Modulating the boundary layer velocity profile is a very promising strategy for achieving transition delay and reducing the friction of the plate. By perturbing the flow with counter-rotating vortices that undergo transient, non-modal growth, streamwise-aligned streaks are formed inside the boundary layer, which have been proved (theoretical and experimentally) to be very robust flow structures. In this paper, we employ efficient numerical methods to perform a parametric stability investigation of the three-dimensional incompressible flat-plate boundary layer with finite-amplitude streaks. For this purpose, the Boundary Region Equations (BREs) are applied to solve the nonlinear downstream evolution of finite amplitude streaks. Regarding the stability analysis, the linear three-dimensional plane-marching Parabolized Stability Equations (PSEs) concept constitutes the best candidate for this task. Therefore, a thorough parametric study is presented, analyzing the instability characteristics with respect to critical conditions of the modified incompressible zero-pressure-gradient flat-plate boundary layer, by means of finite-amplitude linearly optimal and suboptimal disturbances or streaks. The parameter space is extended from low- to high- amplitude streaks, accurately documenting the transition delay for low-amplitude streaks and the amplitude threshold for streak shear layer instability or bypass transition, which drastically displaces the transition front upstream.