Novel and efficient synthesis of fused spiro piperidone-cyclopropanes from cascade reaction of 1-acylcyclopropanecarboxamides and polarized olefin

We report here that a series of O-bridged ring fused spiro piperidone-cyclopropane derivatives 3 can be constructed in a single step by the one-pot reaction of 1-acylcyclopropanecarboxamides 1 with polarized...

Oxidative radical ring-opening/cyclization of cyclopropane derivatives

The ring-opening/cyclization of cyclopropane derivatives has drawn great attention in the past several decades. In this review, recent efforts in the development of oxidative radical ring-opening/cyclization of cyclopropane derivatives, including methylenecyclopropanes, cyclopropyl olefins and cyclopropanols, are described. We hope this review will be of sufficient interest for the scientific community to further advance the application of oxidative radical strategies in the ring-opening/cyclization of cyclopropane derivatives.

Carbon–carbon bond forming reactions of acetylenic esters and ketones within frustrated phosphane/borane Lewis pair frameworks

The three-component reactions of bulky diarylbutenylphosphanes with dimethyl acetylenedicarboxylate and the strong boron Lewis acid B(C6F5)3 give the ylide-substituted cyclopropane derivatives.