Synthesis, Structure Delineation and Antibacterial Activity Study of Metal (II) Complexes of Schiff Base Derived from Kanamycin and Methyl Ester of Amoxicillin

2015 ◽  
Vol 7 (4) ◽  
pp. 165-180 ◽  
Author(s):  
Narendra Chaudhary ◽  
Parashuram Mishra
2020 ◽  
Vol 75 (3) ◽  
pp. 251-258 ◽  
Author(s):  
Ahmed M. Naglah ◽  
Abd El-Galil E. Amr ◽  
Randa E. Abdel-Mageid ◽  
Elsayed A. Elsayed ◽  
Osama I. Abd El-Salam

AbstractA series of linear tetrapeptides 2–7 and cyclooctapeptedopyridine derivatives 8 and 9, were synthesized using Nα-dinicotinoyl-bis[(l-phenylalaninyl-l-leucyl)hydrazide] 2 as starting material. Acid hydrazide 2 was reacted with aromatic or heterocyclic aldehydes to give Schiff base derivatives 3 and 4, respectively. Additionally, compound 2 was reacted with dicarboxylic acid anhydrides ortetracarboxylic diacid anhydrides to give the corresponding linear diimide carboxamides 5–7, and octapeptide tetraimides 8 and 9, respectively. The synthesized products were elucidated by using spectroscopic evidences and they were evaluated for their antibacterial activity by using streptomycin as reference antibiotic drug.


2014 ◽  
Vol 67 (20) ◽  
pp. 3371-3379 ◽  
Author(s):  
Manas Layek ◽  
Mahendra Ghosh ◽  
Michel Fleck ◽  
Rajat Saha ◽  
Debasis Bandyopadhyay

Polyhedron ◽  
2019 ◽  
Vol 157 ◽  
pp. 326-334 ◽  
Author(s):  
Khalid Mahmood ◽  
Waleed Hashmi ◽  
Hammad Ismail ◽  
Bushra Mirza ◽  
Brendan Twamley ◽  
...  

2014 ◽  
Vol 25 (12) ◽  
pp. 2269-2284 ◽  
Author(s):  
May Lee Low ◽  
Laure Maigre ◽  
Pierre Dorlet ◽  
Régis Guillot ◽  
Jean-Marie Pagès ◽  
...  

2015 ◽  
Vol 27 (9) ◽  
pp. 3440-3444
Author(s):  
Habib Hussain ◽  
Syeda Rubina Gilani ◽  
Farkhanda Jabeen ◽  
Zulfiqar Ali ◽  
Hajira Rehman ◽  
...  

Author(s):  
B. Akila ◽  
A. Xavier

Schiff base synthesized from 2-hydroxy-1-naphthaldehyde and 2-2’ (ethylene dioxy) bis ethylenediamine (L1) and its Metal complexes, [M (II) (L)6](where M= Mn(II), Ru(III), Cu(II)and V(V) L= Schiff base moiety), have been prepared and characterized by elemental analysis, spectroscopic measurements (infrared, electronic spectroscopy, 1H-NMR, EPR and Mass spectroscopy ). Elemental analysis of the metal complexes was suggested that the stoichiometry ratio is 1:1 (metal-ligand). The electronic spectra suggest an octahedral geometry for MC1and MC2 Schiff base complexes and distorted octahedral for MC3 and MC4 complexes. The Schiff base and its metal chelates have been screened for their invitro test antibacterial activity against three bacteria, gram-positive (Staphylococcus aureus) and gram-negative (Klebsiella pheneuammonia and Salmonella typhi). Two strains of fungus (Aspergillus niger and Candida albicans). The metal chelates were shown to possess more anti fungal activity compare then antibacterial activity and antioxidant properties. The complexes are highly active than the free Schiff-base ligand.    


2019 ◽  
Vol 19 (2) ◽  
pp. 405
Author(s):  
Agung Pratama ◽  
Firman Sebayang ◽  
Rumondang Bulan Nasution

Cellulose and chitosan are natural polymers that have been used as biocomposite. The aim of this research is to obtain biofilms from chitosan and oxidized cellulose crosslinks. This research is divided into three steps, i.e., isolation of cellulose from oil palm trunk and oxidation of cellulose using NaIO4 (0.2; 0.4; 0.6; 0.8; 1.0 mg/mL) to obtain dialdehyde cellulose (DAC), crosslink of oxidized cellulose with chitosan (DD = 72.85%) to obtain biofilm of chitosan/DAC (CDAC), and characterization of biofilms. The crosslinked reaction was confirmed by FT-IR analysis that showed the spectrum of Schiff base C=N group at 1651 cm–1. Tensile strength increased gradually when the NaIO4 concentration used was 0.2–0.6 mg/mL, but after those concentrations, the tensile strength slightly decreased. The morphology analysis showed that CDAC had smoother morphology than DAC, which was shown rough and showed some particle indicated the presence of unreacted cellulose. CDAC biofilms that prepared with 1.0 mg/mL NaIO4 showed the greatest antibacterial activity.


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