scholarly journals COVID-19 in Libya: Immunity and Protective Measures?

Author(s):  
Moftah Hussin Alhagamhmad ◽  
Ahmad Abdulkader ◽  
Saleh Megil

Coronavirus Disease 2019 (COVID-19) is a pandemic illness and so far, there are almost 8860331 confirmed infected cases worldwide concentrating mainly in Americas and Europe, whereas data are less prominent in African countries. In Libya, the preliminary reports revealed there are small numbers of COVID-19 confirmed cases, which subsequently showed only a steady rise with no yet a clear explanation. In way we might find a reason behind Libya having a relatively small number of COVID-19 cases, the literature therefore was searched for all relevant journal articles and published reports that dealt with COVID-19 outbreaks. According to the latest released data, the incidence rate of COVID-19 in Libya remained relatively low as compared to the other countries, where only 571 out of almost nine millions total confirmed cases across the globe were documented in Libya. Further, there is a strong claim that Bacillus Calmette-Guérin (BCG) vaccine, a part of national immunization program of many countries including Libya, might offer at least a partial protection against COVID-19. Cross-protective immunity triggered by other related viral infections is an additional immunological theory might explain the current low trend of COVID-19 epidemic in Libya.

2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Kamel A. Samara ◽  
Hiba J. Barqawi ◽  
Basant H. Aboelsoud ◽  
Moza A. AlZaabi ◽  
Fay T. Alraddawi ◽  
...  

AbstractAnnually, 1.5 million cases of hepatitis A infection occur worldwide. The United Arab Emirates (U.A.E.) has seen a decrease in infection rates and seroprevalence coupled with an increase in the average age of infection. This study aimed to assess the U.A.E. society’s hepatitis A knowledge, and attitudes and vaccination practices, with the applicability of its introduction into the local immunization schedule. A self-administered, 50-item questionnaire was used to collect data from the four most populous cities in the U.A.E., between January and March 2020. A total of 458 responses were collected and analysed using IBM-SPSS-26, R-4.0.0 and Matplotlib-v3.2.1. Females had better attitudes (P = 0.036), practices (P < 0.0005), immunization schedule knowledge (AOR = 3.019; CI 1.482–6.678), and appreciation of the immunization schedule (AOR = 2.141; CI 1.310–3.499). A higher level of perceived knowledge was associated with an actual better knowledge (P < 0.0005), better practices (P = 0.011), and increased willingness to get vaccinated (AOR = 1.988; CI 1.032–3.828). Respondents were more likely to vaccinate their children against HAV if the vaccine were introduced into the National Immunization Program (P < 0.0005). Overall, disease knowledge was lacking but with positive attitudes and poor practices. There is high trust in the National Immunization Program and a potential for improving poor practices through local awareness campaigns.


2011 ◽  
Vol 7 (10) ◽  
pp. 1109-1111 ◽  
Author(s):  
Ramesh Verma ◽  
Pardeep Khanna ◽  
Mohan Bairwa ◽  
Suraj Chawla ◽  
Shankar Prinja ◽  
...  

2013 ◽  
Vol 81 (12) ◽  
pp. 4626-4634 ◽  
Author(s):  
Ediane B. Silva ◽  
Andrew Goodyear ◽  
Marjorie D. Sutherland ◽  
Nicole L. Podnecky ◽  
Mercedes Gonzalez-Juarrero ◽  
...  

ABSTRACTInfections with the Gram-negative bacteriumBurkholderia pseudomallei(melioidosis) are associated with high mortality, and there is currently no approved vaccine to prevent the development of melioidosis in humans. Infected patients also do not develop protective immunity to reinfection, and some individuals will develop chronic, subclinical infections withB. pseudomallei. At present, our understanding of what constitutes effective protective immunity againstB. pseudomalleiinfection remains incomplete. Therefore, we conducted a study to elucidate immune correlates of vaccine-induced protective immunity against acuteB. pseudomalleiinfection. BALB/c and C57BL/6 mice were immunized subcutaneously with a highly attenuated, Select Agent-excludedpurMdeletion mutant ofB. pseudomallei(strain Bp82) and then subjected to intranasal challenge with virulentB. pseudomalleistrain 1026b. Immunization with Bp82 generated significant protection from challenge withB. pseudomallei, and protection was associated with a significant reduction in bacterial burden in lungs, liver, and spleen of immunized mice. Humoral immunity was critically important for vaccine-induced protection, as mice lacking B cells were not protected by immunization and serum from Bp82-vaccinated mice could transfer partial protection to nonvaccinated animals. In contrast, vaccine-induced protective immunity was found to be independent of both CD4 and CD8 T cells. Tracking studies demonstrated uptake of the Bp82 vaccine strain predominately by neutrophils in vaccine-draining lymph nodes and by smaller numbers of dendritic cells (DC) and monocytes. We concluded that protection following cutaneous immunization with a live attenuatedBurkholderiavaccine strain was dependent primarily on generation of effective humoral immune responses.


2013 ◽  
Vol 9 (1) ◽  
pp. 112-114 ◽  
Author(s):  
Maziar Moradi-Lakeh ◽  
Abdoulreza Esteghamati

2015 ◽  
Vol 49 (0) ◽  
Author(s):  
Ana Paula Sayuri Sato

The scope and coverage of the Brazilian Immunization Program can be compared with those in developed countries because it provides a large number of vaccines and has a considerable coverage. The increasing complexity of the program brings challenges regarding its development, high coverage levels, access equality, and safety. The Immunization Information System, with nominal data, is an innovative tool that can more accurately monitor these indicators and allows the evaluation of the impact of new vaccination strategies. The main difficulties for such a system are in its implementation process, training of professionals, mastering its use, its constant maintenance needs and ensuring the information contained remain confidential. Therefore, encouraging the development of this tool should be part of public health policies and should also be involved in the three spheres of government as well as the public and private vaccination services.


2013 ◽  
Vol 28 (9) ◽  
pp. 1283 ◽  
Author(s):  
Young June Choe ◽  
Jae Jeong Yang ◽  
Sue K. Park ◽  
Eun Hwa Choi ◽  
Hoan Jong Lee

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