Simulated and experimental force spectroscopy of lysozyme on silica

Force-distance curves of proteins detaching from oxide surfaces measured by atomic force microscopy are interpreted with atomic-scale models which reveal the significance of disulfide and hydrogen bond patterns on the protein stability.

A phenol-fused tetrathiafulvalene: modulation of hydrogen-bond patterns and electrical conductivity in the charge-transfer salt

Elimination of one hydroxy group from a tetrathiafulvalene derivative changed hydrogen-bond patterns in the charge-transfer salt, leading to improved conductivity.

Diphenylalanine in tetrahydrofuran: a highly potent candidate for the development of novel nanomaterials

The peptide di-L-phenylalanine (FF) has emerged as a highly potent candidate for the development of novel nanomaterials. The unprotected peptide was dissolved in 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP) mixed with tetrahydrofuran (THF) and single crystals of the THF monosolvate, C18H20N2O3·C4H8O, were grown by slow evaporation in a `vial-in-closed-bottle' system. THF is a molecule that can only act as a hydrogen-bond acceptor. Thus, the hydrogen-bond patterns observed in the crystal structures at 100 and 299 K are different compared to that of crystals grown from water and methanol [Mason et al. (2014). ACS Nano. 8, 1243–1253].

Trimethyl-, triethyl- and trimethoxybenzene-based tripodal compounds bearing pyrazole groups: conformations and halogen-/hydrogen-bond patterns in the crystalline state

X-ray analyses of a series of benzene-based tripodal molecules1–9provide interesting insights into the molecular recognition phenomena and give information about the different conformations which adopt the molecules in the solvent-free crystals and in solvates.