flow cytometry study
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2018 ◽  
Vol 95 (2) ◽  
pp. 214-218 ◽  
Author(s):  
Natália Aydos Marcondes ◽  
Silvia Resende Terra ◽  
Camila Serina Lasta ◽  
Nicole Regina Capacchi Hlavac ◽  
Magnus Larruscaim Dalmolin ◽  
...  

2018 ◽  
Vol 64 (6) ◽  
pp. 525-529 ◽  
Author(s):  
Natália Marcondes ◽  
Flavo Fernandes ◽  
Gustavo Faulhaber

SUMMARY OBJECTIVE: Ki-67 is a nuclear protein associated with cellular proliferation in normal or leukemic conditions that can help identify more aggressive diseases and is usually evaluated with immunohistochemistry. The aim of this was to assess Ki-67 expression on mature B-cell neoplasms samples with flow cytometry immunophenotyping. METHOD: After surface staining with CD19 and CD45, intracellular staining for Ki-67 was performed in leukemic mature B-cells. Ki-67 expression was evaluated with flow cytometry. RESULTS: Ki-67 expression was higher in mantle cell lymphoma, Burkitt lymphoma, and diffuse large B-cell lymphoma cases. It was also associated with CD38 mean fluorescence intensity. CONCLUSIONS: Ki-67 expression evaluated by flow cytometry can be a useful tool in the diagnosis of mature B-cell neoplasms. More studies are needed to validate Ki-67 assessment with flow cytometry immunophenotyping.


2018 ◽  
Vol 59 (9) ◽  
pp. 2242-2245 ◽  
Author(s):  
Vincenzo Cosimato ◽  
Giulia Scalia ◽  
Maddalena Raia ◽  
Laura Gentile ◽  
Vincenza Cerbone ◽  
...  

2017 ◽  
Vol 33 (3) ◽  
pp. 172-182 ◽  
Author(s):  
A. A. Tykhomyrov ◽  
D. D. Zhernossekov ◽  
T. V. Grinenko

Materials ◽  
2017 ◽  
Vol 10 (5) ◽  
pp. 481 ◽  
Author(s):  
Monika Lukomska-Szymanska ◽  
Magdalena Konieczka ◽  
Beata Zarzycka ◽  
Barbara Lapinska ◽  
Janina Grzegorczyk ◽  
...  

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