BAN2401 SHOWS STRONGER BINDING TO SOLUBLE AGGREGATED AMYLOID-BETA SPECIES THAN ADUCANUMAB

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Linda Söderberg ◽  
Hanna Laudon ◽  
Charlotte Sahlin ◽  
Malin Johannesson ◽  
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Michael T Heneka
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We demonstrate that tuning the stereo-hindrance of the phenoxy-alkyl chains at the 4-position of a curcumin scaffold could lead to certain selectivity for soluble Aβs over insoluble Aβs.


PLoS ONE ◽  
2011 ◽  
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Chongzhao Ran ◽  
Wei Zhao ◽  
Robert D. Moir ◽  
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