NEUROPSYCHOLOGICAL CHARACTERISTIC OF COGNITIVE DISORDERS IN PATIENT WITH CLIPPERS SYNDROME

2020 ◽  
Vol 18 (3) ◽  
pp. 393-401
Author(s):  
Barbara Peda ◽  
Dariusz Kotlęga ◽  
Marta Masztalewicz

Chronic lymphocytic inflammation with pontine perivascular enhancement responsive to steroids (CLIPPERS) is a novel inflammatory central nervous system disorder. The diagnosis is made on the basis of the radiological, neurological, neuropathological data and responsiveness to steroids treatment. The aim of this paper is to present a neuropsychological characteristic of cognitive, executive and linguistic symptoms characteristic for patient with CLIPPERS disease. In this paper we present the case of a 42-year-old woman with hyperintense punctate foci in the pons, cerebellum, midbrain, thalamus, white matter of occipital lobes, with a short-term verbal memory deficits, mild deficiency in verbal and procedural learning, executive dysfunctions, hand-eye coordination impairment, psychomotor speed disabilities and dysarthria, associated with a chronic lymphocytic inflammation. In this challenging diagnosis of CLIPPERS, neuropsychological analysis of cognitive functions can be important to optimize the diagnosis and treatment.

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
K. Krysta ◽  
A. Klasik ◽  
M. Janas-Kozik ◽  
J. Przybylo ◽  
I. Krupka-Matuszczyk

In schizophrenia there are specific cognitive deficits including verbal memory deficits. The objective of this study was to examine short-term verbal memory differences between subjects with and without a dual diagnosis.A group of 80 patients with a diagnose of schizophrenia were examined. 40 of them never used illicit drugs, the other 40 also received a diagnose of addiction to psychoactive substances. The Free Recall Method was used to compare two examined groups. The results of addicted and not addicted schizophrenic patients were analyzed in all trials of the 5 stages of the examination with the use of Free Recall Method. Persons suffering from schizophrenia can usually repeat much fewer words in all five stages of the examination with Free Recall Method. This deficiency of short-term memory in this group of subjects is present from the very beginning of information coding.As it was expected a deficiency in short-term verbal memory was found in all examined patients. However when comparing both groups no statistical differences concerning verbal memory deficits were found between the group of patients suffering from schizophrenia addicted and not addicted to psychoactive substances.The fact that no significant differences concerning short-term verbal memory between two examined groups were found, which is consistent with some of the studies found in the literature, may be a good predictor for this group in terms of their possible chances of successful rehabilitation.


2005 ◽  
Vol 59 (5) ◽  
pp. 527-532 ◽  
Author(s):  
KANAE SAWAMURA ◽  
YOSHIFUMI NAKASHIMA ◽  
MASAYUKI INOUE ◽  
HIROSHI KURITA

2009 ◽  
Vol 24 (S1) ◽  
pp. 1-1
Author(s):  
K. Krysta ◽  
A. Klasik ◽  
M. Janas-Kozik ◽  
J. Przybylo ◽  
I. Krupka-Matuszczyk

In schizophrenia there are specific cognitive deficits including verbal memory deficits. The objective of this study was to examine short-term verbal memory differences between subjects with and without a dual diagnosis.A group of 80 patients with a diagnose of schizophrenia were examined. 40 of them never used illicit drugs, the other 40 also received a diagnose of addiction to psychoactive substances. The Free Recall Method was used to compare two examined groups. The results of addicted and not addicted schizophrenic patients were analyzed in all trials of the 5 stages of the examination with the use of Free Recall Method. Persons suffering from schizophrenia can usually repeat much fewer words in all five stages of the examination with Free Recall Method. This deficiency of short-term memory in this group of subjects is present from the very beginning of information coding.As it was expected a deficiency in short-term verbal memory was found in all examined patients. However when comparing both groups no statistical differences concerning verbal memory deficits were found between the group of patients suffering from schizophrenia addicted and not addicted to psychoactive substances.The fact that no significant differences concerning short-term verbal memory between two examined groups were found, which is consistent with some of the studies found in the literature, may be a good predictor for this group in terms of their possible chances of successful rehabilitation.


2008 ◽  
Author(s):  
Karen Lau ◽  
Casey Hoffman ◽  
Christiane Burnett ◽  
Kristin Samuelson

2014 ◽  
Author(s):  
Elizabeth S. Gromisch ◽  
Frederick W. Foley ◽  
Andrew S. Castiglione ◽  
Vance Zemon ◽  
Ralph H. Benedict ◽  
...  

2011 ◽  
Vol 49 (3) ◽  
pp. 368-381 ◽  
Author(s):  
Paul Hoffman ◽  
Elizabeth Jefferies ◽  
Matthew A. Lambon Ralph

2002 ◽  
Vol 55 (2) ◽  
pp. 391-424 ◽  
Author(s):  
Honey L.H. Ng ◽  
Murray T. Maybery

The nature of the mechanisms that code item position in serial short-term verbal recall was investigated with reference to temporal grouping phenomena—effects that arise when additional pauses are inserted in a presented list to form groups of items. Several recent models attempt to explain these phenomena by assuming that positional information is retained by associating items with contextual information. According to two of the models—the Phonological Loop model (Hitch, Burgess, Towse, & Culpin, 1996) and the OSCAR model (Brown, Preece, & Hulme, 2000)—contextual information depends critically on the timing of item presentation with reference to group onset. By contrast, according to the Start-End model (Henson, 1998) and a development from it, which we label the Oscillator-Revised Start-End model (Henson & Burgess, 1997), contextual information is independent of time from group onset. Three experiments examined whether coding of position is time dependent. The critical manipulation was to vary stimulus-onset asynchrony from one group to the next in the same list. Lists of consonants were presented visually, but with vocalization in Experiment 1, auditorily in Experiment 2, and auditorily with articulatory suppression in Experiment 3. The pattern of order errors consistently favoured the predictions of the time-independent models over those of the time-dependent models in that across-group transpositions reflected within-group serial position rather than time from group onset. Errors involving intrusions from previous lists also reflected within-group serial position, thereby extending support for the time-independent models.


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