Iterative learning NARMA-L2 control for turbofan engine with dynamic uncertainty in flight envelope

Nonlinear control of turbofan engines in the flight envelope has attracted much attention in consideration of the inherent nonlinearity of the engine dynamics. Most nonlinear control design techniques rely on the correction theory of reference model parameter to extend the typical flight operations from ground operation. However, dynamic uncertainties in flight envelope lead to the deviation of operating state, and it is negative to control performance. This article is to develop online correction neural network–based speed control approaches for the turbofan engine with dynamic uncertainty in the flight envelope. Two improved online correction nonlinear ways combined with nonlinear autoregressive moving average (NARMA) are proposed, such as gradient search nonlinear autoregressive moving average with feedback linearization (NARMA-L2) control and iterative learning NARMA-L2 control. The contribution of this article is to provide better control quality of fast regulation and less steady errors of engine speed by the proposed methodology in comparison to the conventional NARMA-L2 control. Some important results are reached on both turbofan engine controller design and dynamic uncertainty tolerance at the typical flight operations, and the numerical examples demonstrate the superiority of the proposed control in the flight envelope.

Significance of individual management plan for the patients with hereditary lymphangioedema during pregnancy and lactation, and in newborns

Hereditary angioedema (HAE) is a genetically caused orphan disease with a high risk of developing life-threatening attacks, thus requiring availability for up-to-date information on this problem for the doctors of any specialties. A limited number of observations determine the value of the analysis for each clinical case. Many facets of clinical manifestations, a list of predisposing and triggering factors, as well as limitations of some diagnostic and therapeutic algorithms, require the development of individual management schemes under distinct clinical situations. In this paper, we present the unique clinical cases with certain limitations, describing unexpected onset of the disease in the course of pregnancy, management aspects during delivery and post-delivery periods in a women with a previously confirmed HAE diagnosis. Adapted diagnostic algorithms of postnatal diagnostic verification are presented for children with burdened genetic history. We express some assumptions about involvement of a multidisciplinary team of specialists, personalized approach to building a management plan with an “online” correction depending on observation stage of НАЕ patient.