Area Under the Curve was 0.87. Conclusions Circulating microRNAs may be promising molecular markers for the diagnosis of papillary thyroid carcinoma. Combined detection of certain serum microRNAs can improve the diagnostic accuracy of papillary thyroid carcinoma. Especially MiR-222 and miR-146b may be prime candidates for the diagnosis of PTC in Asian population.


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