scholarly journals A RANDOMIZED COMPARATIVE CLINICAL TRIAL OF SWARNMAKSHIKA BHASMA AND COMPOUND (SWARNMAKSHIKA BHASMA AND YASHADA BHASMA) IN THE MANAGEMENT OF PANDU WITH SPECIAL REFERENCE TO IRON DEFICIENCY ANEMIA

2015 ◽  
Vol 6 (2) ◽  
pp. 250-255
Author(s):  
Meghna Vaidya ◽  
Abhishek Upadhyay
Keyword(s):  
Clinical Trial ◽  
Iron Deficiency ◽  
Special Reference ◽  
Iron Deficiency Anemia ◽  
Deficiency Anemia ◽  
Comparative Clinical Trial

AN AMELIORATE COMPARATIVE CLINICAL TRIAL OF NAVAYAS LOUHA SYRUP AND NISHA LOUHA SYRUP IN THE MANAGEMENT OF PANDU ROGA WITH SPECIAL REFERENCE TO IRON DEFICIENCY ANEMIA IN CHILDREN

2021 ◽  
Vol 12 (4) ◽  
pp. 56-61
Author(s):  
Bharti Tiwari ◽  
Amar Singh Tiwari ◽  
Satish Chand Gupta
Keyword(s):  
Clinical Trial ◽  
Iron Deficiency ◽  
Special Reference ◽  
Iron Deficiency Anemia ◽  
Clinical Efficacy ◽  
Health Problem ◽  
Deficiency Anemia ◽  
Indian Children ◽  
Major Health Problem ◽  
Comparative Clinical Trial

Anemia is a major health problem in India. Yet, a comprehensive plan of action to combat this public health problem has been still missing. There are few existing plans for the control of Iron Deficiency Anemia regarding children and pregnant women and lactating mothers. Iron deficiency is the result of long-term negative iron balance. Iron deficiency anemia (IDA) should be regarded as a subset of iron deficiency, that is, it represents the extreme lower end of the distribution of iron deficiency. Treatment options include oral and intravenous iron therapy; however, the efficacy of oral iron is limited in certain gastrointestinal conditions, such as inflammatory bowel disease, celiac disease, and autoimmune gastritis. So that ameliorate comparative clinical trial was taken with Ayurveda formulation for the diagnosis and treatment of iron deficiency anemia (IDA) with special reference to Pandu Roga. Overall, in the study Navayas Louha was found to have 76.53% and of Nisha Louha was found to have 69.33% clinical efficacy. The study showed that trial clinical efficacy of Navayas Louha syrup is better than Nisha Louha syrup in the management of iron deficiency anemia in Indian children.

scholarly journals Efficacy of SXN in the Treatment of Iron Deficiency Anemia: A Phase IV Clinical Trial

2019 ◽  
Vol 2019 ◽  
pp. 1-9
Author(s):  
Lu Ding ◽  
Lulin Xu ◽  
Yanxia Jin ◽  
Yongchang Wei ◽  
Yunbao Pan ◽  
...  
Keyword(s):  
Clinical Trial ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Status ◽  
Deficiency Anemia ◽  
High Dose ◽  
Mean Corpuscular Hemoglobin ◽  
Corpuscular Hemoglobin ◽  
Adults And Children ◽  
Phase Iv

Shengxuening (SXN) tablet is extracted from the excrement of the silkworm and has effects on hematopoiesis. The main components of SXN are chlorophyll derivatives and sodium iron chlorophyllin (SIC). The present study aims to investigate the efficiency and safety of SXN on iron deficiency anemia. This phase IV, multicenter, open-label, randomized clinical trial was conducted in 31 hospitals in China from June 2001 to April 2002. Adults and children were randomly divided into low-dose (L-SXN), medium-dose (M-SXN), and high-dose (H-SXN) groups, respectively. The course of treatment was 1 month. Peripheral hemogram levels and iron status were examined before and after treatment. Adults in all three dose groups demonstrated a significant increase in hemoglobin (HGB) concentration. Children who received SXN treatment in medium and high doses also demonstrated increased HGB concentration. Reticulocyte counts increased at the end of treatment in the M-SXN and H-SXN adult groups and in the M-SXN child group. For both children and adults, SXN in the three dose groups was found to significantly elevate red blood cell level, mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration. The total effective rate in the SXN-treated group reached 84.8%. The incidence of adverse events was 4.07%. The most common side effects were nausea (2.83%), diarrhea (0.74%), and rash (0.25%). SXN was proved to be efficient and safe for adults and children with iron deficiency anemia.

scholarly journals A COMPARATIVE CLINICAL STUDY TO ASSESS THE EFFICACY OF KARIMBIRUMBADI KASHAYAM AND VASAGULUCHYADI KASHAYAM IN PANDUROGA WITH SPECIAL REFERENCE TO IRON DEFICIENCY ANEMIA IN THE REPRODUCTIVE AGE GROUP OF WOMEN

2020 ◽  
pp. 13-18
Author(s):  
Muhammed Nizamudheen C H ◽  
Soumya S B
Keyword(s):  
Iron Deficiency ◽  
Special Reference ◽  
Iron Deficiency Anemia ◽  
T Test ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Age Group ◽  
Group A ◽  
Group B ◽  
Reproductive Age Group

This study is an attempt to clinically analyze the independent effect of Karimbirumbadi kashayam and Vasaguluchiadi kashayam in Panduroga and also compare their efficacy. Aims and Objectives: To evaluate the comparative efficacy of Karimbirumbadi kashayam and Vasaguluchyadi kashayam in Panduroga with special reference to iron deficiency anemia in the reproductive age group of women. Methodology: Among 46 registered subjects, 22 were registered in group A and 24were registered in group B. Out of which 20 subjects of A group and 20 subjects of B group completed the study. Group A was administered with 25ml of Karimbirumbadi kashayam with 40ml of luke warm water twice daily before food for 2 months and Group B was administered with 25ml of Vasaguluchyadi kashayam with 40ml of luke warm water and 10ml of Madhu as Anupana twice daily before food for 2 months. Objective and subjective parameters were analyzed using paired T test and Wilcoxon signed rank test respectively. Independent T test and Mann-Whitney U test were used to compare the parameters between the groups. Result: There was statistically significant improvement in the objective and subjective parameters (p<0.05 was observed). Conclusion: The study shows that both Karimbirumbadi kashayam and Vasaguluchyadi kashayam are effective in relieving the symptoms of Panduroga. Symptomatic relief was seen in both the group A & B, but there was no statistically significant difference between the groups in relieving these symptoms.

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