application ontology
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2021 ◽  
Vol ahead-of-print (ahead-of-print) ◽  
Author(s):  
Ummul Hanan Mohamad ◽  
Mohammad Nazir Ahmad ◽  
Ahmad Mujahid Ubaidillah Zakaria

PurposeThis systematic literature review (SLR) paper presents the overview and analysis of the existing ontologies application in the SE domain. It discusses the main challenges in terms of its ontologies development and highlights the key knowledge areas for subdomains in the SE domain that provides a direction to develop ontologies application for SE systematically. The SE is not as straightforward as the traditional economy. It transforms the existing economy ecosystem through peer-to-peer collaborations mediated by the technology. Hence, the complexity of the SE domain accentuates the need to make the SE domain knowledge more explicit.Design/methodology/approachFor the review, the authors only focus on the journal articles published from 2010 to 2020 and mentioned ontology as a solution to overcome the issues specific for the SE domain. The initial identification process produced 3,326 papers from 10 different databases.FindingsAfter applying the inclusion and exclusion criteria, a final set of 11 articles were then analyzed and classified. In SE, good ontology design and development is essential to manage digital platforms, deal with data heterogeneity and govern the interoperability of the SE systems. Yet the preference to build an application ontology, lack of perdurant design and minimal use of the existing standard for building SE common knowledge are deterring the ontology development in this domain. From this review, an anatomy of the SE key subdomain areas is visualized as a reference to further develop the domain ontology for the SE domain systematically.Originality/valueWith the arrival of the Fourth Industrial Revolution (4IR), the sharing economy (SE) has become one of the important domains whose impact has been explosive, and its domain knowledge is complex. Yet, a comprehensive overview and analysis of the ontology applications in the SE domain is not available or well presented to the research community.


2021 ◽  
Vol 5 ◽  
Author(s):  
Mónica D. Ramírez-Andreotta ◽  
Ramona Walls ◽  
Ken Youens-Clark ◽  
Kai Blumberg ◽  
Katherine E. Isaacs ◽  
...  

Environmental contamination is a fundamental determinant of health and well-being, and when the environment is compromised, vulnerabilities are generated. The complex challenges associated with environmental health and food security are influenced by current and emerging political, social, economic, and environmental contexts. To solve these “wicked” dilemmas, disparate public health surveillance efforts are conducted by local, state, and federal agencies. More recently, citizen/community science (CS) monitoring efforts are providing site-specific data. One of the biggest challenges in using these government datasets, let alone incorporating CS data, for a holistic assessment of environmental exposure is data management and interoperability. To facilitate a more holistic perspective and approach to solution generation, we have developed a method to provide a common data model that will allow environmental health researchers working at different scales and research domains to exchange data and ask new questions. We anticipate that this method will help to address environmental health disparities, which are unjust and avoidable, while ensuring CS datasets are ethically integrated to achieve environmental justice. Specifically, we used a transdisciplinary research framework to develop a methodology to integrate CS data with existing governmental environmental monitoring and social attribute data (vulnerability and resilience variables) that span across 10 different federal and state agencies. A key challenge in integrating such different datasets is the lack of widely adopted ontologies for vulnerability and resiliency factors. In addition to following the best practice of submitting new term requests to existing ontologies to fill gaps, we have also created an application ontology, the Superfund Research Project Data Interface Ontology (SRPDIO).


JAMIA Open ◽  
2021 ◽  
Author(s):  
Shyam Visweswaran ◽  
Malarkodi J Samayamuthu ◽  
Michele Morris ◽  
Griffin M Weber ◽  
Douglas MacFadden ◽  
...  

Abstract Clinical data networks that leverage large volumes of data in electronic health records (EHRs) are significant resources for research on coronavirus disease 2019 (COVID-19). Data harmonization is a key challenge in seamless use of multisite EHRs for COVID-19 research. We developed a COVID-19 application ontology in the national Accrual to Clinical Trials (ACT) network that enables harmonization of data elements that that are critical to COVID-19 research. The ontology contains over 50,000 concepts in the domains of diagnosis, procedures, medications, and laboratory tests. In particular, it has computational phenotypes to characterize the course of illness and outcomes, derived terms, and harmonized value sets for SARS-CoV-2 laboratory tests. The ontology was deployed and validated on the ACT COVID-19 network that consists of nine academic health centers with data on 14.5M patients. This ontology, which is freely available to the entire research community on GitHub at https://github.com/shyamvis/ACT-COVID-Ontology, will be useful for harmonizing EHRs for COVID-19 research beyond the ACT network.


Data ◽  
2021 ◽  
Vol 6 (4) ◽  
pp. 41
Author(s):  
Stella Markantonatou ◽  
Katerina Toraki ◽  
Panagiotis Minos ◽  
Anna Vacalopoulou ◽  
Vivian Stamou ◽  
...  

We present AΜAΛΘΕΙA (AMALTHIA), an application ontology that models the domain of dishes as they are presented in 112 menus collected from restaurants/taverns/patisseries in East Macedonia and Thrace in Northern Greece. AΜAΛΘΕΙA supports a tourist mobile application offering multilingual translation of menus, dietary and cultural information about the dishes and their ingredients, as well as information about the geographical dispersion of the dishes. In this document, we focus on the food/dish dimension that constitutes the ontology’s backbone. Its dish-oriented perspective differentiates AΜAΛΘΕΙA from other food ontologies and thesauri, such as Langual, enabling it to codify information about the dishes served, particularly considering the fact that they are subject to wide variation due to the inevitable evolution of recipes over time, to geographical and cultural dispersion, and to the chef’s creativity. We argue for the adopted design decisions by drawing on semantic information retrieved from the menus, as well as other social and commercial facts, and compare AMAΛΘΕΙA with other important taxonomies in the food field. To the best of our knowledge, AΜAΛΘΕΙA is the first ontology modeling (i) dish variation and (ii) Greek (commercial) cuisine (a component of the Mediterranean diet).


2021 ◽  
Author(s):  
Shyam Visweswaran ◽  
Malarkodi J Samayamuthu ◽  
Michele Morris ◽  
Griffin M Weber ◽  
Douglas MacFadden ◽  
...  

Clinical data networks that leverage large volumes of data in electronic health records (EHRs) are significant resources for research on coronavirus disease 2019 (COVID-19). Data harmonization is a key challenge in seamless use of multisite EHRs for COVID-19 research. We developed a COVID-19 application ontology in the national Accrual to Clinical Trials (ACT) network that enables harmonization of data elements that that are critical to COVID-19 research. The ontology contains over 50,000 concepts in the domains of diagnosis, procedures, medications, and laboratory tests. In particular, it has computational phenotypes to characterize the course of illness and outcomes, derived terms, and harmonized value sets for SARS-CoV-2 laboratory tests. The ontology was deployed and validated on the ACT COVID-19 network that consists of nine academic health centers with data on 14.5M patients. This ontology, which is freely available to the entire research community on GitHub at https://github.com/shyamvis/ACT-COVID-Ontology, will be useful for harmonizing EHRs for COVID-19 research beyond the ACT network.


2021 ◽  
Vol 22 (1) ◽  
Author(s):  
Anna Maria Masci ◽  
◽  
Scott White ◽  
Ben Neely ◽  
Maryanne Ardini-Polaske ◽  
...  

Abstract Background Immunofluorescent confocal microscopy uses labeled antibodies as probes against specific macromolecules to discriminate between multiple cell types. For images of the developmental mouse lung, these cells are themselves organized into densely packed higher-level anatomical structures. These types of images can be challenging to segment automatically for several reasons, including the relevance of biomedical context, dependence on the specific set of probes used, prohibitive cost of generating labeled training data, as well as the complexity and dense packing of anatomical structures in the image. The use of an application ontology helps surmount these challenges by combining image data with its metadata to provide a meaningful biological context, modeled after how a human expert would make use of contextual information to identify histological structures, that constrains and simplifies the process of segmentation and object identification. Results We propose an innovative approach for the semi-supervised analysis of complex and densely packed anatomical structures from immunofluorescent images that utilizes an application ontology to provide a simplified context for image segmentation and object identification. We describe how the logical organization of biological facts in the form of an ontology can provide useful constraints that facilitate automatic processing of complex images. We demonstrate the results of ontology-guided segmentation and object identification in mouse developmental lung images from the Bioinformatics REsource ATlas for the Healthy lung database of the Molecular Atlas of Lung Development (LungMAP1) program Conclusion We describe a novel ontology-guided approach to segmentation and classification of complex immunofluorescence images of the developing mouse lung. The ontology is used to automatically generate constraints for each image based on its biomedical context, which facilitates image segmentation and classification.


10.2196/21434 ◽  
2020 ◽  
Vol 6 (4) ◽  
pp. e21434 ◽  
Author(s):  
Simon de Lusignan ◽  
Harshana Liyanage ◽  
Dylan McGagh ◽  
Bhautesh Dinesh Jani ◽  
Jorgen Bauwens ◽  
...  

Background Creating an ontology for COVID-19 surveillance should help ensure transparency and consistency. Ontologies formalize conceptualizations at either the domain or application level. Application ontologies cross domains and are specified through testable use cases. Our use case was an extension of the role of the Oxford Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) to monitor the current pandemic and become an in-pandemic research platform. Objective This study aimed to develop an application ontology for COVID-19 that can be deployed across the various use-case domains of the RCGP RSC research and surveillance activities. Methods We described our domain-specific use case. The actor was the RCGP RSC sentinel network, the system was the course of the COVID-19 pandemic, and the outcomes were the spread and effect of mitigation measures. We used our established 3-step method to develop the ontology, separating ontological concept development from code mapping and data extract validation. We developed a coding system–independent COVID-19 case identification algorithm. As there were no gold-standard pandemic surveillance ontologies, we conducted a rapid Delphi consensus exercise through the International Medical Informatics Association Primary Health Care Informatics working group and extended networks. Results Our use-case domains included primary care, public health, virology, clinical research, and clinical informatics. Our ontology supported (1) case identification, microbiological sampling, and health outcomes at an individual practice and at the national level; (2) feedback through a dashboard; (3) a national observatory; (4) regular updates for Public Health England; and (5) transformation of a sentinel network into a trial platform. We have identified a total of 19,115 people with a definite COVID-19 status, 5226 probable cases, and 74,293 people with possible COVID-19, within the RCGP RSC network (N=5,370,225). Conclusions The underpinning structure of our ontological approach has coped with multiple clinical coding challenges. At a time when there is uncertainty about international comparisons, clarity about the basis on which case definitions and outcomes are made from routine data is essential.


2020 ◽  
Author(s):  
Simon de Lusignan ◽  
Harshana Liyanage ◽  
Dylan McGagh ◽  
Bhautesh Dinesh Jani ◽  
Jorgen Bauwens ◽  
...  

BACKGROUND Creating an ontology for COVID-19 surveillance should help ensure transparency and consistency. Ontologies formalize conceptualizations at either the domain or application level. Application ontologies cross domains and are specified through testable use cases. Our use case was an extension of the role of the Oxford Royal College of General Practitioners (RCGP) Research and Surveillance Centre (RSC) to monitor the current pandemic and become an in-pandemic research platform. OBJECTIVE This study aimed to develop an application ontology for COVID-19 that can be deployed across the various use-case domains of the RCGP RSC research and surveillance activities. METHODS We described our domain-specific use case. The actor was the RCGP RSC sentinel network, the system was the course of the COVID-19 pandemic, and the outcomes were the spread and effect of mitigation measures. We used our established 3-step method to develop the ontology, separating ontological concept development from code mapping and data extract validation. We developed a coding system–independent COVID-19 case identification algorithm. As there were no gold-standard pandemic surveillance ontologies, we conducted a rapid Delphi consensus exercise through the International Medical Informatics Association Primary Health Care Informatics working group and extended networks. RESULTS Our use-case domains included primary care, public health, virology, clinical research, and clinical informatics. Our ontology supported (1) case identification, microbiological sampling, and health outcomes at an individual practice and at the national level; (2) feedback through a dashboard; (3) a national observatory; (4) regular updates for Public Health England; and (5) transformation of a sentinel network into a trial platform. We have identified a total of 19,115 people with a definite COVID-19 status, 5226 probable cases, and 74,293 people with possible COVID-19, within the RCGP RSC network (N=5,370,225). CONCLUSIONS The underpinning structure of our ontological approach has coped with multiple clinical coding challenges. At a time when there is uncertainty about international comparisons, clarity about the basis on which case definitions and outcomes are made from routine data is essential.


2020 ◽  
Author(s):  
Anna Maria Masci ◽  
Scott White ◽  
Ben Neely ◽  
Maryanne Ardini-Polaske ◽  
Carol B. Hill ◽  
...  

AbstractBackgroundImmunofluorescent confocal microscopy uses labeled antibodies as probes against specific macromolecules to discriminate between multiple cell types. For images of the developmental mouse lung, these cells are themselves organized into densely packed higher-level anatomical structures. These types of images can be challenging to segment automatically for several reasons, including the relevance of biomedical context, dependence on the specific set of probes used, prohibitive cost of generating labeled training data, as well as the complexity and dense packing of anatomical structures in the image. The use of an application ontology surmounts these challenges by combining image data with its metadata to provide a meaningful biological context, and hence constraining and simplifying the process of segmentation and object identification.ResultsWe propose an innovative approach for the automated analysis of complex and densely packed anatomical structures from immunofluorescent images that utilizes an application ontology to provide a simplified context for image segmentation and object identification. We describe how the logical organization of biological facts in the form of an ontology can provide useful constraints that enhance automatic processing of complex images. We demonstrate the results of ontology-guided segmentation and object identification in mouse developmental lung images from the Bioinformatics REsource ATlas for the Healthy lung (BREATH) database of the Molecular Atlas of Lung Development (LungMAP1) program.ConclusionThe microscopy analysis pipeline library (micap) is available at https://github.com/duke-lungmap-team/microscopy-analysis-pipeline. Code to reproduce our analysis of LungMAP images is also available at https://github.com/duke-lungmap-team/lungmap-pipeline. Finally, the application ontology is available at https://github.com/duke-lungmap-team/lung_ontology and includes example SPARQL queries.ContactAnna Maria Masci email: [email protected]


Author(s):  
Ning Wang

As existing methods cannot express, share, and reuse the digital evidence review information in a unified manner, a solution of digital evidence review elements knowledge base model based on ontology is presented. Firstly, combing with the multi-source heterogeneous characteristic of digital evidence review knowledge, classification and extraction are accomplished. Secondly, according to the principles of ontology construction, the digital evidence review elements knowledge base model which includes domain ontology, application ontology, and atomic ontology is established. Finally, model can effectively acquire digital evidence review knowledge by analyzing review scenario.


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