Determination of Optimum Processing Conditions for the Proximate Composition and Pasting Characteristics of Flour Made from Parboiled Cassava Chips: A Response Surface Analysis

2018 ◽  
Vol 6 (1) ◽  
pp. 1-13
Author(s):  
M. Ogbonnaya ◽  
M. O. Iwe
Keyword(s):  
Response Surface ◽  
Surface Analysis ◽  
Proximate Composition ◽  
Response Surface Analysis ◽  
Processing Conditions ◽  
Optimum Processing ◽  
Pasting Characteristics

Urinary alanine aminopeptidase assay improved as result of multivariate response-surface analysis.

1988 ◽  
Vol 34 (5) ◽  
pp. 954-957 ◽  
Author(s):  
C Flandrois ◽  
C Lahet ◽  
D Feldmann ◽  
J M Gabastou ◽  
A Gonnon ◽  
...  
Keyword(s):  
Response Surface ◽  
Surface Analysis ◽  
Response Surface Analysis ◽  
Tris Buffer ◽  
Multivariate Response ◽  
Multivariate Study ◽  
Alanine Aminopeptidase

Abstract Optimization of determination of alanine aminopeptidase in urine by univariate study led to a method involving pretreatment of urine with Sephadex G50. Re-examination of the optimization by multivariate study led us to recommend higher optimal concentrations: 5.8 mmol/L for the substrate and 300 mmol/L for the Tris buffer. Under these new conditions, pretreatment of urine was no longer necessary and the assay could be completely automated.

Developing Optimum Drug Regimens

1976 ◽  
Vol 4 (5) ◽  
pp. 277-280
Author(s):  
Michael S Carey ◽  
Robert W Noyes ◽  
Samuel A Pasquale ◽  
John J Frey ◽  
John S Lawson
Keyword(s):  
Response Surface ◽  
Surface Analysis ◽  
Dose Response ◽  
Response Surface Analysis ◽  
Human Experimentation ◽  
Substantial Saving ◽  
Drug Regimens

In Clinical pharmacological trials the determination of the optimum regimen for a drug using the technique of response surface analysis is proposed as being more advantageous than traditional analyses of dose response relationships. Major considerations in favour of this technique are that the optimum regimen can be identified with a minimum of human experimentation, and unacceptable regimens are eliminated from the study early, at a substantial saving of time and money.

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