This chapter explores ambition for power in politics and the workplace. Control over others can be advantageous in its own right and also in the wealth and recognition that it often confers. Although most politicians link their need for power to the service of public interests, the evidence often suggests otherwise. Drawing on prominent examples, such as Lyndon Johnson, Richard Nixon, John McCain, and Donald Trump, and those who served them, the chapter explores how prioritizing power can subvert principle and the institutional checks necessary to prevent abuse. By contrast, examples such as Nelson Mandela show how those who use power to empower others can serve the highest ideals of social justice. Power in the workplace can also serve stakeholder and societal interests, but it is too often sabotaged by egoistic interests, needs for control, and bullying behaviors. The chapter concludes with strategies to increase accountability for abusive conduct.