Investigation of correlation between autoimmune antibodies and real-time ultrasound elastosonography scores in patients with Hashimoto’s Thyroiditis

Objective To investigate the correlation between autoimmune antibodies,ultrasonic elasticity scores,elasticity coefficients in patients with Hashimoto’s thyroiditis.Methods Detected the thyroid function,the thyroid globulin antibody (TgAb) and the titer of thyroid peroxides antibody(TPOAb) by chemiluminescence from the fasting serum of 258 patients suffering with Hashimoto’s thyroiditis; The ultrasonic elasticity scores and elasticity coefficients were evaluated after detecting the patients’ thyroid with GELOGIQ3 type Color Doppler Ultrasound Diagnostic System and getting a satisfactory elastosonography.Then the correlation between autoimmune antibodies,ultrasonic elasticity scores and elasticity coefficients were analyzed respectively.Results Serum thyroid stimulating hormone (TSH),TGA and TPO in 258 patients with HT increased significantly,the titer of TgAb was positively correlated with elastic coefficients,r=0.62,P<0.001,and also positively correlated with elastic scores,r=0.65,P<0.001;TPOAb was positively correlated with elastic coefficients,r=0.63,P<0.001,and positively correlated with elastic scores as well,r=0.62,P<0.001.Conclusions It’s helpful to increase the accuracy rate of HT diagnosis with detection of thyroid autoimmune function combined with Real-time ultrasound elastosonography scores.