A spectrofluorimetric study of the limbal area in patients with primary open-angle glaucoma

Purpose: to evaluate hypoxic changes in the limbus area conjunctiva of patients with primary open-angle glaucoma (POAG) treated with prolonged instillations of prostaglandin (PG) analogs. Material and methods. A spectrofluorimetric study of the limbus zone was carried out in 202 patients aged 56–87 years with POAG in the developed and advanced stages, divided into 2 groups. Group 1 consisted of patients aged 69.4 ± 10.3 years who received beta-blockers (BB) and carbonic anhydrase inhibitors (ICA) for 5–10 months; of these, 39 (30.2 %) had a developed stage of POAG and 90 (69.7 %) had advanced POAG. Group 2, aged 72.3 ± 9.4, received PG analogs, in addition to BB and ICA, for 5–10 months. In this group, 21 (28.7 %) patients had developed POAG and 52 (71.23 %) had advanced POAG. Results. The patients who received PG instillations showed a significantly higher ratio of fluorescence intensity in the wavelength range of 410/520 nm NADH/FAD (0.352 ± 0.043) than those receiving no such therapy (0.319 ± 0.047), which can be interpreted as a hypoxic state of the limbus area. Conclusion. Spectrofluorimetric testing of POAG patients taking PG analogs can be useful for detecting ischemia in the limbus area, because this category of patients are very likely to form cicatricial changes in the area of the filtration cushion in the early postoperative period after antiglaucomatous interventions.

Hospital Based Longitudinal Study on Artificial Snow Spray Induced Ocular Injuries and Its Correlation with the Awareness among the Study Population at Medical College Hospital, Bhubaneswar

BACKGROUND Artificial snow spray induced ocular injuries have become common in the past two decades throughout India. There is a paucity of studies in India as well as globally on such injuries. This study was undertaken to identify such types of ocular injuries and evaluate the awareness of artificial snow spray use in the present hospital settings. METHODS This hospital based longitudinal study was carried out among 68 patients having artificial snow spray induced ocular injuries. The study period was from 01. 01. 2019 to 30. 12. 2019. A detailed history of patients was taken pertaining to the injury. A thorough ocular examination was carried out on a slit lamp biomicroscope. Visual acuity was recorded using Snellen’s test type chart. Clinical grading was done by Roper Hall classification. RESULTS The present study included 68 patients i.e. 124 eyes of which 64.7 % (44) were males, 35.3 % (24) were females. The mean age was 26.029 years. All the patients suffered from chemical conjunctivitis (100 %), superficial punctate keratitis (SPK) 82.3 %, corneal erosion (8.8 %), and corneal erosion involving limbal area (3.2 %). Most ocular injuries due to artificial foam were bilateral (82.3 %). Maximum number of patients (94.4 %) had grade I ocular injuries. 93.5 % of patients had BCVA (best corrected visual acuity) 6 / 6 within 1 week of ocular injuries. So far, no patients had any irreversible ophthalmic sequelae. Awareness among the study group was very less. CONCLUSIONS Artificial snow spray used in parties, festival celebration can cause mild to severe ocular injuries. Public awareness will reduce the use of this chemical. KEYWORDS Artificial Snow Spray, Corneal Erosion, Ocular Injury, Awareness

Innovative approach to barrier amnioplasty in surgical treatment of primary progressive pterygium

The aim is to evaluate the efficacy of new method of barrier amnioplasty in surgical treatment of primary progressive pterygium. Materials and methods. 40 patients (40 eyes) with primary progressive pterygium, divided into two groups depending on surgical features of barrier amnionoplasty: in the main group (20 patients), plastic surgery was carried out in the semilunar fold area; in the control group (20 patients) in the limbal area. All patients underwent special examination: tear pH measurement and cytological evaluation of the cellular composition from the wound surface. The treatment efficacy was evaluated: in the early postoperative period by the timing of conjunctival inflammation disappearance, corneal epithelialization and vitalization of the amnion; after 1 year according to the state of the limbus, cornea, visual acuity, degree of corneal astigmatism. Results and conclusions. The use of amnioplasty method in the area of semilunar fold developed and implemented by us in clinical practice showed high efficacy: time reduction in local cellular inflammatory reactions in the cytological composition of swabs and scrapings and postoperative inflammation of ocular surface, which led to shortening of periods of corneal epithelization by 1.7 times and vitalization of the amnion by 1.5 times. Uncomplicated postoperative course of inflammatory-regenerative reactions allows avoiding the pterygium recurrence and causes reduction of the degree of corneal astigmatism and visual acuity increase.

TWO NEW SATYRIDS FROM NORTH AMERICA

Male Length of primaries (measured from the base of the wing to the apex) 25-26 mm. Genitalia identical with those of Minois meadi meadi. Uppe: surface: the primaries as in typical meadi, with two small dark ocelli ringed with light reddish-yellow; the pupils reduced in the anterior ocelli and lacking in the posterior; the area btween the occclli may be suffused with reddish-yellow. Secondaries as in typical meadi, with a well developed submarginal ocellus between veins Cu1 and Cu2, which may or may not be pupilled with while. Lower surface: primaries similar to M. m. meadi. Secondaries with a well developed submarginal ocelllis between Cu1, and Cu2; additional ocelli may also be present between M1 and 2, and Cu1 and 2A. The ground color is homogeneous dull brown, with darker striae which are more sparsely distributed than in typical meadi, and tend to disappear in the limbal area. The dark transverse bands of meadi have almost completclv disappeared.