New Neuroprotective Effect of Lemon IntegroPectin on Neuronal Cellular Model

Lemon IntegroPectin obtained via hydrodynamic cavitation of organic lemon processing waste in water shows significant neuroprotective activity in vitro, as first reported in this study investigating the effects of both lemon IntegroPectin and commercial citrus pectin on cell viability, cell morphology, reactive oxygen species (ROS) production, and mitochondria perturbation induced by treatment of neuronal SH-SY5Y human cells with H2O2. Mediated by ROS, including H2O2 and its derivatives, oxidative stress alters numerous cellular processes, such as mitochondrial regulation and cell signaling, propagating cellular injury that leads to incurable neurodegenerative diseases. These results, and the absence of toxicity of this new pectic substance rich in adsorbed flavonoids and terpenes, suggest further studies to investigate its activity in preventing, retarding, or even curing neurological diseases.

Neuroprotective and Mitoprotective Effects of Lemon IntegroPectin on SH-SY5Y Cells

Lemon IntegroPectin obtained via hydrodynamic cavitation of organic lemon processing waste in water shows significant neuroprotective activity in vitro, as first reported in this study investigating the effects of both lemon IntegroPectin and commercial citrus pectin on cell viability, cell morphology, reactive oxygen species (ROS) production and mitochondria perturbation induced by treatment of neuronal SH-SY5Y human cells with H2O2. Mediated by ROS including H2O2 and its derivatives, oxidative stress alters numerous cellular processes, including mitochondrial regulation and cell signaling, propagating cellular injury that leads to incurable neurodegenerative diseases. These results, and the absence of toxicity of this new pectic substance rich in adsorbed flavonoids and terpenes, support further investigations to verify its activity in preventing, retarding, or even curing neurological diseases.

Localisation et comportement du mycélium de Taphrina deformans dans le mésophylle et sous la cuticule des feuilles de pêcher (Prunus persica)

The mycelium of Taphrina deformans (Berk) Tul. stands beneath the cuticule in the layer of pectic substance which spreads over the cellulosic wall of epidermic cells.It also runs within the mesophyll in the amorphous substance of pectic nature which is localized along the ridges of cells and is probably the initium of the middle lamella. This structure often remains incomplete in parasitized leaves.Hyphae do not seem to attack cellulosic walls, cuticule, or pectic substance. They seem to progress chiefly by physical means.

Structural investigation of the galactan component of the pectic substance from Carica papaya

A galactan was isolated in 98% purity from the pectic substance isolated from the unripe fruit of papaya (Carica papaya). Hydrolysis of the fully methylated galactan gave 2,3,4-tri-, 2,3,6-tri-, and 2,3,4,6- tetra-O-methyl-D-galaotose in a mole ratio of 18 : 38 : 1. The structure of galactan is discussed in the light of the results of methylation and periodate oxidation studies.