scholarly journals Minimally Invasive Treatment of Pilonidal Disease: Crystallized Phenol and Laser Depilation

2013 ◽  
Vol 97 (4) ◽  
pp. 288-292 ◽  
Author(s):  
Mustafa Girgin ◽  
Burhan Hakan Kanat ◽  
Refik Ayten ◽  
Ziya Cetinkaya ◽  
Zekiye Kanat ◽  
...  

Abstract Pilonidal disease has been treated surgically and by various other methods for many years. The most important problem associated with such treatment is recurrence, but cosmetic outcome is another important issue that cannot be ignored. Today, crystallized phenol is recognized as a treatment option associated with good medical and cosmetic outcomes. We hypothesized that the addition of laser depilation to crystallized phenol treatment of pilonidal disease might increase the rate of success, and this study aimed to determine if the hypothesis was true. Patients who were treated with crystallized phenol and 755-nm alexandrite laser depilation were retrospectively analyzed. In total, 42 (31 male and 11 female) patients were treated with crystallized phenol and alexandrite laser depilation and were followed up between January 2009 and January 2012. In all, 38 patients (90.5%) had chronic disease and 4 (9.5%) had recurrent disease. Among the patients, 26 (61.9%) recovered following 1 crystallized phenol treatment, and the remaining patients had complete remission following repeated treatment. Some patients needed multiple treatments, even up to 8 times. None of the patients had a recurrence during a mean 24 months (range, 6–30 months) of follow-up. Whatever method of treatment is used for pilonidal disease, hair cleaning positively affects treatment outcome. The present results support the hypothesis that the addition of laser depilation (which provides more permanent and effective depilation than other methods) to crystallized phenol treatment (a non-radical, minimally invasive method associated with very good cosmetic results) can increase the effectiveness of the treatment and also reduce the recurrence rate of the disease.

2020 ◽  
pp. 39-51
Author(s):  
G. V. Rodoman ◽  
I. R. Sumedi ◽  
N. V. Sviridenko ◽  
T. I. Shalaeva ◽  
M. M. Meloyan

At present, patients with recurrent nodular goiter account for a significant portion of patients operated on for nodular goiter. At the same time, the comorbid background characteristic of this age group and the technical difficulties of the intervention on cicatricial tissues of the neck cause a high risk of complications of the operation, 3–7 times higher than with primary thyroid interventions. The aim of the study was to evaluate the effectiveness and safety of treatment of recurrent nodular goiter using an alternative minimally invasive method — sclerotherapy. The study included 30 patients previously operated on for nodular goiter. All had 4 courses of sclerotherapy, each included 5 sessions with a frequency of 1 session per week, followed by a follow-up period of 3 months. Polydocanol was used as a sclerosant. The analysis showed that sclerotherapy for recurrent nodular goiter allows all patients to reduce recurrent nodular formations, and in almost a third of cases, complete reduction of the nodes. On average, the decrease in the volume of thyroid residues was 9.6 ± 1.5 ml, and the size of nodular formations decreased by 17.2 ± 1.3 mm (3.7 times — from 23.6 ± 1.4 mm to 6.4 ± 0.7 mm, P <0.001). Nodes more than 3 cm, initially 19 %, ceased to be detected after the third course of sclerotherapy. In all cases, managed to eliminate hormonal imbalances in patients who initially had functional autonomy, as well as signs of compression of the neck organs. At the same time, sclerotherapy of nodules of the thyroid gland using polydocanol as a sclerosant is a safe minimally invasive treatment method, is not accompanied by severe pain and the risk of hypoparathyroidism and laryngeal paresis.


2019 ◽  
Vol 178 (3) ◽  
pp. 69-73
Author(s):  
I. A. Nechai ◽  
N. P. Maltcev

The objective was to compare the most common methods of minimally invasive treatment of pilonidal disease and to evaluate their effectiveness according to the literature. Minimally invasive methods of treatment could be successfully used in patients with a small spread of pilonidal disease. Improving the effectiveness of treatment of this category of patients was directly related to the strict selection of patients.


2021 ◽  
Vol 38 (SI-1) ◽  
pp. 56-60
Author(s):  
Ayşegül İDİL SOYLU ◽  
Fatih UZUNKAYA ◽  
Ümit BELET ◽  
Hüseyin AKAN

Transarterial embolization (TAE) is a minimally invasive treatment method developed alternative to surgery for acute gastrointestinal bleeding (AGIB). The aim of this study was to evaluate the efficacy and outcome of TAE in AGIB patients. The data of 30 patients who underwent TAE with complaint of AGIB between January 2007- May 2020 was collected retrospectively. The etiology of hemorrhage, localization and type of lesion, embolizing agent used, and postprocedural complications were recorded. Lesions were classified as pseudoaneurysm (PA), extravasation, pathological tumor vascularity and vasospasm. A total of 22 patients, 5 females, were included in the study. The most common underlying cause was tumors (n=15, 50%). The most common lesion detected on angiograms was pathological tumor vascularity. Embolizing agents used were Nbutyl-2-cyanoacrylate in five patients, coils in three patients, polyvinyl alcohol particles in six patients and microsphere in seven patients. The technical success rate was 90.9%, and two patients developed rebleeding in the early postprocedural period. TAE is a safe, effective and minimally invasive method in emergency treatment of patients with AGIB.


2021 ◽  
Vol 20 (3) ◽  
pp. 124-133
Author(s):  
E. V. Anikanova ◽  
G. P. Guens ◽  
K. B. Kolontarev ◽  
S. A. Muslov

Recently, minimally invasive treatment modalities based on the application of various physical factors have been widely used in anticancer therapy. Electrochemical lysis is a method in which tumor cells are destroyed by local exposure to a constant low voltage electric current.Purpose: to present the current results of using electrochemical lysis in the treatment of various tumors, to describe the mechanism of tumor destruction and methods of delivering electric current to the tumor, as well as to evaluate the electrical parameters and positioning of the electrodes.Material and Methods.aliterature search included the Medical literatureanalysis and Retrieval system Online (Medline), the excerpta Medica data Base (embase), Web of science, scopus, Russian citation index. All articles were published before december 2019. The review included studies on the investigation electrochemical lysis in vitro, in vivo, as well as clinical observations and clinical studies in which electrochemical lysis has been used as an independent treatment, or in combination with other methods of anticancer treatment since 1984.Results. This review provides information regarding the electrochemical mechanisms of tumor destruction, anti-tumoral effects of electrochemical therapy, methodology for planning and distributing the dose of electrical lysis and positioning of electrodes. We have evaluated complications and oncological results. Electrochemical lysis is a safe, simple, effective, and relatively non-invasive method of antitumor treatment.Conclusion. The electrochemical lysis is a promising minimally invasive method which can be used for the treatment of tumors. However, long-term data are needed to validate this treatment before it can be included into clinical recommendation for the treatment of cancer patients.


2012 ◽  
Vol 76 (1) ◽  
pp. 81-84 ◽  
Author(s):  
Ömer Topuz ◽  
Selim Sözen ◽  
Mustafa Tükenmez ◽  
Sezgin Topuz ◽  
Ümit Erkan Vurdem

Author(s):  
Süleyman Kargın ◽  
Osman Doğru ◽  
Ersin Turan

Objective: The most important cause of post-treatment recurrence in the pilonidal sinus is the re-entry of hair into the skin. The study aimed to investigate the effect of hair removal and its duration on the prevention of recurrences after crystallized phenol treatment. Subject and Methods: The patients with pilonidal sinus disease who were treated with crystallized phenol treatment were evaluated. Hair in the sacrococcygeal area were removed with depilatory cream before every crystallized phenol procedure, during the treatment, and after treatment once a month for six years. Of 1016 patients, 735 were contacted by telephone or e-mail regarding the frequency of sacrococcygeal hair removal and recurrence. Demographic and sinus features and crystallized phenol application data of patients treated with crystallized phenol for pilonidal sinus disease, as well as recurrences were retrospectively assessed. Results: The mean follow-up time was 46.23 ± 33 (range, 11–240) months, with 139 (18.9%) patients experiencing recurrence. Patients who underwent hair removal experienced significantly less recurrence than those who did not (p = 0.003, odds ratio (OR): 0.54 [0.36–0.82]). The OR of recurrence decreased by 0.8% every month as the hair removal time increased (OR = 0.992, 95% CI = 0.985-1.000, p = 0.049). The cut-off value for sensitivity was 0.636, specificity 0.466, and area under the curve 0.562 in hair removal procedures that lasted for over 30 months. Conclusion: Regular hair removal during and at least 30 months after crystallized phenol treatment reduced recurrences in patients with pilonidal sinus disease.


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