subungual melanoma
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2022 ◽  
Vol 48 (1) ◽  
pp. 32-33
Adam I. Rubin ◽  
Bertrand Richert ◽  
Eckart Haneke

2021 ◽  
Vol Publish Ahead of Print ◽  
Byung Jun Kim ◽  
Jinhyun Kim ◽  
Julong Hu ◽  
Yoonjin Kwak ◽  
Sung Tack Kwon

2021 ◽  
pp. 1-4
Aikaterini Tsiogka ◽  
Martin Laimer ◽  
Dimitrios Rigopoulos ◽  
Verena Ahlgrimm-Siess

<b><i>Introduction:</i></b> Nail matrix nevi (NMN) in pediatric patients manifest as longitudinal melanonychia (LM) and can share clinical, dermoscopic, and histopathological characteristics with subungual melanoma. Equivocal findings in childhood LM may reflect dynamic processes during the natural life cycle of NMN in children. <b><i>Case Presentation:</i></b> We present a case of a heavily pigmented LM with equivocal clinical and dermoscopic findings in a 3-year-old Caucasian girl, which exhibited signs of evolution, maturation, and almost complete involution within a short time period during digital follow-up, attributed to the natural course of NMN. <b><i>Discussion/Conclusion:</i></b> Considering the rarity of subungual melanoma in childhood, our case underlines the significance of clinical and digital dermoscopy follow-up in the evaluation of childhood LM in order to avoid unnecessary biopsies and potential permanent nail dystrophy.

Se Jin Oh ◽  
Jongeun Lee ◽  
Jae Ho Lee ◽  
Jaihee Bae ◽  
Ji‐Hye Park ◽  

Yuko Kuriyama ◽  
Akira Shimizu ◽  
Atsushi Tamura ◽  
Sei‐ichiro Motegi

2021 ◽  
Vol 9 (3) ◽  
pp. 57
Christopher J. LaRocca ◽  
Lily Lai ◽  
Rebecca A. Nelson ◽  
Badri Modi ◽  
Brooke Crawford

Despite the changing paradigms of melanoma treatment in recent years, there remains a relative paucity of data regarding subungual melanoma in the literature. From 2002–2018, 25 patients with subungual melanoma were surgically treated at our facility. A retrospective chart review was conducted to collect relevant demographic, clinical, pathologic, and outcomes data. The median age at diagnosis was 69 years. Most patients (60%) were male, and the melanoma lesion was most often located on the foot (68%). Acral-lentiginous was the most common histologic subtype (59%), and the median Breslow thickness was 3.4 mm. Fifteen patients (63%) underwent a sentinel lymph node biopsy as part of their surgical resection, and four of these patients (27%) had metastatic disease in the lymph nodes. In total, 10 patients underwent lymph node dissection of the involved basin. The median follow up was 21 months in this patient population. Age, gender, tumor location, ulceration, and lesion histology were not significantly associated with recurrence free survival (RFS). Increasing Breslow thickness was found to be significantly associated with shorter RFS (HR: 1.07, CI: 1.03–1.55). In total, 13 patients developed a disease recurrence, and RFS rates were 66% at 1 year and 40% at 3 years. Additionally, 91 and 37% of patients were alive at one year and three years, respectively. Subungual melanomas are rare lesions that often have a more advanced stage at diagnosis, which contributes to the poor prognosis of these cutaneous malignancies.

Ignasi Marti-Marti ◽  
Ramon Pigem ◽  
Maria Margarita Narvaez ◽  
Llúcia Alós ◽  
Susana Puig

Yu. I. Pavlov ◽  
V. V. Volkov ◽  
I. A. Gromov ◽  
A. A. Kholopov

Subungual melanoma is a rare malignant tumor, little known to practitioners. Its location makes diagnosis difficult and requires differentiation with conditions such as onychomycosis, panaritium, hematoma, etc. Unsymptomatic onset brings more problems, the error level during visual examination even among experienced oncologists reaches 25–40%, and the average life expectancy of patients with fully manifested melanoma is limited to 3–4 years.So we present a clinical case to emphasize the need for oncological alertness during an outpatient examination of the subungual lesions. A 32-year-old woman came to the reception complaining of a non-healing bleeding, relatively painless wound of the left little toe. The condition was associated with trauma, for about a month she treated the wound herself, “cauterizing” it with antiseptics.After outpatient treatment of a granulating wound, the material was sent for histological diagnosis, which showed the presence of pigmentless melanoma in the stage of active growth. The woman was urgently hospitalized in the oncology department, where 5th finger exarticulation and inguinal-iliac lymphadenectomy were performed successfully. After this, the condition remained stable, but 14 months later there was a formation in the area of the postoperative scar. A study of a new surgical material confirmed the recurrence of malignant melanoma with Clark invasion level 2.In our opinion, outpatient surgeons should not delay histological examination for all ulcerative and granulomatous lesions of the feet, which will improve the differential diagnosis.

2021 ◽  
Vol 5 (1) ◽  
pp. 51-55
Llewelyn Yi Chang Tan ◽  
Chee Hian Tan ◽  
Joel Hua Liang Lim

Melanoma is the most aggressive form of skin cancer affecting patients worldwide and has the potential to metastasize to virtually any organ in the body. Early detection is of paramount importance to minimize patient morbidity and mortality. However, there has been increasing evidence highlighting that geographical and ethnic variations in the clinical presentation of melanoma do exist. Unlike the Western population, the major subtype of melanoma affecting the Asian population is in fact, acral lentiginous melanoma (ALM) and not superficial spreading melanoma (SSM).We hereby present a case of left hallux subungual melanoma with scalp metastasis. This case underscores the importance of the examination of acral skin and the nail apparatus for melanoma in Asians.

2021 ◽  
Vol 33 (2) ◽  
pp. 147
Su-Hyuk Yim ◽  
In Sun Kwon ◽  
Dongkyun Hong ◽  
Kyung Eun Jung ◽  
Young Lee ◽  

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