Sorption of Pharmaceuticals in Aqueous Solution Using Insoluble β-Cyclodextrin Polymers

The present study was aimed at evaluating the ability of insoluble β-cyclodextrin polymers (βCDps) to recover pharmaceuticals from aqueous solutions. Two different β-cyclodextrin polymers, one composed of epichlorohydrin-cross linked β-cyclodextrin and the other a β-cyclodextrin-polyurethane, were prepared by condensation polymerization and addition polymerization of βCD using epichlorohydrin (EP) and diisocyanatohexane (HDI) as cross linking agents, respectively. The contaminants tested were naphthalene, naproxen, nabumetone, 2-naphthol, pyrene and propranolol which represent model pharmaceutical molecules. The adsorption isotherms of the organics and βCDPs were well described by Freundlich isotherm equations. The trapping efficiencies were determined using fluorescence spectroscopy as the analytical technique. Based on the results of this study, it was found that the epichlorohydrin-cross linked β-cyclodextrin polymers were more efficient in adsorption of organic contaminants both in batch and column systems when compared with β-cyclodextrin-polyurethane polymers. Reasons for these differences are discussed.

Sorption of Pharmaceuticals in Aqueous Solution Using Insoluble β-Cyclodextrin Polymers

The present study was aimed at evaluating the ability of insoluble β-cyclodextrin polymers (βCDps) to recover pharmaceuticals from aqueous solutions. Two different β-cyclodextrin polymers, one composed of epichlorohydrin-cross linked β-cyclodextrin and the other a β-cyclodextrin-polyurethane, were prepared by condensation polymerization and addition polymerization of βCD using epichlorohydrin (EP) and diisocyanatohexane (HDI) as cross linking agents, respectively. The contaminants tested were naphthalene, naproxen, nabumetone, 2-naphthol, pyrene and propranolol which represent model pharmaceutical molecules. The adsorption isotherms of the organics and βCDPs were well described by Freundlich isotherm equations. The trapping efficiencies were determined using fluorescence spectroscopy as the analytical technique. Based on the results of this study, it was found that the epichlorohydrin-cross linked β-cyclodextrin polymers were more efficient in adsorption of organic contaminants both in batch and column systems when compared with β-cyclodextrin-polyurethane polymers. Reasons for these differences are discussed.

Coordination-induced polymerization of P═C bonds leads to regular (P─C)n polycarbophosphanes

The replacement of carbon in (C─C)n chains of polyolefins by phosphorus leads to polycarbophosphanes (P─C)n, which may possess unique chemical and physical properties. However, macromolecules with a regular (P─C)n chain have never been unambiguously identified. Here, we demonstrate that addition polymerization, a general concept to polymerize olefins, can be extended to P═C double bonds. The polymerization of monomeric 2-phosphanaphthalenes is mediated by copper(I) halides and leads to polycarbophosphanes with an Mn of 14 to 34 kDa. Each phosphorus is coordinated to Cu(I), which can be easily removed. Unlike long-term durable polyolefins, the metal-free polymers depolymerize rapidly back to monomers under sunlight or ultraviolet irradiation at λ = 365 nm. The monomers can be recycled for repolymerization, demonstrating a cradle-to-cradle life cycle for polycarbophosphanes.

Highly efficient vinylic addition polymerization of 5-vinyl-2-norbornene using benzylic palladium complexes as precatalysts

A very small amount of a palladium benzylic complex as initiator brings about the vinylic addition polymerization of the reluctant 5-vinyl-2-norbornene.

Graphene @ framework polymer derived from addition polymerization of phthalocyanine/dicarboxaldehyde as a negative material for lithium-ion batteries

A novel grid framework polymer (BDC-NiPc) is synthesized by the addition polymerization of tetraamino-substituted nickel phthalocyanine with 4,4'-biphenyl dicarboxaldehyde. The obtained BDC-NiPc shows very low solubility in organic electrode solvents...