AbstractIn this work we prove the uniqueness of solutions to the nonlocal linear equation $$L \varphi - c(x)\varphi = 0$$
L
φ
-
c
(
x
)
φ
=
0
in $$\mathbb {R}$$
R
, where L is an elliptic integro-differential operator, in the presence of a positive solution or of an odd solution vanishing only at zero. As an application, we deduce the nondegeneracy of layer solutions (bounded and monotone solutions) to the semilinear problem $$L u = f(u)$$
L
u
=
f
(
u
)
in $$\mathbb {R}$$
R
when the nonlinearity is of Allen–Cahn type. To our knowledge, this is the first work where such uniqueness and nondegeneracy results are proven in the nonlocal framework when the Caffarelli–Silvestre extension technique is not available. Our proofs are based on a nonlocal Liouville-type method developed by Hamel, Ros-Oton, Sire, and Valdinoci for nonlinear problems in dimension two.