Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a novel inflammatory central nervous system disorder. The diagnosis is made on the basis of the radiological, neurological, neuropathological data and responsiveness to steroids treatment. The aim of this paper is to present a neuropsychological characteristic of cognitive, executive and linguistic symptoms characteristic for patient with CLIPPERS disease.
In this paper we present the case of a 42-year-old woman with hyperintense punctate foci in the pons, cerebellum, midbrain, thalamus, white matter of occipital lobes, with a short-term verbal memory deficits, mild deficiency in verbal and procedural learning, executive dysfunctions, hand-eye coordination impairment, psychomotor speed disabilities and dysarthria, associated with a chronic lymphocytic inflammation.
In this challenging diagnosis of CLIPPERS, neuropsychological analysis of cognitive functions can be important to optimize the diagnosis and treatment.