Vapor-phase conversion of aqueous 3-hydroxybutyric acid and crotonic acid to propylene over solid acid catalysts

Vapor phase conversion of 3-hydroxybutyric and crotonic acid to propylene in a continuous-flow reactor over silica–alumina and niobium catalysts demonstrates a new strategy for producing renewable fuels and chemicals from wastewater carbon.

Reaction kinetics and pathway of crotonic acid conversion in sub- and supercritical water for renewable fuels production

Conversion of waste lipid biomass into renewable fuels using sub- and supercritical water provides an alternative green approach in contrast with the current treatment methods. However, the reaction network of...

Catalyst-free Valorization of Poly-3-hydroxybutyrate to Crotonic Acid

A novel catalyst-free pyrolysis process of poly-3-hydroxybutyrate (PHB) to crotonic acid (CA) in inert nonpolar solvents was developed. After a simple consecutive process of reaction (210 oC for 5 h...

In silico analysis of anticancer effects of anabasine derivatives

In the paper a review of using of different derivatives of anabasine is represented. As well results of computer QSAR investigations of N-(anabazinil)-isobutyric acid, N-(anabazinil)- isovaleric acid, N-(anabazinil)-trimethylacetic acid, N-(anabazinil)-crotonic acid, N-(anabazinil)- chloroacetic acid are represented. For in silico analysis PASS, Molinspiration, OSIRIS software has been used. The results obtained show that summarizing all predictions N-(anabazinil)- isobutyric acid and N-(anabazinil)-chloroacetic acid are acceptable structures for creation new more active and effective derivatives as antitumor medicines. However, considering Cl-containing derivative it was concluded, that this molecule should be changed for decreasing parameters of toxicity with remaining the prospective bioactivity. Most given structures are corresponding to Lipinski’s rule and drug-likeness filters and can be considered as basic structures for constructing some new effective anticancer medicines.

Bio-based crotonic acid from polyhydroxybutyrate: synthesis and photocatalyzed hydroacylation

A novel thermolytic distillation process was developed to depolymerize polyhydroxybutyrate (PHB) for the selective production of crotonic acid. The conditions adopted (170°C, 150 mbar) were applied to pure PHB and...