alveolar mechanics
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2019 ◽  
Vol 19 (04) ◽  
pp. 1950027
Author(s):  
TIANYA LIU ◽  
YUXING WANG ◽  
XIAOYU LIU ◽  
LAN YUAN ◽  
DEYU LI ◽  
...  

Understanding alveolar mechanics is important for preventing the possible lung injuries during mechanical ventilation. Alveolar clusters with smaller size are found having lower compliance in two-dimensional studies. But the influence of alveolar shape on compliance is unclear. In order to investigate how alveolar morphology affects their behavior, we tracked subpleural alveoli of isolated mouse lungs during quasi-static ventilation using two- and three-dimensional imaging techniques. Results showed that alveolar clusters with smaller size and more spherical shape had lower compliance. There was a better correlation of sphericity rather than circularity with alveolar compliance. The compliance of clusters with great shape change was larger than that with relatively slight shape change. These findings suggest the contribution of lung heterogeneous expansion to lung injuries associated with mechanical ventilation.



2018 ◽  
Vol 124 (2) ◽  
pp. 525-525
Author(s):  
Gary F. Nieman ◽  
Joshua Satalin ◽  
Michaela Kollisch-Singule ◽  
Penny Andrews ◽  
Hani Aiash ◽  
...  


2014 ◽  
Vol 117 (8) ◽  
pp. 937-937 ◽  
Author(s):  
Carrie E. Perlman
Keyword(s):  


2014 ◽  
Vol 202 ◽  
pp. 44-49 ◽  
Author(s):  
Caterina Salito ◽  
Andrea Aliverti ◽  
Ilaria Rivolta ◽  
Enrico Mazzuca ◽  
Giuseppe Miserocchi


2013 ◽  
Vol 41 (5) ◽  
pp. 1374-1375
Author(s):  
Jason H.T. Bates
Keyword(s):  


2013 ◽  
Vol 41 (5) ◽  
pp. 1286-1295 ◽  
Author(s):  
David Schwenninger ◽  
Hanna Runck ◽  
Stefan Schumann ◽  
Jörg Haberstroh ◽  
Hans-Joachim Priebe ◽  
...  




2012 ◽  
Vol 112 (6) ◽  
pp. 935-936 ◽  
Author(s):  
Gary F. Nieman
Keyword(s):  




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