A Critical Comparison between First- and Second-Generation Cryoballoon for Paroxysmal Atrial Fibrillation Ablation

Author(s):  
Sergio Conti ◽  
Claudio Tondo
2016 ◽  
Vol 2016 ◽  
pp. 1-5 ◽  
Author(s):  
Sergio Conti ◽  
Massimo Moltrasio ◽  
Gaetano Fassini ◽  
Fabrizio Tundo ◽  
Stefania Riva ◽  
...  

Introduction. Cryoballoon (CB) ablation has emerged as a novel treatment for pulmonary vein isolation (PVI) for patients with paroxysmal atrial fibrillation (PAF). The second-generation Arctic Front Advance (ADV) was redesigned with technical modifications aiming at procedural and outcome improvements. We aimed to compare the efficacy of the two different technologies over a long-term follow-up.Methods. A total of 120 patients with PAF were enrolled. Sixty patients underwent PVI using the first-generation CB and 60 patients with the ADV catheter. All patients were evaluated over a follow-up period of 2 years.Results. There were no significant differences between the two groups of patients. Procedures performed with the first-generation CB showed longer fluoroscopy time (36.3±16.8versus14.2±13.5 min, resp.;p=0.00016) and longer procedure times as well (153.1±32versus102±24.8 min, resp.;p=0.019). The overall long-term success was significantly different between the two groups (68.3 versus 86.7%, resp.;p=0.017). No differences were found in the lesion areas of left and right PV between the two groups (resp.,p=0.61and0.57). There were no significant differences in procedural-related complications.Conclusion. The ADV catheter compared to the first-generation balloon allows obtaining a significantly higher success rate after a single PVI procedure during the long-term follow-up. Fluoroscopy and procedural times were significantly shortened using the ADV catheter.


2020 ◽  
Vol 41 (Supplement_2) ◽  
Author(s):  
K Ukita ◽  
A Kawamura ◽  
H Nakamura ◽  
K Yasumoto ◽  
M Tsuda ◽  
...  

Abstract Background Little has been reported on the outcome of contact force (CF)-guided radiofrequency catheter ablation (RFCA) and second generation cryoballoon ablation (CBA). Purpose The purpose of this study was to compare the outcome of CF-guided RFCA and second generation CBA for paroxysmal atrial fibrillation (PAF). Methods We enrolled the consecutive 364 patients with PAF who underwent initial ablation between September 2014 and July 2018 in our hospital. We compared the late recurrence of atrial tachyarrhythmia more than three months after ablation between RFCA group and CBA group. All RFCA procedures were performed using CF-sensing catheter and all CBA procedures were performed using second generation CB. Results There were significant differences in background characteristics: chronic kidney disease, serum brain natriuretic peptide level, and left ventricular ejection fraction. After propensity score matched analysis (Table), atrial tachyarrhythmia free survival was significantly higher in CBA group than in RFCA group (Figure). Conclusions Second generation CBA showed a significantly lower late recurrence rate compared to CF-guided RFCA. Kaplan-Meier Curve Funding Acknowledgement Type of funding source: None


2016 ◽  
Vol 27 (6) ◽  
pp. 677-682 ◽  
Author(s):  
VALENTINA DE REGIBUS ◽  
GIACOMO MUGNAI ◽  
DARRAGH MORAN ◽  
BURAK HÜNÜK ◽  
ERWIN STRÖKER ◽  
...  

2018 ◽  
Vol 2 (47) ◽  
pp. 16-21
Author(s):  
Grzegorz Hordyński ◽  
Agnieszka Wojdyła-Hordyńska

Since the release of the second-generation cryoballoon (CB2; Arctic Front AdvanceTM, Medtronic Inc) and its modifications with improved cooling characteristics, the technique, dosing, and complication profile is significantly different from that of the first-generation cryoballoon. Several reports of CB2 procedural recommendations have been presented. Hereby, the literature summary was performed and the technical and procedural study based regimen delivered. The best practice overview presents large centers contemporary techniques for safer and more effective outcomes and perhaps new approved recommendations for atrial fibrillation treatment.


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