The comparative estimation of variability cytogenetic parameters at seed progeny of pine ordinary from ecologically favorable and from industrial (Novolipetsk metallurgical combine - «NLMK») regions is carried out. It is established, that in progeny of pine trees growing in territory of «NLMK» there is an essential change of cytogenetic parameters in comparison with the control. It has been revealed that among seed progeny there are «mutable» and «low-mutable» forms. Questions of adaptation of seed progeny of pine ordinary trees to stressful factors at cellular and sub cellular levels are discussed.