Study on the Effect of Varun Twak Lepa in Management of Vyanga

Vyanga is a disease, which decreases the glowing complexion of the face and affects the skin. Among many diseases concerned with the cosmetic values, Vyanga is common disease one of them known to us from thousands of years. Acharya Sushruta and Vagbhatta has mentioned Vyanga as Kshudra Roga. Though it is considered as Kshudra Roga(minor disease), but it has got a major importance as a cosmetic problem in the society. Vyanga can be correlated with melasma, it is the common pigmentary disorder characterised by symmetrical hyper pigmented macules on face. Aim-To study on the effect of Varun Twak Lepa in management of Vyanga. In this study, the trial drugs used were Varun Twak Lepa for topical application. Material and methods- A total 40 patients of Vyanga were selected from OPD and IPD of Kayachikitsa. Observation and results- To study the effect of Varun Twaka Lepa assessment of patient were done on the basis of MSI score. In all three types, dermal, epidermal and mixed significant result was found on 20th and 30th day. In comparison of three types of melasma more significant result was found in epidermal type.

The study on association of co-morbidities in female patients with vitiligo

<p class="abstract"><strong>Background:</strong> Vitiligo is an acquired pigmentary disorder of skin characterized by the presence of depigmented patches and macules. Vitiligo has been found to be associated with certain autoimmune diseases like diabetes and hypothyroidism. This study is done to evaluate the association of certain co-morbidities with vitiligo in female patients. The aim of the study was to assess the association of vitiligo with co-morbidities in female vitiligo patients and to find the familial association.</p><p class="abstract"><strong>Methods:</strong> Retrospective hospital-based study done over a period of 6 months.<strong></strong></p><p class="abstract"><strong>Results:</strong> In this study series of 75 cases, 19% of cases were associated with hypertension, 25% were associated with diabetes mellitus, 15% were associated with hypothyroidism and positive family history was noted in 17% patients. The mean age of presentation was 43.18.</p><p class="abstract"><strong>Conclusions:</strong> We found a high association of co-morbidities among female patients with vitiligo. In our study, diabetes has been found to be more commonly associated with vitiligo than other comorbidities. Hence screening for co-morbidities should be considered in vitiligo patients.</p>