BAHASA RUPA MOTIF BATIK CIAMIS MELALUI PROGRAM LINDENMAYER SYSTEMS

Jawa Barat memiliki sentra perajin rakyat yang banyak memiliki keragaman motif yang diangkat dari potensi kedaerahannya. Salah satu nya adalah batik Ciamis, tetapi kini dengan adanya wabah virus Corona 19 berdampak luar biasa terhadap ekonomi industri makro dan mikro dalam pengembangan usaha batik. Semakin banyak yang menghentikan usahanya. Sehingga dikhawatirkan motif-motif batik Ciamis semakin langka juga di pasaran. Melalui Turtle graphics motif-motif batik yang ada dibuat dalam bentuk citra vektor untuk dilestarikan dengan memanfaatkan teknologi digital. Tujuan dari penelitian ini motif batik Ciamis dapat dibuat bahasa rupa melalui proses digitalisasi menggunakan bahasa pemrograman MuPad. Manfaatnya adalah untuk mendokumentasikan serta memperkenalkan kembali motif Batik Ciamis yang sudah hampir punah. Metode yang digunakan adalah eksperimen digitalisasi melalui Lindenmayer System. Sampel batik Ciamis dipilih motif yang memiliki repetisi dengan pola berulang. Hasil penelitian ini menunjukkan bahwa motif batik Ciamis dapat dibuat dengan teknik lengkungan, garis horisontal dan vertikal, rotasi. Simpulan dari penelitian ini perancangan motif batik dapat menggunakan program Lindenmayer System sebagai blueprint dan dapat diimplementasikan pada batik nusantara. Kontribusi dari penelitian ini, cara pendokumentasian ini dapat diimplementasikan ke industri kreatif.

The DNA walk and its demonstration of deterministic chaos—relevance to genomic alterations in lung cancer

MotivationAdvancements in cancer genetics have facilitated the development of therapies with actionable mutations. Although mutated genes have been studied extensively, their chaotic behavior has not been appreciated. Thus, in contrast to naïve DNA, mutated DNA sequences can display characteristics of unpredictability and sensitivity to the initial conditions that may be dictated by the environment, expression patterns and presence of other genomic alterations. Employing a DNA walk as a form of 2D analysis of the nucleotide sequence, we demonstrate that chaotic behavior in the sequence of a mutated gene can be predicted.ResultsUsing fractal analysis for these DNA walks, we have determined the complexity and nucleotide variance of commonly observed mutated genes in non-small cell lung cancer, and their wild-type counterparts. DNA walks for wild-type genes demonstrate varying levels of chaos, with BRAF, NTRK1 and MET exhibiting greater levels of chaos than KRAS, paxillin and EGFR. Analyzing changes in chaotic properties, such as changes in periodicity and linearity, reveal that while deletion mutations indicate a notable disruption in fractal ‘self-similarity’, fusion mutations demonstrate bifurcations between the two genes. Our results suggest that the fractals generated by DNA walks can yield important insights into potential consequences of these mutated genes.Availability and implementationIntroduction to Turtle graphics in Python is an open source article on learning to develop a script for Turtle graphics in Python, freely available on the web at https://docs.python.org/2/library/turtle.html. cDNA sequences were obtained through NCBI RefSeq database, an open source database that contains information on a large array of genes, such as their nucleotide and amino acid sequences, freely available at https://www.ncbi.nlm.nih.gov/refseq/. FracLac plugin for Fractal analysis in ImageJ is an open source plugin for the ImageJ program to perform fractal analysis, free to download at https://imagej.nih.gov/ij/plugins/fraclac/FLHelp/Introduction.html.Supplementary informationSupplementary data are available at Bioinformatics online.

TURTLE GRAPHICS OF MORPHIC SEQUENCES

The simplest infinite sequences that are not ultimately periodic are pure morphic sequences: fixed points of particular morphisms mapping single symbols to strings of symbols. A basic way to visualize a sequence is by a turtle curve: for every alphabet symbol fix an angle, and then consecutively for all sequence elements draw a unit segment and turn the drawing direction by the corresponding angle. This paper investigates turtle curves of pure morphic sequences. In particular, criteria are given for turtle curves being finite (consisting of finitely many segments), and for being fractal or self-similar: it contains an up-scaled copy of itself. Also space-filling turtle curves are considered, and a turtle curve that is dense in the plane. As a particular result we give an exact relationship between the Koch curve and a turtle curve for the Thue–Morse sequence, where until now for such a result only approximations were known.