Let [Formula: see text] be a simple and undirected graph with vertex set [Formula: see text]. A set [Formula: see text] is called a dominating set of [Formula: see text], if every vertex in [Formula: see text] is adjacent to at least one vertex in [Formula: see text]. The minimum cardinality of a dominating set of [Formula: see text] is called the domination number of [Formula: see text], denoted by [Formula: see text]. A dominating set [Formula: see text] of [Formula: see text] is called isolate dominating, if the induced subgraph [Formula: see text] of [Formula: see text] contains at least one isolated vertex. The minimum cardinality of an isolate dominating set of [Formula: see text] is called the isolate domination number of [Formula: see text], denoted by [Formula: see text]. In this paper, we show that for every proper interval graph [Formula: see text], [Formula: see text]. Moreover, we provide a constructive characterization for trees with equal domination number and isolate domination number. These solve part of an open problem posed by Hamid and Balamurugan [Isolate domination in graphs, Arab J. Math. Sci. 22(2) (2016) 232–241].