Chapter 3 discusses the history and scope of Christian (and other) missions that provide medical, surgical, nursing, and dental care and environmental health development through extensive programs of global outreach on six continents. These include partnerships with nongovernmental organizations, government agencies, academic institutions, and secular foundations and philanthropies. The chapter also lays out a historical timeline for the emergence of the pastoral care field, with an emphasis on healthcare chaplaincy. From pioneers such as Richard Cabot and Anton Boisen, in the 1920s and 1930s, through establishment of key organizations and institutions like the Association of Professional Chaplains, the Association for Clinical Pastoral Education, and the HealthCare Chaplaincy Network, this history is traced with an emphasis on clinical, educational, and scholarly developments that have shaped the profession to the present day. Newer professional innovations such as faith-based psychotherapy are also discussed.