Abstract
BackgroundTraditional Chinese medicine (TCM) gives people an image of its medicinal resources all from within China. Nevertheless, the fact is that the Exotic Materia Medica(ECM) has been used in Chinese medicine from Zhou Dynasty (1029 BC-221 AD). However, no extensive studies have focused on it. Now, the high exchange speed of information and material brings TCM opportunities to apply exotic resources in clinics. So, surveying the historical ECM’s resources and medical information is valuable.MethodsWe investigated the origin of 8980 Chinese Materia Medica’s resources included in Chinese Materia Medica and compiled a species list of exotic Chinese medicines (ECM) used in China between 1029 BC–1999 AD and their medical information, introduction time, introduction routes, and place of origin.ResultsConsequently, we found information on 788 ECM and their clinical application. A total of 99% of ECM were found to be botanicals mainly belonging to Solanaceae, Amaranthaceae, Malvaceae, Myrtaceae, and Cruciferae. The exchange speed of these medicines between China and other regions peaked in the Han (206 BC–220 AD), Tang (618–907 AD), and Ming dynasties (1368–1644 AD), and increased sharply from 1912 onwards. The main registered efficacies of the ECM were "clear heat" and diuresis. The most efficient way to convert foreign medicine to TCM is to absorb drugs from foreign regions directly. Last but not least, about One-fifth of commonly used TCM in the clinic is ECM.ConclusionChinese doctors are more concerned with the efficacy of the drug when using it in clinical settings than whether the drug comes from afar. The record of origin and source was to ensure the supply and quality of the drugs. The use of foreign resources as Chinese medicine is the fact that Chinese medicine objectively exists. The existence of ECM has enriched the resources of TCM. Furthermore, both foreign medicine and local medicine currently protect people's lives and health.