Adjuvant radiotherapy in primary cardiac sarcoma: case report and literature review

Background: Primary cardiac sarcoma (PCS) is a rare malignancy, and intimal cardiac sarcoma is the rarest. The prognosis is poor with mean survival of 3–12 months even with complete radical resection. There has been no randomised controlled trial or standard guidelines for management of cardiac sarcomas. Treatment is extrapolated from case reports and series. Case presentation: A 59-year-old male diagnosed with primary intimal cardiac sarcoma underwent wide local excision with positive margins. Adjuvant radiotherapy to a total dose of 60 Gray (Gy) was given with good tolerance. Conclusions: Intimal cardiac sarcoma is rare. The risk of local recurrence is high, and efforts must be made to elucidate the role and usefulness of radiotherapy and chemotherapy in these tumours.

A case of undifferentiated pleomorphic cardiac sarcoma

Primary cardiac sarcoma is known to have a poor prognosis due to late presentation, multiple metastases, and complications, challenging treatment options. We present a case of a 78-year-old female patient who was admitted to our hospital with progressive dyspnea and chest pain. Echocardiography revealed multiple masses of different shape and size in the left atrium, the left and right ventricles. Cardiac magnetic resonance confirmed multiple cardiac masses with signs of invasion in the myocardium and heterogeneous late gadolinium enhancement in all these masses. A biopsy of the abdominal mass revealed an undifferentiated pleomorphic sarcoma. We planned chemotherapy and supportive measures. Before the initiation of the chemotherapy, the clinical situation worsened dramatically. Despite the pericardiocentesis, the patient died due to cardiac tamponade. An autopsy revealed a massive tumor in the interatrial septum and multiple metastases in both ventricles, lungs, and abdomen.

Multi-disciplinary Frameworks for the Treatment of Primary Cardiac Sarcoma

Multi-disciplinary teams present the framework in the increasingly challenging care provided for patients. Wang et al. present a 37 year old female who is 35 weeks pregnant when a rare cardiac angiosarcoma is diagnosed.

Complete resolve of primary cardiac sarcoma by chemotherapy: A case report

Primary cardiac tumors (PCT) are rare with high mortality rate and low survival. There are several treatment approaches in the PCT management. Complete surgical resection is the main base of treatment and there is disagreement on adjuvant chemotherapy or radiotherapy after surgical resection. In this case report, complete remission of the relapsed non-metastatic cardiac synovial sarcoma was observed after salvage chemotherapy and complete surgical resection.