Half-curcumin analogues as PET imaging probes for amyloid beta species

In this report, we demonstrate that half-curcuminoid could be a better scaffold for PET tracer development.

Tuning the stereo-hindrance of a curcumin scaffold for the selective imaging of the soluble forms of amyloid beta species

We demonstrate that tuning the stereo-hindrance of the phenoxy-alkyl chains at the 4-position of a curcumin scaffold could lead to certain selectivity for soluble Aβs over insoluble Aβs.