Research of Phase Behavior in Natural Gas Drive Process and Its Application in T_D Reservoir with HTHP

Different from other gas drive processes, phase behavior performs more significant roles in natural gas drive process. The main reason is that more severe mass transfer effect and similar phase solubility effect have been caused by multicomponent interaction. This paper provides a series of methods to study the phase behavior in natural gas drive process, aiming to reveal further mechanism and give technical supports to the on-site practice in T_D Reservoir with HTHP. Four key parameters of natural gas drive have been determined. Firstly, laboratory compounding method has been improved to obtain real components of formation fluids and actual injected gas at formation condition (140°C, 45MPa). Secondly, 19 sets of slim tube test has been carried to determine MMP (minimum miscible pressure) and the injected gas components ensuring miscibility. Thirdly, swelling test and laser method have been used to separately obtain the viscosity reduction degree and solid deposition effects. Finally, multiple contact test has been carried to describe the miscibility behavior. All the above have been applied in T_D Reservoir. Conclusions could be drawn from the results obtained by the methods above. Firstly, swelling capacity of crude oil could be enhanced by natural gas for the formation volume factor of crude oil in T_D Reservoir increased by 57% and the viscosity decreased by 83% after natural gas injection. Secondly, MMP of dry gas and crude oil in T_D Reservoir is 43.5MPa with a miscible displacement efficiency above 90% (>30% compared with immiscible displacement efficiency), and the content of N2+C1 should be controlled over 88%. Thirdly, results of 5 levels contact experiments shows that miscibility behavior of natural gas and oil from T_D Reservoir performs an evaporative-condensate composite miscible process in which the condensate miscible process takes the lead. Finally, obvious solid point has not been observed in natural gas drive process of crude oil from T_D Reservoir at the formation temperature, and the effect of solid deposition on the fluid flow in formation could be ignored because of trace amount of solid solution (<1mg/ml) and minute formation permeability damage (<8%). The achievements above have been applied in T_D Reservoir as one of the important technical means supporting over 350,000 tons increased production by natural gas drive. A systematic methods have been reorganized to research the phase behavior in natural gas drive process and half of these methods mentioned above get partially improvement. These physical simulation experiments have covered most mainly processes and the key parameters in reservoirs with HTHP and natural gas drive, including mass transfer, viscosity, expansion, volume coefficient, MMP, miscibility behavior and solid deposition. Every experiment gives a quantitative analysis which possesses satisfied practicability in field application.

Analytical Characterization of 3-MeO-PCP and 3-MMC in Seized Products and Biosamples: The Role of LC-HRAM-Orbitrap-MS and Solid Deposition GC-FTIR

Among the phencyclidine (PCP) and synthetic cathinone analogs present on the street market, 3-methoxyphencyclidine (3-MeO-PCP) is one of the most popular dissociative hallucinogen drugs, while 3-methylmethcathinone (3-MMC) is a commonly encountered psychostimulant. Numerous 3-MeO-PCP- and 3-MMC-related intoxication cases have been reported worldwide. Identification of the positional isomers of MeO-PCP and MMC families are particularly challenging for clinical and forensic laboratories; this is mostly due to their difficult chromatographic separation (particularly when using liquid chromatography–LC) and similar mass spectrometric behaviors. 3-MeO-PCP and 3-MMC were identified in two powders, detained by two subjects and seized by the police, by different analytical techniques, including liquid chromatography-high-resolution accurate-mass Orbitrap mass spectrometry (LC-HRAM-Orbitrap-MS), and solid deposition gas chromatography-Fourier transform infrared spectroscopy (sd-GC-FTIR). LC-HRAM-Orbitrap-MS allowed us to assign the elemental formulae C18H27NO (MeO-PCP) and C11H15NO (MMC) through accurate mass measurement of the two MH+ ions, and the comparison of experimental and calculated MH+ isotopic patterns. However, MH+ collision-induced product ions spectra were not conclusive in discriminating between the positional isomers [(3-MeO-PCP vs. 4-MeO-PCP) and (3-MMC vs. 4-MMC and 2-MMC)]. Likewise, sd-GC-FTIR easily allowed us to differentiate between the MeO-PCP and MMC positional isomers unambiguously, confirming the presence of 3-MeO-PCP and 3-MMC, due to the high-quality match factor of the experimental FTIR spectra against the target FTIR spectra of MeO-PCP and MMC isomers in a dedicated library. 3-MeO-PCP (in contrast to 3-MMC) was also detected in blood and urine samples of both subjects and analyzed in the context of routine forensic casework by LC-HRAM-Orbitrap-MS following a simple deproteinization step. In addition, this untargeted approach allowed us to detect dozens of phase I and phase II 3-MeO-PCP metabolites in all biological specimens. Analysis of the extracted samples by sd-GC-FTIR revealed the presence of 3-MeO-PCP, thus confirming the intake of such specific methoxy-PCP isomer in both cases. These results highlight the effectiveness of LC-HRAM-Orbitrap-MS and sd-GC-FTIR data in attaining full structural characterization of the psychoactive drugs, even in absence of reference standards, in both non-biological and biological specimens.

Effect of Accumulative Recycling of Aqueous Phase on the Properties of Hydrothermal Degradation of Dry Biomass and Bio-Crude Oil Formation

For hydrothermal liquefaction of dry biomass to produce liquid fuels, water needs to be added or the aqueous phase products can be recycled. This paper focuses on understanding the relationship between hydrothermal degradation of the dry biomass and oil formation under the condition of accumulative recycling of the aqueous phase. Completely dried corn stalk and deionized water were used for the hydrothermal liquefaction (HTL) experiment. The aqueous products for subsequent recycling were not diluted. It was demonstrated that the recycling of the aqueous can promote the enrichment of organic acids and the conversion of ketones and phenols in the aqueous, improving the yield and quality of Bio-crude oil. After recycling, the yield of Bio-crude oil increased from 20.42% to 24.31% continuously, and the oxygen content decreased from 13.34% to 9.90%. Although the process was accompanied by solid deposition and had a negative impact on the hydrothermal degradation efficiency, the formation of carbon microspheres during the deposition enhanced the utilization of nondegradable solids, while the formation of metal salt particles had a positive impact on oil production. After three rounds of recycling, the solid deposition effect was weakened. At this time, oil production and solids degradation can be promoted simultaneously.