Clinicopathological and dermoscopic correlation of pigmented basal cell carcinoma

Basal cell carcinoma (BCC), also known as basal cell epithelioma is the most common cutaneous malignancy affecting fair skinned individuals arising from sun exposed skin especially head and neck area. It is a slow growing tumor which rarely metastasizes. UV radiation is the most important predisposing factor. It includes mainly four variants: (a) nodular, (b) pigmented, (c) superficial BCC, (d) sclerosing or morphea form of which most common is nodular variant. Dermoscopy of pigmented BCC shows well focussed arborizing vessels which is the hallmark. The best modality of treatment is surgical excison of tumour, electrodesiccation and curettage, cryosurgery, and Mohs micrographic surgery.

Study of Biochemical and Hematological Markers in Patients Diagnosed with Basal Cell Carcinoma

In recent years, numerous scientific research papers have focused on the analysis of immunological, biochemical, ultrastructural, molecular and genetic factors that govern the clinical aspects of basal cell carcinomas. This retrospective study was carried out in the Clinical Department of Dermatovenerology at the County Emergency Clinical Hospital “Sf. Apostol Andrei”, Constanta. The research included a total of 140 patients treated in the clinic, with a diagnosis of basal cell epithelioma. We analyzed several biochemical and hematological markers including creatinine, male HDL cholesterol, female HDL cholesterol, LDL cholesterol, urea, serum glucose. More than half of patients with BCC present data of possible hepatic impairment and high atherogenic risk.

BASAL CELL EPITHELIOMA PADA ANJING PERSILANGAN

Basal cell epithelioma adalah tumor jinak pada membrana basalis sel epitel kulit, yang belum diketahui penyebabnya secara pasti. Tumor ini bisa menyerang pada semua ras anjing baik jantan maupun betina dan umumnya ditemukan pada anjing yang berumur tua. Seekor anjing persilangan berumur tiga tahun, bobot badan 6,8 kg dan berjenis kelamin bertina diperiksa di Rumah Sakit Hewan Pendidikan, Fakultas Kedokteran Hewan, Universitas Udayana dengan keluhan adanya benjolan disertai tukak pada bagian bawah leher. Secara fisik anjing teramati seakan-akan sehat dengan napsu makan dan minum baik, defikasi dan urinasi normal. Hasil pemeriksaan histopatologis jaringan yang dilakukan di Balai Besar Veteriner Denpasar, terdapat bentukan seperti pita (garland) pada jaringan tumor tersebut, sehingga anjing didiagnosis menderita basal cell epithelioma dengan prognosis fausta. Anjing ditangani dengan melakukan pembedahan (eksisi) untuk mengangkat masa tumor pada bagian leher dan pemberian antibiotika cepotaxim dengan analgesik asam mefenamat. Satu minggu pascaoperasi anjing dinyatakan sembuh dengan luka operasi yang sudah kering dan menyatu.

Electron Microscopy Study of Nodular Basal Cell Carcinoma

The electron microscopic study represent the changes in the skin layers in the malignant tumor, the nodular basal cell epithelioma. Comparisons were made between normal cells found in the normal skin at the periphery of the tumor, the cells located near the tumor and the tumors located in the depth of the carcinoma. The microscopic analysis of the tumor formation revealed the characteristics of the pigmented nodular basal cell epitheliu. To the exterior of the carcinoma were evidenced numerous globular formations limiting the peripheral extension of the tumor, which explains its evolution in years.

The Evolution of Biochemical Indices After Basal Cell Epithelioma Removal - Case Report

The paper proposes new exposure data on etiopathogenesis basal cell epithelioma and present a clinical case investigated dermatoscopic, biochemically, treated surgically and guided to avoid relapses. The case presented is part of typical cases of pigmented basal cell carcinoma. Biochemical and haematological investigations performed one day before the excisional intervention (results 1) and 30 days (results 2) after the intervention: It is recommended to monitor biochemical investigations in which alterations were found, and ways for raising the immunological status.