Introduction. Cystic dystrophy of the duodenal wall is a rare complication of
the ectopic pancreas that is characterized by cyst/s formation within
thickened duodenal wall. Case Outline. A 61?year?old male with recurrent
abdominal pain, weight loss (about 25 kg) who had been moderate alcohol
abuser and heavy smoker was presented. On ultrasonography, very thickened
duodenal wall (2.5 cm), an enlarged head of the pancreas with cyst of 3 cm in
diameter as well as dilated pancreatic duct (<6 mm) were seen. Barium meal
showed stenosis of the first and second part of the duodenum. CT and
endoscopic ultrasound confirmed the ultrasonographic finding. The patient
underwent surgery. The pathologic finding was established only on first two
portions of the duodenum and limited part of the head of the pancreas along
duodenum while the rest of the pancreas was normal. Due to poor general
condition, gastrojejunostomy was performed. Although some improvement was
evident, the patient did not become asymptomatic, and, therefore, four months
later a cephalic duodenopancreatectomy was carried out which made him fully
asymptomatic. A year later, the patient was symptom?free and in good health.
Histologic examination showed a cystic dystrophy of the duodenal wall in
the ectopic pancreas. Conclusion. Unless there are strong contraindications,
cephalic duodenopancreatectomy is best treatment of the disease.