Photolytic Irradiation of Pharmaceutical Compound 2 (-4 thaizolyl) benzimidazole

Photolytic irradiation of 2(-4 thiazolyl) benzimidazole in acidic and neutral medium using benzophenone (methyl orange) as sensitizer .Photochemical reactions depend on the source of the reaction. for example Sunlight, UV light and visible light. 2-(-4 thiazoly) benzimidazole(2gm powder) was dissolved in dried and distilled ethyl alcohol (C2H5OH) 200 ml and add 0.01gm sensitizer. The solution mixture was irradiated in presence of 125w and 250 w mercury vapor lamp for around 40 to50 hrs. The progress of the reaction mixture was observed at regular intervals from Thin layer chromatography method every10 hrs. After 41 and 55 hrs two new spots appeared on the plate of TLC. At the end of the reaction two products were found. This products show many pharmaceutical properties like primarily in treatment to control the stomach warm mold and fungal diseases infection, also widely used in (thiabendezole medicine), anti parasitic medicine for treatment of roundworm, hookworm and helminthes

Effect of ionizing radiation on soil bacteria, fungi and germination of red gram seeds (Cajanus cajan L.)

Effect of ionizing radiation on survival of bacteria, fungi and red gram seed (Cajanus cajan L.) germination was assessed in laterite soil in the laboratory. The mercury vapor lamp (l = 400 nm‐700 nm), sodium vapor lamp (l =589.3 nm ) and ultra violet (l = 400 nm ‐ 10 nm) radiations were exposed to the laterite soils for 20, 40, 60 and 80 min and their effect on survival of bacterial, fungal colonies and seed germination were enumerated. Sodium vapor was found to be very effective in inhibiting the bacterial and fungal populations. Ultra violet radiation was efficient in reducing the survival of the microbial densities than mercury vapor lamp. In the exposed soil, the germination of seeds in terms of percentage, the stem length (SL) and root length (RL) of seeds were calculated at 7th day of incubation. The laterite soil was shown significant stimulation in the germination of seed at 40 min exposure with ultra violet radiation. Results obtained in the present study indicate that the energy captivated by molecules was prominent at lower radiation and shorter exposure time enhanced the proliferation of bacterial cells and red gram seed germination.