scholarly journals A COMPARATIVE CLINICAL STUDY TO ASSESS THE EFFICACY OF KARIMBIRUMBADI KASHAYAM AND VASAGULUCHYADI KASHAYAM IN PANDUROGA WITH SPECIAL REFERENCE TO IRON DEFICIENCY ANEMIA IN THE REPRODUCTIVE AGE GROUP OF WOMEN

2020 ◽  
pp. 13-18
Author(s):  
Muhammed Nizamudheen C H ◽  
Soumya S B
Keyword(s):  
Iron Deficiency ◽  
Special Reference ◽  
Iron Deficiency Anemia ◽  
T Test ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Age Group ◽  
Group A ◽  
Group B ◽  
Reproductive Age Group

This study is an attempt to clinically analyze the independent effect of Karimbirumbadi kashayam and Vasaguluchiadi kashayam in Panduroga and also compare their efficacy. Aims and Objectives: To evaluate the comparative efficacy of Karimbirumbadi kashayam and Vasaguluchyadi kashayam in Panduroga with special reference to iron deficiency anemia in the reproductive age group of women. Methodology: Among 46 registered subjects, 22 were registered in group A and 24were registered in group B. Out of which 20 subjects of A group and 20 subjects of B group completed the study. Group A was administered with 25ml of Karimbirumbadi kashayam with 40ml of luke warm water twice daily before food for 2 months and Group B was administered with 25ml of Vasaguluchyadi kashayam with 40ml of luke warm water and 10ml of Madhu as Anupana twice daily before food for 2 months. Objective and subjective parameters were analyzed using paired T test and Wilcoxon signed rank test respectively. Independent T test and Mann-Whitney U test were used to compare the parameters between the groups. Result: There was statistically significant improvement in the objective and subjective parameters (p<0.05 was observed). Conclusion: The study shows that both Karimbirumbadi kashayam and Vasaguluchyadi kashayam are effective in relieving the symptoms of Panduroga. Symptomatic relief was seen in both the group A & B, but there was no statistically significant difference between the groups in relieving these symptoms.

scholarly journals IRON DEFICIENCY ANEMIA

2010 ◽  
Vol 17 (04) ◽  
pp. 686-690
Author(s):  
SHEZADI SABAH ◽  
MUSARAT RAMZAN ◽  
IRUM FATIMA
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Reproductive Age ◽  
Plant Protein ◽  
Deficiency Anemia ◽  
P Value ◽  
Age Group ◽  
Balanced Diet ◽  
Nutritional Score ◽  
Reproductive Age Group

To determine the frequency of different causes of iron deficiency anemia in female patients of reproductive age group. 2) To determine the association between lack of balanced diet and iron deficiency anemia. Design: cross-sectional analytical study. Setting: Federal government services hospital, Islamabad. Period: From July 2008 to November 2008. Material and Methods: The study included female patients of reproductive age group i.e. 15-49 years of age having hemoglobin less than 11.5g/dl. The sampling technique was purposive. The data was analyzed using Microsoft excel 2000 and SPSS 10.0. Pearson correlation coefficient was used to determine the direction of relationship between total nutritional score and level of hemoglobin; student’s t-test was used to determine the significance of association. A pvalue of less than 0.05 was considered significant. Results: A positive correlation was observed between total nutritional score and level of hemoglobin (r = 0.402, p-value = 0.008). Correlation between animal protein and level of hemoglobin was 0.438 (p-value = 0.004) while between plant protein and level of hemoglobin was 0.211 (p-value = 0.179). Conclusions: It is concluded that there is a definite role of nutritional deprivation in the development of iron deficiency anemia. Lack of balanced diet especially protein group has much stronger association with thistype of anemia. Animal protein as compared to plant protein has strong association with the development of iron deficiency anemia. 

scholarly journals A Study to Assess the Knowledge on Iron Deficiency Anemia among Reproductive Age Group (20-45 Year) Women in Selected Rural Area of Lucknow

2021 ◽  
Vol 01 (01) ◽  
pp. 24-28
Author(s):  
Laxmi Shukla ◽  
◽  
Dimpal Singh ◽  
Ranjeet Kumar ◽  
Sabiya Khatoon ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Public Health Problem ◽  
Reproductive Age ◽  
Deficiency Anemia ◽  
Major Public Health Problem ◽  
Age Group ◽  
Mortality And Morbidity ◽  
Level Of Knowledge ◽  
Reproductive Age Group

Background of the study: Anemia continues to be a major public health problem in developing countries including India. It is the most common cause of malnutrition in the world and is the eighth leading cause of diseases in girls and women in developing counties. About one third of the global population is anemic (WHO 2010) [1]. Knowledge regarding the causes, prevention and management of iron deficiency among reproductive age women plays an important role in reducing the mortality and morbidity rates. The aim of this study is to assess the knowledge regarding iron deficiency anemia among reproductive age group women. Methodology: By using descriptive survey design, 50 women who met the criteria were selected by purposive sampling technique. Structured questionnaire was used to gather the data Data were analyzed by descriptive and inferential statistics. Results: Findings shows that 6% of reproductive age group women had inadequate level of knowledge regarding anemia, 72% had moderate level of knowledge and 22% of them had adequate level of knowledge. Conclusion: Overall findings of this study revealed that knowledge on iron deficiency anemia was inadequate among reproductive age group women. There is a need to improve the health care services, facilities and more importantly knowledge among the women on topics related to anemia and its prevention.

scholarly journals Expression of Duodenal Iron Transporter Proteins in Diabetic Patients with and without Iron Deficiency Anemia

2018 ◽  
Vol 2018 ◽  
pp. 1-4 ◽  
Author(s):  
Efrat Broide ◽  
Ram Reifen ◽  
Shay Matalon ◽  
Zipi Berkovich ◽  
Haim Shirin
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Iron Transport ◽  
Deficiency Anemia ◽  
Diabetic Patients ◽  
Divalent Metal Transporter 1 ◽  
Divalent Metal Transporter ◽  
Transporter Proteins ◽  
Group A ◽  
Group B

The role of iron transport proteins in the pathogenesis of anemia in patients with diabetes mellitus (T2DM) is still unclear. We investigated the expression of duodenal transporter proteins in diabetic patients with and without iron deficiency anemia (IDA). Methods. Overall, 39 patients were included: 16 with T2DM and IDA (group A), 11 with T2DM without IDA (group B), and 12 controls (group C). Duodenal mucosal expression of divalent metal transporter 1 (DMT1), ferroportin 1 (FPN), hephaestin (HEPH), and transferrin receptor 1 (TfR) was evaluated by Western blotting. Chronic disease activity markers were measured as well. Results. FPN expression was increased in group A compared to group B and controls: 1.17 (0.72–1.46), 0.76 (0.53–1.04), and 0.71 (0.64–0.86), respectively (p=0.011). TfR levels were over expressed in groups A and B compared to controls: 0.39 (0.26–0.61), 0.36 (0.24–0.43), and 0.18 (0.16–0.24), respectively, (p=0.004). The three groups did not differ significantly with regard to cellular HEPH and DMT1 expression. The normal CRP and serum ferritin levels, accompanied with normal FPN among diabetic patients without IDA, do not support the association of IDA with chronic inflammatory state. Conclusion. In patients with T2DM and IDA, duodenal iron transport protein expression might be dependent on body iron stores rather than by chronic inflammation or diabetes per se.

scholarly journals CLINICAL EVALUATION OF PATIENTS SUFFERING FROM RHEUMATOID ARTHRITIS WITH RESPECT TO IRON DEFICIENCY

2019 ◽  
Vol 3 (7) ◽  
Author(s):  
Dr. Manish Kumar
Keyword(s):  
Rheumatoid Arthritis ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
General Medicine ◽  
Well Being ◽  
Deficiency Anemia ◽  
Therapy Goals ◽  
Group A ◽  
Keywords Rheumatoid Arthritis ◽  
Group B

Iron deficiency results in the decreased synthesis of important molecules including iron containing enzymes thereby inducing cellular organic functional disturbances. If not corrected in a timely manner, iron deficiency anemia (IDA) will ensue. The consequences of iron deficiency anemia (IDA) range from impaired psychological and physical well-being and decreased occupational abilities to developmental troubles in children and increased morbidity and mortality in some patient populations. Moreover, iron deficiency is a risk factor in various medical settings because it impedes erythropoietic response to acute and chronic anemia. Hence based on above findings the present study was planned to evaluate the levels of iron in rheumatoid The present study was planned in Department of General Medicine, All India Institute of Medical Sciences, Patna from jan 2018 to june 2018. Group A consist of 30 informed male and female consented patients diagnosed with Rheumatoid arthritis were enrolled for the study. The group B consist of 30 control patients for comparative evaluation. Hence from present study it can be concluded that, there is no known prevention for iron deficiency anaemia in rheumatoid arthritis (RA) patients other than the reduction of contributory factors. Therapy goals are to reduce pain and inflammation and improve quality of life. Surgery to repair, replace or fuse joints may help in serious conditions. Keywords: Rheumatoid Arthritis, Iron Deficiency, Heamoglobon, Iron, etc.

scholarly journals To evaluate the efficacy and safety of intravenous bolus versus intravenous infusion of iron sucrose in pregnant women with severe iron deficiency anemia

2017 ◽  
Vol 6 (6) ◽  
pp. 2417
Author(s):  
Urvashi Verma ◽  
Saroj Singh ◽  
Shikha Singh ◽  
Anu Pathak ◽  
Poonam Yadav ◽  
...  
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Gestational Age ◽  
Intravenous Infusion ◽  
Iron Sucrose ◽  
Deficiency Anemia ◽  
Intravenous Bolus ◽  
Medical College ◽  
Group A ◽  
Group B

Background: Objective of present study was to evaluate the efficacy and safety of intravenous bolus iron sucrose for iron deficiency anemia during pregnancy during second and third trimester women presenting at S.N. medical college, Agra.Methods: It was a prospective controlled trial and study was carried out in Department of Obstetrics and Gynecology, S.N. medical college, Agra in the year 2014-2016. 100Pregnant women with proved iron deficiency anemia having hemoglobin between 4-9gm/dl was included in this study. Total Iron deficit was calculated by standard formula. Target haemoglobin was 11gm/dl. Iron sucrose was administered by intravenous bolus and intravenous infusion techniques. Hemoglobin was repeated at 2 weeks, 4 weeks and 8 weeks after the last dose of intravenous iron sucroseResults: In Group A (bolus group n=50) 22 women had gestational age >24-28weeks and 20 women gestational age >18-24 weeks, with Mean gestational age of 24.36±3.78 weeks. In Group B (infusion group n=50) most of the patients 24 (48%) had gestational age >24-28 weeks, 18 (36%) had gestational age >18-24 weeks, with Mean gestational age of 24.94±3.51 weeks. Target hemoglobin was achieved in group A in all 50 (100%) cases and in group B in 49 (98%) cases. There were no allergic reactions.Conclusions: This study showed a significant improvement in the hemoglobin of the patients after receiving intravenous bolus and intravenous infusion of iron sucrose. Patients achieved the target hemoglobin of 11gm/dl. Both therapies are safe, effective and faster acting for the treatment of iron deficiency anaemia during pregnancy. The bolus push technique is more convenient to women and care provider, less time consuming as well as cost effective.

scholarly journals A Comparative Study to Evaluate the Efficacy and Safety of Single Dose Intravenous Iron Carboxymaltose vs Multidose Iron Sucrose in Postpartum Cases of Severe Iron Deficiency Anemia

2015 ◽  
Vol 7 (1) ◽  
pp. 18-21
Author(s):  
Ruchika Garg ◽  
Renu Rajvanshi
Keyword(s):  
Adverse Reaction ◽  
Single Dose ◽  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Intravenous Iron ◽  
Iron Sucrose ◽  
Deficiency Anemia ◽  
Efficacy And Safety ◽  
Group A ◽  
Group B

ABSTRACT Objective To evaluate the efficacy and safety of single dose intravenous iron carboxymaltose vs multidose iron sucrose in postpartum cases of severe iron deficiency anemia. Materials and methods One hundred cases with iron deficiency anemia in postpartum patient were selected from postpartum wards and assigned in two groups of 50 each. In group A, iron carboxymaltose injection administered by intravenous infusion upto a maximum single dose of 20 ml of iron carboxymaltose injection (1000 mg of iron). In group B Iron sucrose was given as 200 mg elemental iron (2 ampules of 5 ml) in 100 ml of 0.9% normal saline infusion over 15 minute alternate days up to 5 days. All the patients were monitored for rise in hemoglobin level at 2, 4, 8 and 12 weeks of iron therapy, adverse effect and rise in hematological parameter at 4 weeks. Results In group A, mean Hb level rise is 3.95 g/dl and in group B, it is 3.32 g/dl at 4 weeks of initial therapy. In group A, 100% cases achieved target Hb at 12 weeks after therapy while in group B 98% cases achieved target Hb at 12 weeks after therapy. In group A, 12% cases have grade 1 adverse reaction while in group B, 20% cases have adverse reaction. Conclusion Administration of intravenous iron has a good clinical result, with minimum adverse reactions. Thus, we can conclude that intravenous iron carboxymaltose therapy is safe, convenient, more effective and faster acting than intravenous iron sucrose for treatment of severe iron deficiency anemia in postpartum patient. How to cite this article Garg R, Singh S, Singh S, Rajvanshi R. A Comparative Study to Evaluate the Efficacy and Safety of Single Dose Intravenous Iron Carboxymaltose vs Multidose Iron Sucrose in Postpartum Cases of Severe Iron Deficiency Anemia. J South Asian Feder Obst Gynae 2015;7(1):18-21.

scholarly journals IRON DEFICIENCY ANEMIA

2018 ◽  
Vol 25 (04) ◽  
pp. 492-496
Author(s):  
Jawaria Khalid ◽  
Muhammed Mehboob Ahmed ◽  
Misbah Khalid ◽  
Muhammad Asghar Butt ◽  
Khalid Mahmood Akhtar
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Ferrous Sulfate ◽  
Ferrous Sulphate ◽  
Acute Infection ◽  
Randomized Study ◽  
Deficiency Anemia ◽  
Treatment Groups ◽  
Group A ◽  
Group B

Objective: To compare the efficacy of Ferrous sulfate with iron polymaltosecomplex in treatment of iron deficiency anemia in children in terms of rise in hemoglobin. Studydesign: Randomized clinical trial. Setting: Department of Paediatric Medicine Unit I AlliedHospital Faisalabad. Study duration: 6 months. Methodology: All the children of age group6 month to 12year with hemoglobin level <10g/dl, MCV<70fl corrected for age, MCHC<32%,serum ferritin<8μg/l were included. All other cases of anemia other than iron deficiency anemiasuch as thalassemia, sickle cell anemia, lead poisoning etc, patients with severe anemia(hb≤6g/dl) because they need blood transfusion to correct anemia, those with decompensatedheart failure or acute infection were excluded. After enrolment patients were randomly dividedinto two groups by lottery method. Group A, patients were given ferrous sulphate. Group B,patients were given iron polymaltose complex (IPC). Both iron preparations were given inthe dose of 5mg/kg/day of elemental iron in three divided dosage 30 minutes before meals.Patients were assessed at one month interval after the start of treatment and hemoglobin waschecked at follow up visit by taking 2cc blood. Results: Sixty children were studied. Meanage was 2.5 ± 5.1 years, range 7 months to 12 years with 32 girls, 28 boys. The patients wereevenly distributed between the two treatment groups (IPC, n = 30, 50%; ferrous sulfate, n =30, 50%). All erythrocyte-related hematologic parameters after one month treatment showed asignificant improvement from baseline with both treatments. A significant improvement in Hbwas observed after one month treatment in the IPC group 9.5 ± 1.1g/dL to 10.6 ±1.0 g/dL andthe ferrous sulfate group 9.4 ± 1.6 g/dL to 11.2 ± 0.9 g/dL which was statistically significant.Conclusion: From this randomized study, it is concluded that both ferrous sulphate and ironpolymaltose complex have equal efficacy in treatment of iron deficiency anemia

scholarly journals Comparison of ferric carboxymaltose versus Iron Sucrose for treatment of iron deficiency anemia in pregnancy.

2021 ◽  
Vol 28 (04) ◽  
pp. 481-484
Author(s):  
Hira Jamal ◽  
Humaira Zafar ◽  
Mubashra Naz ◽  
Umber Fatima ◽  
Anees Fatima
Keyword(s):  
Iron Deficiency ◽  
Iron Deficiency Anemia ◽  
Intravenous Iron ◽  
Iron Sucrose ◽  
Deficiency Anemia ◽  
Ferric Carboxymaltose ◽  
P Value ◽  
Iron Treatment ◽  
Group A ◽  
Group B

Objective: To compare the mean increase in hemoglobin level with ferric carboxymaltose injection and iron sucrose injection for the management of the pregnant females presenting with iron deficiency anemia. Study Design: Randomized Controlled Trial. Settings: Department of Obstetrics and Gynecology Madina Teaching Hospital affiliated with University medical and Dental College Faisalabad. Period: July 2019 to December 2019. Material & Method: A total number of 100 patients presented in OPD satisfying the selection criteria were enrolled in the study after permission from ethical committee. On enrollment, a detailed clinical history which include previous iron treatment including and chronic medical disorders was taken. Clinical examination was done. Investigations for anemia include hemoglobin, reticulocyte count, peripheral film and red cell indices, serum ferritin level and Hb electrophoresis if indicated. The patients were randomly divided in two groups. In group A, females were given ferric carboxymaltose and in group B, females were given iron sucrose. After calculating the total iron deficit, patients in group A were given intravenous FCM. Patients in group B were given IS. Follow up of the patient was done after 3 weeks of intravenous iron treatment. The baseline Hb and values after 3 weeks of intravenous iron treatment were compared between the FCM and IS groups and increase in Hb level calculated as mean and SD. Both groups were analyzed for rise in Hb level by using independent sample t test. P value < 0.05 was taken as significant. Results: A total 100 pregnant female were found eligible for study, and were randomized into two groups of 50 each. Mean increase in hemoglobin level with ferric carboxymaltose and iron sucrose was evaluated, it shows that baseline Hb was 8.84±0.68 in Group A and 8.78 ±0.76 in Group B, P value was 0.67, after treatment Hb was 12.02±0.89 in Group A and 10.92 ±0.99 in Group B. Mean increase was 3.18 ±0.60 in Group A and 2.14±0.81 in Group B. P value was 0.001. Conclusion: Ferric carboxymaltose significantly increase Hb level and restores the iron stores as compare to iron sucreose. FCM is safe and effective intravenous treatment for iron deficiency anemia in pregnancy. FCM has the advantages of single large dose administration and fewer hospital visit. FCM is most suitable drug for the treatment of patients with IDA who required quick replenishment of iron stores.

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