Urinary Mercury Levels and Predictors of Exposure among a Group of Italian Children

Urinary mercury (Hg) levels are suitable to assess long-term exposure to both elemental and inorganic Hg. In this study, the urinary Hg levels of 250 children (aged 6–11 years) from three areas with different anthropogenic impacts in the Rieti province, central Italy, were assessed. The Hg concentrations were in the range of 0.04–2.18 µg L−1 with a geometric mean equal to 0.18 µg L−1 [95% confidence interval (CI), 0.17–0.20 µg L−1] or 0.21 µg g−1 creatinine (95% CI, 0.19–0.23 µg g−1 creatinine), and a reference value calculated as 95th percentile of 0.53 µg L−1 (95% CI, 0.44–0.73 µg L−1) or 0.55 µg g−1 creatinine (95% CI, 0.50–0.83 µg g−1 creatinine). In all cases, urinary Hg data were below the HBM-I values (7 µg L−1 or 5 µg g−1 creatinine) established for urine, while the 95th percentile was above the German Human Biomonitoring Commission’s RV95 (0.4 µg L−1) set for children without amalgam fillings. A significant correlation (p < 0.05) was found between creatinine-corrected results and residence area, with higher urinary Hg levels in children living in the industrial area. Multiple linear regression analysis showed that creatinine was the main predictor of urinary Hg.

Measuring mercury in urine among students & professors at the faculty of dentistry exposed to mercury vapor by cold vapor atomic absorption technique

Introduction: Dentists are exposed to mercury vapor due to the occupational exposure to amalgam, which can endanger their health. The aim of this study was to determine the effect of mercury vapor on urinary mercury concentration of dental students and the restorative specialists in one of the dental schools of Iran. Methods: The study population consisted40 dental students and 10 restoration specialists. Sample urine at the end of work time was collected, and the concentration of mercury in urine was measured by cold vapor atomic absorption spectrophotometry. A questionnaire was completed to determine the effects of some personal and environmental factors on the amount of urinary mercury. Data were analyzed using SPSS-22 software. Results: The mean concentration of urinary mercury in dental students was 15.18±4.34μg/L and the restoration specialists were 4.11±1.05μg/l. In addition, there was a significant difference between the concentrations of urinary mercury in the two groups (P <0.001). At specialist professors there was a negative correlation between urinary mercury and working hours per day (r=-0.78, p=0.007). Also, in this study, there was a significant relationship between urine mercury and sex, age, type of amalgam consumed, consumption of smoking and the number of amalgam restorations. Conclusion: The level of urine mercury in all samples was lower the recommended amount of ACGIH. The study is recommended mercury level monitoring for regularly evaluation of the workplace.

The exposure and toxic effects of mercury in gold mining activities

Background: Mercury is used by artisanal — small-scale (ASM) gold miners throughout the World. In 2014, the Sudanese government produced over 60 tons of gold, which make Sudan ranked Africa's third-largest gold miner. Also, Sudan is ranked the 15th global producer. In 2015, over 1 million miners participated in gold mining and extraction. Objective: This study aimed to determine mercury health risk in Sudanese traditional gold mining activities area. Method: This is an analytical cross-sectional observational stud. The studied population was from ALTWAHEN near ABUHAMED. Urine analysis was supported by epidemiological questionnaires designed by (EPI INFO software) following WHO guidelines. Eighty-six respondents completed the questionnaire. The mercury level was determined in 58 urine sample by Petroleum Laboratories Using Direct Mercury Analyzer DMA- 80 instrument. The epidemiological data were analyzed by (EPI INFO). Result: 98% exceed concentration of 100 ug/L which contaminated concentration for occasionally exposed, mean urinary mercury concentration 2785 ug/L, the highest mercury concentration worldwide reported by our study 10250 ug/L, Symptoms in 58 patient showed as Problem finding correct word 46.6%, memory problem 27.6%, problem with thinking clearly 29.3%, nervousness 31%, sadness 46.5%, sexual problem 36.2%, headache 51.7%, excessive salivation 43%, drowsy 48.3%. Conclusion: In this study, the highest urinary mercury concentration was reported (10250 ug/L) compared to other studies. Mercury concentration with no significant difference between the miner groups and others. Also, this study found high incidents of neurological symptoms associated with neurotoxicity. The problem with thinking significantly correlated to the age weighted by mercury concentration. Only tremor significantly related to the time living in the mining area. Otherwise, no significant relationship between mercury concentration ,symptoms and time living in the area. Recommendation: conducting Interventional study by using chelation therapy, Gold miners should use safety tools, Activation of laws and conventions (MINAMATA convention).