A morphological characterization of the lumbar neural arch in females and males with degenerative spondylolisthesis

Background Although Degenerative Spondylolisthesis (DS) is a common osseous dysfunction, very few studies have examined the bony morphology of lumbar the neural arch in the population afflicted with DS. Therefore, this study aimed to characterize the neural arch (NA) morphology along the entire lumbar spine in individuals with degenerative spondylolisthesis (DS) and compare them to healthy controls. Methods One hundred CTs from a database of 500 lumbar CTs of spondylolisthesis were selected. We excluded vertebral fractures, non-L4-L5 slips, previous surgeries, vertebral spondyloarthropathies, and scoliosis. Scans were divided into a study group of 50 individuals with single-level DS (grades 1–2) at L4–5 (25 males and 25 females), and an age-sex matched control group of 50 individuals. Linear and angular measurements from all lumbar segments included: vertebral canals, intervertebral foramens, pedicles, and articular facets. Results Compared with the controls, all individuals with DS had greater pedicle dimensions in the lower lumbar segments (∆ = 1 mm–2.14 mm) and shorter intervertebral foramens in all the lumbar segments (∆range:1.85 mm–3.94 mm). In DS females, the lower lumbar facets were mostly wider (∆ = 1.73–2.86 mm) and more sagittally-oriented (∆10°) than the controls. Greater prevalence of grade-3 facet arthrosis was found only in the DS population (DS = 40–90%,controls = 16.7–66.7%). In DS males, degenerated facets were observed along the entire lumbar spine (L1-S1), whereas, in DS females, the facets were observed mainly in the lower lumbar segments (L4-S1). Individuals with DS have shorter intervertebral foramens and greater pedicle dimensions compared with controls. Conclusions Females with DS have wider articular facets, more sagittally-oriented facets, and excessively degenerated facets than the controls. This unique NA shape may further clarify DS’s pathophysiology and explain its greater prevalence in females compared to males.

Which hip morphology measures and patient factors are associated with age of onset and symptom severity in femoroacetabular impingement syndrome?

Background: Bony morphology is central to the pathomechanism of femoroacetabular impingement syndrome (FAIS), however isolated radiographic measures poorly predict symptom onset and severity. More comprehensive morphology measurement considered together with patient factors may better predict symptom presentation. This study aimed to determine the morphological parameter(s) and patient factor(s) associated with symptom age of onset and severity in FAIS. Methods: 99 participants (age 32.9 ± 10.5 years; body mass index (BMI 24.3 ± 3.1 kg/m2; 42% females) diagnosed with FAIS received standardised plain radiographs and magnetic resonance scans. Alpha angle in four radial planes (superior to anterior), acetabular version (AV), femoral torsion, lateral centre-edge, anterior centre-edge (ACEA) and femoral neck-shaft angles were measured. Age of symptom onset (age at presentation minus duration of symptoms), international Hip Outcome Tool-33 (iHOT-33) and modified UCLA activity scores were recorded. Backward stepwise regression assessed morphological parameters and patient factors (age, sex, BMI, symptom duration, annual income, private/public healthcare system accessed) to determine variables independently associated with onset age and iHOT-33 score. Results: Earlier symptom onset was associated with larger superoanterior alpha angle ( p = 0.007), smaller AV ( p = 0.023), lower BMI ( p = 0.010) and public healthcare system access ( p = 0.041) (r2 = 0.320). Worse iHOT-33 score was associated with smaller ACEA ( p = 0.034), female sex ( p = 0.040), worse modified UCLA activity score ( p = 0.010) and public healthcare system access ( p < 0.001) (r2 = 0.340). Conclusions: Age of symptom onset was chiefly predicted by femoral and acetabular bony morphology measures, whereas symptom severity predominantly by patient factors. Factors measured explained a small amount of variance in the data; additional unmeasured factors may be more influential.

THREE-DIMENSIONAL PREDICTORS OF FAI DISEASE PROGRESSION IN THE CONTRALATERAL HIP

Background: Bony morphologies contributing to femoroacetabular impingement (FAI) are relatively common in the general population, but drivers of symptom development are not well understood. Hypothesis/Purpose: The purpose of this study was to determine the role of three-dimensional bony morphology in symptom development in the contralateral hip in patients undergoing ipsilateral surgical treatment for FAI. Methods: The study included a prospective cohort of 161 consecutive patients (101 females, 60 males) who presented for ipsilateral FAI surgical treatment from 2013-2018. The average age was 29.1 years. Minimum follow-up was 1 year (mean, 2.3 years; range, 1-6 years). Low-dose CT scans were obtained prior to surgical treatment. Three-dimensional hip analysis of the contralateral hip was performed relative to normative data and allowed measurements of 15 key parameters. Prior to surgery and at routine follow-up, patients completed standardized questionnaires that included pain in the contralateral hip. Univariate and multivariate analyses were performed to identify independent predictors. Results: There were 133 patients (83%) with follow-up. Significant levels of pain in the contralateral hip were reported in 25 (18.8%) patients at presentation and 50 (35.3%) patients at follow-up. Twenty-six (19.5%) patients progressed to surgery at an average of 1.12 years. Significant predictors of symptom development were alpha angle >55° at 1:00 (p=0.037), femoral version <0° or > 20° (p=0.027), and decreased central acetabular version at 3:00 (p=0.048). Significant predictors of surgery were age <30 years (p=0.023) and alpha angle >55° at 1:00 (p=0.005). Conclusion: We found that roughly 1 in 5 patients undergoing surgical treatment for ipsilateral FAI experienced pain in the contralateral hip at presentation, over one third reported pain at follow-up, and 1 in 5 progressed to surgery. Higher alpha angle, abnormal femoral version, and decreased acetabular version were correlated with symptom development, while higher alpha angle and age under 30 were associated with progression to surgery.

Variations in Glenohumeral Bony Morphology May Predict Recurrent Instability after Arthroscopic Bankart Repair

Objectives: Variations in bony anatomy may be associated with failure of stabilization surgery. The aim of this study was to develop a method to measure bony morphology on magnetic resonance imaging (MRI) to identify risk factors for failure after Bankart repair. Methods: This was a retrospective case-control study of 118 patients. Cases of postoperative dislocation were compared to matched controls. Demographic data was obtained by chart review and radiographic data from preoperative MRI. Volume was measured using a 3-D model. Radius of curvature of the humeral head and glenoid was measured on axial MRI images. Statistical analysis used student’s t-test for continuous variables and either Fisher’s exact or Chi-squared test for categorical variables; P value < 0.05 was significant. Interrater reliability between reviewers was calculated using interclass correlation coefficients (r). Results: Forty-six patients who had a postoperative dislocation met inclusion criteria and were matched to 72 controls. There was no difference between groups for demographic (age, sex, percentage of contact athletes) or radiographic (glenoid bone loss, off-track Hill-Sachs lesions) parameters. The average number of preoperative dislocations was higher in the case group (3.2 vs. 2.0, p=0.003). The humeral head (68.8 ml vs 62.8 ml, p=0.05) volume was greater in the case group, though this did not reach statistical significance. Glenoid volume (13.5 ml vs 12.8 ml, p=0.31) was similar between groups. The radius of curvature of the glenoid was larger, or shallower, in the case group compared to the control group (23.6 mm vs 22.6 mm, p=0.05), though the difference did not reach statistical significance. A greater percentage of patients with a glenoid radius of curvature > 24.5 mm experienced a postoperative dislocation compared to those who had a smaller radius of curvature (62.0% vs 29.8%, p < 0.01). In fact, patients who had glenoid radius of curvature > 24.5 mm were 5 times as likely to experience a postoperative dislocation compared to those who did not (odds ratio 5.04, 95% CI 2.13 – 11.94, p < 0.01) There was no significant difference between the number of preoperative dislocations between patients with larger or smaller glenoid radius of curvature (2.6 vs 2.3, p = 0.55). There was a strong interrater reliability for measurement of humeral head volume, glenoid volume, radius of curvature of glenoid and radius of curvature of humeral head (r = 0.94, 0.88, 0.89, 0.95). Conclusion: The results of this study demonstrate that a larger radius of curvature, indicative of a shallower glenoid, is associated with failure following primary arthroscopic Bankart. These findings suggest that the bony concavity of the glenoid may play a role in stability. [Figure: see text]